Medication-induced drug disorders have been evident for nearly a century and labeled with a variety of names. French dermatologist Dr. Vincent Descamps, who has been at the forefront of DRESS syndrome since the mid-1990s, joins us to review this historically misunderstood and under-reported illness. We'll also discuss the history of how an international team of researchers and physicians identified the clinical condition known as DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms).

Interview: Dr. Vincent Descamps (Professor of Dermatology at the Bichat Claude Bernard Hospital, University Denis Diderot in Paris, France) June, 2019 in Quebec, Canada.

PUBLICATIONS/RESOURCES:

DRESS syndrome: https://docs.wixstatic.com/ugd/cac731_643993b7381f4c85b7d4b62dce42087b.pdf
Diagnosis of DRESS (Drug Reaction With Eosinophilia and Systemic Symptoms) in the Intensive Care Unit: Essential But Challenging: https://journals.lww.com/shockjournal/Fulltext/2013/11000/Diagnosis_of_DRESS__Drug_Reaction_With.14.aspx
French dermatologists call for antiviral therapy in DRESS: https://hhv-6foundation.org/drug-hypersensitivity/french-dermatologists-call-for-antiviral-therapy-in-dress
Saliva polymerase chain reaction assay for detection and follow-up of herpesvirus reactivation in patients with drug reaction with eosinophilia and systemic symptoms (DRESS): https://pubmed.ncbi.nlm.nih.gov/23426332/
Drug rash with eosinophilia and systemic symptoms (DRESS) in patients receiving strontium ranelatez: https://pubmed.ncbi.nlm.nih.gov/23361875/
Human herpesvirus 6 involvement in paediatric drug hypersensitivity syndrome: https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.13592
The DRESS Syndrome: A Literature Review: https://www.amjmed.com/article/S0002-9343(11)00258-0/fulltext
Chapter 11 - HHV-6A and HHV-6B in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms: https://www.sciencedirect.com/science/article/pii/B9780444627032000112
Service de Dermatologie/Hôpital Bichat - Claude-Bernard: https://www.aphp.fr/service/service-16-011
Chronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report: https://onlinelibrary.wiley.com/doi/10.1002/ccr3.3680#.X90Agxjv1sI.twitter