Hypertension affects one third of humans. Untreated hypertension, shortens life expectancy by five years because it's a major cause of heart failure, renal failure, strokes, and coronary disease. The mortality due to hypertension has increased  more than 30% in the last three decades. And the sad fact is that hypertension is uncontrolled in the majority of hypertensive patients, but it seems there's a breakthrough treatment.

Angiotensinogen is a protein, it's mainly produced by the liver. If we stop the production of Angiotensinogen in the liver, then the whole. Renin angiotensin system will be silenced. And we have the results of the study on DNA silencing available.