In this episode I talk with Dr. Mark Pimentel, a leader in the small intestinal bacterial overgrowth (SIBO) and irritable bowel syndrome (IBS) world.

We talk about what his team is doing to push research forward for SIBO and IBS, new developments in SIBO, breath testing and gasses produced, as well as things that will be coming out soon for treatment.

In this episode, we cover:

What is SIBO [4:29]

What the team is working on [5:46]

Keeping an open mind as a scientist [9:02]

The controversy of breath testing [10:01]

Hydrogen sulfide [13:24]

This episode is sponsored by FODZYME, the world's first enzyme blend that targets FODMAPs, gas-causing carbohydrates and common gut triggers.

Mixing FODZYME with your food allows the enzymes to integrate and break down the FODMAPs lactose, GOS, and fructan, before they can affect your gut. Through a unique formula and powder form for maximum efficacy, FODZYME can help you reduce overall FODMAP load, support better digestion and enable nutritional diversity for optimal health.

Say goodbye to digestion drama with the help of FODZYME. Learn more at fodzyme.com and use code GUTSHOW at checkout to save 20% off any single order

Mentioned in this episode:

REIMAGINE Study: https://csmast.com/current-research/

Breath testing for SIBO and IMO: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10496284/

Research articles from the MAST team: https://csmast.com/scientific-articles/

Indian consensus statements on IBS: https://pubmed.ncbi.nlm.nih.gov/36961659/

Join the MASTER Method Membership: https://www.ibsmastermethod.com/master-method

About our guest:

Mark Pimentel, MD, is a Professor of Medicine at Cedars-Sinai. Dr. Pimentel is also the Executive Director of the Medically Associated Science and Technology (MAST) program at Cedars-Sinai, an enterprise of physicians and researchers dedicated to the study of the gut microbiome in order to develop effective diagnostic tools and therapies to improve patient care. Dr. Pimentel is also a Professor of Medicine at the Geffen School of Medicine, University of California, Los Angeles (UCLA.)

As a physician and researcher, Dr. Pimentel has served as a principal investigator or co-investigator for numerous basic science, translational and clinical investigations of irritable bowel syndrome (IBS) and the relationship between gut flora composition and human disease. This research led to the first ever blood tests for IBS, ibs-smartTM, the only licensed and patented serologic diagnostic for irritable bowel syndrome. The test measures the levels of two validated IBS biomarkers, anti-CdtB and anti-vinculin.

A pioneering expert in IBS, Dr. Pimentel’s work has been published in the New England Journal of Medicine, Annals of Internal Medicine, American Journal of Physiology, American Journal of Medicine, American Journal of Gastroenterology and Digestive Diseases and Sciences, among others. Dr. Pimentel has presented at national and international medical conferences and advisory boards. He is a diplomate of the American Board of Internal Medicine (Gastroenterology,) a fellow of the Royal College of Physicians and Surgeons of Canada and a member of the American Gastroenterological Association, the American College of Gastroenterology, and the American Neurogastroenterology and Motility Society.

Learn more about Dr. Pimentel’s work:

https://www.cedars-sinai.org/research/areas/science-tech.html

Twitter: https://twitter.com/MASTprogram

Instagram: @mastprogram

Connect with Erin & the Gutivate team:

IG: @erinjudge.rd or @gutivate

Website: www.gutivate.com

Schedule a consult: bit.ly/gutivateconsult

FREE: IBS Fundamentals Mini Course:

https://www.ibsmastermethod.com/ibs-fundamentals-sign-up

Join The GUT Community:

The Facebook group for those with IBS and digestive health conditions to connect, encourage one another, and dive deeper into the topics we cover on The Gut Show. Join here: https://www.facebook.com/groups/thegutcommunity

Track your symptoms & understand your body better:

My Gut Journal is a 90 day gut tracker to build awareness in your mind & body. Get yours at https://gutivate.com/store/mygutjournal