Interview about the UK Biobank with Dr. Christopher Whelan

Proteomics in Proximity

Jul 27 2023 • 36 mins

Welcome to Olink Proteomics in Proximity Podcast!

Below are some useful resources from this episode:

Highlighted article from the UK Biobank Pharma Proteomics Project (UKB-PPP): Styrkarsdottir U, Lund SH, Thorleifsson G, Saevarsdottir S, Gudbjartsson DF, Thorsteinsdottir U, Stefansson K. Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource. Arthritis Rheumatol. 2023 Apr;75(4):544-552. doi: 10.1002/art.42376. Epub 2022 Dec 28. PMID: 36239377. https://pubmed.ncbi.nlm.nih.gov/36239377/

Highlighted platform that was used to measure proteins in this study with a next-generation sequencing (NGS) readout (Olink® Explore 3072): https://olink.com/products-services/explore/

UKB-PPP consortium, one of the world’s largest scientific studies of blood protein biomarkers conducted to date: https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-largest-scientific-studies

ENIGMA consortium, an international effort to understand brain structure and function based on imaging and genetic data: https://enigma.ini.usc.edu/about-2/

SCALLOP consortium, a collaborative framework for discovery and follow-up of genetic associations with proteins on the Olink Proteomics platform: https://olink.com/our-community/scallop/

ClinVar, a public archive of supporting evidence of human variations and phenotypes from the National Center for Biotechnology Information (NCBI): https://www.ncbi.nlm.nih.gov/clinvar/intro/

GWAS (genome-wide association studies): https://www.genome.gov/genetics-glossary/Genome-Wide-Association-Studies

Learn more about some of the scientists mentioned in the podcast who are performing cutting-edge research:

Dr. Kári Stefánsson, Founder and CEO of deCODE genetics: https://www.decode.com/management/

Dr. Claudia Langenberg, Director of Queen Mary’s Precision Health University Research Institute (PHURI): https://www.bihealth.org/en/research/research-group/computational-medicine

Dr. Jochen Schwenk, Professor of Translational Proteomics at SciLife Lab: https://www.scilifelab.se/researchers/jochen-schwenk/

Dr. Karsten Suhre, Professor of Physiology and Biophysics at Weill Cornell Medicine-Qatar: https://physiology.med.cornell.edu/people/karsten-suhre-ph-d/

Dr. Paul Thompson: Director at ENIGMA Center for Worldwide Medicine, Imaging, & Genomics; Professor in the Keck School of Medicine at USC: https://keck.usc.edu/faculty-search/paul-m-thompson/

Would you like to subscribe to the podcast on your favorite player or app? You can do so here:

Apple Podcasts: https://apple.co/3T0YbSm

Spotify Podcasts: https://open.spotify.com/show/2sZ2wxO...

Google Podcasts: https://podcasts.google.com/feed/aHR0...

Amazon Music: https://music.amazon.com/podcasts/d97...

Podcast Addict:

You Might Like

Hidden Brain
Hidden Brain
Hidden Brain, Shankar Vedantam
Radiolab
Radiolab
WNYC Studios
Science Friday
Science Friday
Science Friday and WNYC Studios
StarTalk Radio
StarTalk Radio
Neil deGrasse Tyson
Sasquatch Chronicles
Sasquatch Chronicles
Sasquatch Chronicles - Bigfoot Encounters
Something You Should Know
Something You Should Know
Mike Carruthers | OmniCast Media | Cumulus Podcast Network
This Podcast Will Kill You
This Podcast Will Kill You
Exactly Right Media – the original true crime comedy network
Tooth & Claw: True Stories of Animal Attacks
Tooth & Claw: True Stories of Animal Attacks
Wes Larson, Jeff Larson, Mike Smith | QCODE
Paranormal Mysteries Podcast
Paranormal Mysteries Podcast
Paranormal Mysteries | Unexplained Supernatural Stories
Science Vs
Science Vs
Spotify Studios
The Confessionals
The Confessionals
Merkel Media
Blurry Creatures
Blurry Creatures
Blurry Creatures
Real Ghost Stories Online
Real Ghost Stories Online
Real Ghost Stories Online | Paranormal, Supernatural & Horror Radio