In the second episode of The Rising Tide Podcast, Dr. Ali Khaki of Stanford University sits down with the Center for Genomic Interpretation again to discuss the promises and pitfalls of precision medicine, potential consequences when FDA approvals extend beyond populations of patients and clinical trials, how to improve selection of patients for therapy, and concepts that all stakeholders should consider for these complex topics. This particular episode is geared toward anyone seeking detailed, in-depth perspectives about oncology precision therapies.