Join us in this insightful conversation as Ajay and Loong sit down with Dr. Hon Weng Chong an expert in the field of brain-on-chip technologies and co-founder of  Cortical Labs. They delve into the potential of these technologies in revolutionizing drug discovery and biotechnology. From the challenges of modeling neurodegenerative diseases to the exciting prospects of faster and personalized clinical trials, this discussion provides a deep dive into the future of the CNS field.

Timestamps and Topics:

[00:00:00] Introduction

[00:02:15] Overview of Brain-on-Chip Technologies

• Understanding the fundamentals of brain-on-chip technology.

[00:10:45] Challenges in Neurodegenerative Disease Modeling

• The complexities and time-consuming nature of modeling diseases like Alzheimer's.

[00:25:30] Correlation Between Chips and Human Responses

• Exploring the potential correlation between chip-based models and human responses.

[00:38:12] Accelerating Drug Discovery

• Discussing how brain-on-chip technologies can significantly speed up drug discovery processes.

[00:49:05] Progeria Case Study

• Insights into a progeria case study and challenges faced in translating results from mice to humans.

[01:01:30] Challenges in CNS Field

• Addressing the slow pace of advancements in the Central Nervous System (CNS) field.

[01:03:00] Future Prospects and Closing Thoughts

• Highlighting the potential of brain-on-chip technologies and their impact on addressing major challenges in biotechnology.

Check out Hon’s Stuff:

- Cortical Labs: https://corticallabs.com/

Check out Ajay's Stuff:

- EntryLevel: https://entrylevel.net

- Website: https://ajayprakash.net

Check out Loong's Stuff:

- QDX: https://qdx.co

- Automera: https://automeratx.com

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