Episode 172: Sarcomas Unveiled: Advances in Rare Cancer Care
In this episode, Jonathan is joined by Brian Van Tine, Professor of Medicine in medical oncology and Professor of Paediatrics at the Washington University School of Medicine (WUSM) in St. Louis, Missouri, USA, to provide an overview of his clinical interest in soft tissue and bone sarcomas. The pair explore immunotherapy, specifically monoclonal antibodies and immune checkpoint blockade, and further dive into metabolomics and its relevance to oncology.
Use the following timestamps to navigate the content in this episode:
(00:00)-Introduction
(03:50)-Brian’s inspiration for pursuing oncology
(04:43)-The rare tumour world and sarcomas
(06:13)-Immunotherapy trials
(09:21)-Treatment options for advanced alveolar soft part sarcoma
(13:52)-Genetic mutations in malignant diseases
(17:13)-Argininosuccinate synthetase 1
(22:49)-Metabolomics
(25:55)-Anthracycline-associated cardiotoxicity in patients with soft tissue sarcoma
(28:40)-Treatments available for soft tissue tumours
(31:49)-Three wishes
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