Gene Therapy for Hemophilia: Dream or Reality?

Canadian Hemophilia Society

Gene therapy has remained a constant prospect in the sphere of hemophilia treatment. For over two decades and the question remained: Is this just a dream, or could it one day become a reality?

Hemophilia gene therapy has finally been approved.

David Page talks to hemophilia specialists that will dive deep into understanding how the treatment works, its significance in advancing treatment, and how a one time treatment could change a severe condition to a milder one.Though not a definitive cure, gene therapy for hemophilia has transformed the dream of a cure into a reality for the future.

David and his guests will provide exclusive insights into one of the most significant medical breakthroughs of our era.

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Health & FitnessHealth & Fitness

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Introducing: Gene Therapy for Hemophilia: Dream or Reality?

Introducing: Gene Therapy for Hemophilia: Dream or Reality?

This is a series of podcasts featuring well-known patient and physician experts will provide important answers, for example: What are the clinical trial results in hemophilia GT? What is the shared decision-making process in hemophilia GT? What is it like to receive it? What other approaches to hemophilia GTs are down the road?David Page is your host and explores the possibilities with medical experts. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episodes

DEBATE: If gene therapy for hemophilia A were available in Canada tomorrow, Would you want to receive it?

DEBATE: If gene therapy for hemophilia A were available in Canada tomorrow, Would you want to receive it?

In this podcast, Cleaven Pagani, Rick Waines, Paul Wilton and Emil Wijnker, all with severe hemophilia A and also members of the Canadian Hemophilia Society Blood Safety and Supply Committee, are asked to debate the question: “If gene therapy for hemophilia A were available in Canada tomorrow, would you want to receive it?”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What Other Approaches To Hemophilia Gene Therapies Are Down The Road?

What Other Approaches To Hemophilia Gene Therapies Are Down The Road?

The first generation of gene therapy for hemophilia, called gene insertion or gene addition, is now a reality, but it is not for everyone. Dr. Glenn Pierce explores other approaches to gene therapy in the research pipeline that in the future may be more efficacious for a longer time for more people. Glenn is a long-time researcher in coagulation products for hemophilia and is currently the Medical Vice President of the World Federation of Hemophilia.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How Might Gene Therapy Be Delivered In Canada?

How Might Gene Therapy Be Delivered In Canada?

In this podcast, Dr. Jerry Teitel explores how gene therapy for hemophilia A and hemophilia B might be delivered to patients across Canada in an equitable way, even though the administration will occur in only some sites. He describes the follow-up that is required in the critical months following administration to get the best results possible. Dr. Teitel is a Professor of Medicine at the University of Toronto, and Medical Director of the Hemophilia Treatment Program at St. Michael’s Hospital in Toronto, Ontario.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

How Might Gene Therapy Be Funded In Canada?

How Might Gene Therapy Be Funded In Canada?

Gene therapy—a high-cost, one-time, potentially life-changing treatment—presents unique challenges for governments that make decisions on funding innovative treatments. Dr. Durhane Wong-Rieger presents creative ideas on new ways to think about how gene therapy for hemophilia A and B could be funded in Canada. Durhane is a health coach, frequent lecturer and author. She is the President and CEO of the Canadian Organization for Rare Diseases and chair of Rare Diseases International.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What Is The Shared Decision-Making Process In Hemophilia Gene Therapy?

What Is The Shared Decision-Making Process In Hemophilia Gene Therapy?

In this podcast, Dr. Jerry Teitel describes the process of shared decision-making prior to gene therapy in hemophilia A and hemophilia B, and how the nature of gene therapy itself makes shared decision-making so important. Dr. Teitel is a Professor of Medicine at the University of Toronto, and Medical Director of the Hemophilia Treatment Program at St. Michael’s Hospital in Toronto, Ontario.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What Don’t We Know About Gene Therapy For Hemophilia?

What Don’t We Know About Gene Therapy For Hemophilia?

In this podcast, Dr. Glenn Pierce explores what we know we don’t know and what we don’t even know we don’t know about the brand-new treatment which is gene therapy for hemophilia A and B. Glenn is a long-time researcher in coagulation products for hemophilia and is currently the Medical Vice President of the World Federation of Hemophilia.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What Is It Like To Receive Gene Therapy?

What Is It Like To Receive Gene Therapy?

In this podcast, Brian O’Mahony explores the patient experience of gene therapy for hemophilia, from the shared decision-making process prior to gene therapy, to the administration itself, to the intense follow-up in the first months and finally, the long-term follow-up. Brian is Chief Executive Officer of the Irish Haemophilia Society and a former president of the World Federation of Hemophilia and the European Haemophilia Consortium.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What Are The Clinical Trial Results In Hemophilia Gene Therapy?

What Are The Clinical Trial Results In Hemophilia Gene Therapy?

In this podcast, Dr. David Lillicrap presents the results of clinical trials in hemophilia A and hemophilia B gene therapy. He describes how high factor VIII and IX levels can rise, how predictable this response is from person to person, and how long the therapy may be effective. Dr. Lillicrap is a Professor in the Department of Pathology and Molecular Medicine at Queen’s University in Kingston, Ontario, and is world renowned for his research in hemophilia gene therapy.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Who Is Eligible For Hemophilia Gene Therapy?

Who Is Eligible For Hemophilia Gene Therapy?

In this podcast, Brian O’Mahony explores why gene therapy for hemophilia A and Hemophilia B is not for all patients. He describes what makes a person eligible, and in some cases ineligible, to receive the treatment. Brian is Chief Executive Officer of the Irish Haemophilia Society and a former president of the World Federation of Hemophilia and the European Haemophilia Consortium.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What Is Gene Therapy For Hemophilia?

What Is Gene Therapy For Hemophilia?

In this podcast, Dr. David Lillicrap describes in easy-to-understand language what gene therapy for hemophilia A and hemophilia B is, how it is administered and how it works. Dr. Lillicrap is a Professor in the Department of Pathology and Molecular Medicine at Queen’s University in Kingston, Ontario, and is world renowned for his research in hemophilia gene therapy.Canadian Hemophilia SocietySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Introducing: Gene Therapy for Hemophilia: Dream or Reality?

Introducing: Gene Therapy for Hemophilia: Dream or Reality?

This is a series of podcasts featuring well-known patient and physician experts will provide important answers, for example: What are the clinical trial results in hemophilia GT? What is the shared decision-making process in hemophilia GT? What is it like to receive it? What other approaches to hemophilia GTs are down the road?David Page is your host and explores the possibilities with medical experts. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.