vlmd rounds

Vyvyane Loh, MD

This podcast focuses on bringing Art and Science back to Medicine.
We've lost the art of healing and our practices lag the impressive developments in the biological sciences. My goal is to reignite interest in science and to restore a regard for humanity in the face of ever-growing disengagement in my profession.
Subscribe if:
-you are a geek or a nerd (the difference is in social skills--I identify as Geek--but we're all inclusive here, Kumbaya!)
-your AQ (Attention Quotient) exceeds that of a goldfish (yes, the episodes are long)
-you think: the-hip-bone-is-connected-to-the-knee-bone...but why?
-you secretly harbour the suspicion that you're smarter than your doctor
-you are a med student/professional who wants to know what your expensive education (which you are still paying for) did NOT give you
-you love green tea, dance and animals, none of which is featured here extensively, but you're my kind of person
Subscribe to my newsletter at vyvyanelohmd.com

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Health & FitnessHealth & Fitness

Episodes

Reviewing Dayspring and Attia
Feb 10 2024
Reviewing Dayspring and Attia
Send us a Text Message.Fuzzy science” abounds in the world, and even luminaries fall into its trap sometimes. This review clarifies the mis-explanations of important concepts in lipid science that were discussed in Peter Attia’s podcast. The interview with Dr. Thomas Dayspring resulted in a 7 hour series that promised a deep dive into cholesterol and lipoproteins. Lipid science is a complex and ever-evolving field. Understanding some of the basic tenets of the field helps us traverse more complicated topics. The intention of this review is to help clarify the important points Dr. Dayspring made and to open up the scope of the discussion by examining less considered aspects of cholesterol, lipoproteins and their functions. The deep dive into the topic by Drs. Attia and Dayspring was indeed much needed and appreciated and this review acts merely as supplementary commentary or footnotes to the discussion. Since Attia and Dayspring devoted an impressive 7 hours to their discussion, the 2 hour length in this episode respects the time and effort that went into their series by attending to their points in detail. Let me know your thoughts in the comments. What questions do you have from Dr. Dayspring’s interview?Time stamps: 00:00 Intro 05:11 Criteria for review 06:53 Aligning with their intention 09:29 Feynman's scientific principles 11:28 Phospholipids 18:46 Lipid Rafts 30:54 TD: "All cells make cholesterol." 45:28 The Rare Exceptions 50:45 Lipoproteins & cholesterol in artery walls 1:05:59 Pools of Cholesterol 1:09:50 Lipoprotein density1:12:23 How apoproteins are bound 1:15:04 Statins & liver selectivity 1:21:05 Cholesterol functions & metabolism 1:31:02 HDL 1:34:11 RBC membrane cholesterol 1:36:59 Lipoprotein lineages 1:40:48 ApoE 1:50:40 Cholesterol's function in lipoproteins 1:59:55 Unregulated apoB 2:02:23 Conclusion  My practice: https://vyvyanelohmd.com/work-with-me/