Mayo Clinic Center for Sleep Medicine

What is transvenous phrenic nerve stimulation?  When should we use it for patients with central sleep apnea?  Dr. Timothy Morgenthaler, a sleep specialist at Mayo Clinic, answers these questions.

Do all patients with CPAP related treatment emergent central sleep apnea need a change in management?  Dr. Timothy Morgenthaler, a sleep specialist at Mayo Clinic, answers this question.

Is CSA harmful in patients with heart failure? When should it be treated?  What is the role of augmented servo-ventilation? Dr. Sean Caples, a sleep specialist at Mayo Clinic, answers these questions.

Idiopathic hypersomnia is probably at least as common and possibly more common than narcolepsy.  In this podcast, Dr. Michael Silber discusses current approaches to its diagnosis and pharmacologic management.

Many date the start of the field of Sleep Medicine to the discovery of REM sleep by Eugene Aserinsky and Nathaniel Kleitman in 1953.  But was it actually discovered 27 years earlier by Russian investigators?  In this podcast Dr. Michael Silber discusses the fascinating story of how REM sleep was identified and what this means for Sleep Medicine.

The number of medications available to treat narcolepsy has grown dramatically in the last few years. While these have changed the landscape for patients, the future may hold even better treatments. In this podcast, Dr. Michael Silber discusses the currently available new medications and the development of orexin receptor agonists which may transform narcolepsy management.

How should we diagnose narcolepsy? In this podcast, Dr. Michael Silber explains when measuring CSF Orexin-A can be helpful and how to interpret the results.

The multiple sleep latency test was developed in 1978. While it is still the standard test used for the diagnosis of central disorders of hypersomnolence, its interpretation is complex and many factors can affect the validity of its results. In this podcast, Dr. Michael Silber discusses the practical use of the MSLT in 2024.

Cognitive behavioral therapy is the first-line therapy recommended for chronic insomnia. What does it comprise and who should teach it? Is Internet-based therapy available and effective? In this podcast, Dr. Mark Hansen discusses practical use of CBT-I for healthcare practitioners.

The search for the perfect hypnotic continues. In this podcast, Dr. Bhanu Kolla discusses the new dual orexin receptor antagonists, antidepressants and other agents used to treat insomnia.

The Z drugs are the most commonly prescribed hypnotics but are widely misunderstood. In this podcast, Dr. Bhanu Kolla discusses truth and myths for the clinician prescribing these drugs.

All of us who treat restless legs realize that current therapies are far from perfect. In this podcast, Dr. Michael Silber discusses possible future approaches, some already starting to be available.

Many physicians are reluctant to prescribe even low-dose opioids for chronic problems such as refractory restless legs. But opioid therapy can be life transforming for the correct patient. In this podcast, Dr. Michael Silber discusses the appropriate use of opioids for patients with restless legs refractory to other medications.

Patients are still presenting to sleep specialists on high doses of dopamine agonists with intense augmentation and profound insomnia. In this podcast, Dr. Michael Silber discusses how to manage patients with this distressing problem.

How do we define low iron stores in restless legs? In this podcast, Dr. Michael Silber discusses diagnosis of iron deficiency and how oral and intravenous iron should be administered in restless legs syndrome.

The last few years have shown a major change in first-line management of restless legs. In this podcast, Dr. Michael Silber discusses why gabapentinoids are now first-line therapy rather than dopamine agonists, how they are used, and whether there is any role still for the dopaminergic drugs.