I am delighted to reconnect with Dr. Felice Gersh today for our fourth discussion.  Dr. Gersh is a globally recognized expert on women's hormones. As the Medical Director of the Integrative Medical Group of Irvine, she often collaborates with numerous research organizations.  In our discussion today, we dive into cardiovascular disease risks and menopause, highlighting the metabolic transition that menopause represents and exploring risk factors like preeclampsia, gestational diabetes, and PCOS. We get into the use of oral contraceptives, particularly before the age of 20, early puberty, and premature ovarian failure, while examining the role of the RAS system, synthetic hormones, and the differences between estrone and estradiol. We discuss the optimal timing for starting hormone replacement therapy and explain why we should love our menstrual cycles, addressing the risks related to circadian rhythm disruption. We also look at arterial changes, cholesterol dynamics, the autonomic nervous system, gut health and cardiac wellness in menopause, and proactive ways to support our bodies.  I am confident you will find today’s conversation with Dr. Felice Gersh most enlightening and informative. IN THIS EPISODE YOU WILL LEARN: Why women need to understand basic female physiology  How pregnancy-induced insulin resistance and leaky gut can lead to cardiovascular issues later in life Dr. Gersh highlights the importance of metabolic health in pregnancy and menopause Why it is risky for young women to use oral contraceptives What irregular bleeding in perimenopausal women might indicate Why the inflammatory response is critical for survival, even though it may become problematic if not properly regulated How estrogen is a family of hormones, not a single hormone How estradiol differs from estrone Why should menopause be treated like any other hormone deficiency state? The optimal time for hormone replacement therapy Why post-menopausal women are more susceptible to heart attacks than men  Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Felice Gersh On her website: Integrative Medical Group of Irvine Instagram All of Dr. Gersh’s books are available on Amazon Ep. 297 Dr. Felice Gersh: Estrogen, Immunity & Menopause Mysteries Ep. 237 Perimenopause and Menopause: What You Didn’t Know with Dr. Felice Gersh Ep. 221 Part 1- An Integrative Approach to PCOS and Menstrual Irregularities with Dr. Felice Gersh

I am thrilled to have the award-winning personal trainer, Doug Bopst, joining me today.  Doug is also an author and host of the Adversity Advantage Podcast. He is a former convicted felon and drug addict who spent time in jail and is now on a mission to inspire others to conquer adversity and realize their fullest potential. Today, Doug and I engage in a thought-provoking conversation on gratitude, how exercise enables individuals to confront their fears and connect with themselves, the distinction between healthy and unhealthy habits, and the restrictions associated with seeking validation externally. We also discuss the transformative power of resilience, faith, and learning to be comfortable with being uncomfortable.  Doug’s remarkable journey from adversity to triumph serves as a beacon of inspiration for countless individuals seeking transformation, and I am confident that our conversation will resonate deeply with listeners. Stay tuned for Doug’s profound insights on personal development. IN THIS EPISODE YOU WILL LEARN: How gratitude reshaped Doug’s life How people use drugs as a coping mechanism to numb emotional pain Doug explains how he realized he had power and was able to control his life despite feeling powerless  How exercise can catalyze self-discovery and growth Why anxiety and stress are normal responses for those raised in troubled environments Why do some individuals constantly seek external validation instead of seeking self-worth internally? How self-awareness can help to conquer the need for external validation The benefits of coaching and therapy for overcoming unhealthy relationships with food Why many women avoid pushing themselves to the limit during workouts How faith helped Doug to transform his pain and become a better person Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Doug Bopst On his website Instagram The Adversity Advantage Podcast

I am delighted to have the remarkable Dr. William Li joining me again today. He was previously with me on Episode 260, which became one of the most popular podcasts in 2023.  Dr. Li is a world-renowned physician-scientist and New York Times bestselling author known for his role as President and Medical Director of the Angiogenesis Foundation.  In our conversation today, we dive into the vocabulary surrounding health and microbiome-supporting foods, exploring how to measure the microbiome, the benefits of fermented foods, and the role of the appendix. We also look at pre, and post-biotics, strategies for supporting the microbiome after a colonoscopy prep, foods to avoid, immune function, and metabolic nuances, and discuss the differences between subcutaneous visceral fat, brown fat, and white fat, and polyphenol-rich beverages.  I know you will find today’s conversation with Dr. William Li as enlightening as I did. I eagerly anticipate inviting him back to the podcast later this year. IN THIS EPISODE YOU WILL LEARN: Dr. Li explains the importance of the gut microbiome  The interrelationship between the microbiome, body fat, and the metabolism How to measure your gut microbiome Foods that promote gut health and support the microbiome The role of the appendix How a colonoscopy prep impacts the gut microbiome How excess body fat can fuel the metabolism rather than slowing it down Why sleep is crucial for metabolism The role of brown fat in weight loss The benefits of polyphenols in coffee and tea Bio: William W. Li, MD, is an internationally renowned physician, scientist, and New York Times bestselling author of “Eat to Beat Your Diet: Burn Fat, Heal Your Metabolism, Live Longer”. His groundbreaking work has led to the development of more than 30 new medical treatments and impacts care for more than 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. His TED Talk, “Can We Eat to Starve Cancer?” has garnered more than 11 million views. Dr. Li has appeared on Good Morning America, CNN, CNBC, LIVE with Kelly and Ryan, and the Rachael Ray Show, and he has been featured in USA Today, Time Magazine, The Atlantic, and O Magazine. He is the president and medical director of the Angiogenesis Foundation. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. William Li On Social media: @ Dr William Li On his website Sign up for Dr. Li’s free newsletter Ep. 260 Eat To Beat Your Diet: Achieve a Balanced and Healthy Lifestyle with Dr. William Li

Today, I am thrilled to bring you our seventh AMA episode. I am super excited to connect with all of you today to share valuable insights and answer your questions about dysfunctional uterine bleeding, hormone replacement therapy, perimenopause, and menopause. I will also be addressing queries on blood loss thresholds and dysfunctional uterine bleeding and offering strategies for managing endometriosis and cravings.  Join me as I answer many questions from listeners, shedding light on all these critical concerns and several more. I love doing the AMA episodes, and I know you love listening to them, so keep your questions coming! IN THIS EPISODE YOU WILL LEARN: How an estrogen and progesterone imbalance could cause persistent bleeding  How much blood loss should there be in a menstrual cycle? Why some women crave sweet and salty foods at night during perimenopause and menopause Strategies for managing cravings during perimenopause and menopause How endometriosis often links to autoimmunity and digestive issues Why would someone experience unusual symptoms like itchy ears, crankiness, and bloating in menopause? Various hormone replacement therapy options for perimenopause Why you should implement lifestyle changes before considering HRT The benefits of oral progesterone for sleep and bone health Join my free Facebook group to have me answer your questions personally, or you can send your questions to my admin team (support@cynthiathurlow.com) Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com

Dr. Thomas Dayspring joins me again today for the third class in our Lipid Masterclass Series. Dr. Dayspring brings a wealth of expertise as a certified specialist in internal medicine and clinical lipidology, holding fellowships with the American College of Physicians and the National Lipid Association. This hour-long class is devoted to women's health and abnormal lipids. We continue with our conversation about ApoB, discussing ways to look at other lipid abnormalities related to abnormal ApoBs and talking about our ideal lab values and lifestyle modifications, briefly touching on my lipid journey and the medication I have been taking for the past six months. We examine diagnostics and their limitations, getting into CACs, coronary artery calcification scoring, CIMT, the labs we need to look at, the role of Lp(a), and how it affects our heart. We look into the changes women experience from losing estrogen in menopause, clues women can use to predict future cardiovascular risk, how estrogen helps clear LDL from the body, and the changes occurring with menopause, including higher ApoBs. We also dive into risks women face for cardiovascular disease, the impact of the Women's Health Initiative study, and absorption and synthesis challenges with cholesterol. Stay tuned for more! IN THIS EPISODE YOU WILL LEARN: Why ApoB testing for inherited lipoprotein disorders is essential  Why hypo beta lipoproteins (HDL) are critical for maintaining good health The benefits of a holistic approach to treating high cholesterol The three stages of prevention for atherosclerosis How Lp(a) impacts heart health The importance of assessing early heart function through Lp(a) testing How your pregnancy history can help in predicting your risk for cardiovascular disease Why should women be more concerned about cardiovascular disease than breast cancer? How the Women’s Health Initiative led gynecologists to be more cautious about prescribing HRT How genetically mediated cholesterol abnormalities can impact our ability to absorb and synthesize cholesterol   Bio: Thomas Dayspring MD is a Fellow of both the American College of Physicians and the National Lipid Association and is certified in internal medicine and clinical lipidology. After practicing in New Jersey for 37 years, in 2012, he moved to Virginia to serve as an educational director for a nonprofit cardiovascular foundation until mid-2019 as a Chief Academic Advisor for two major CV laboratories. Since then, he has served as a virtual cardiovascular / lipidology educator. Career-wise he has given over 4000 domestic (in all 50 states) and several international lectures, including over 600 CME programs on atherothrombosis, lipids/lipoproteins (and their treatment), vascular biology, biomarker testing, and women’s cardiovascular issues. He has authored several manuscripts and lipid textbook chapters and performed several podcasts. For several years, he was an Associate Editor of the Journal of Clinical Lipidology. He was the recipient of the 2011 National Lipid Association’s Presidents Award for services to clinical lipidology and the 2023 Foundation of NLA Clinician/Educator Award. He has over 34K followers on his educational Twitter (X) feed (@Drlipid). He has Gold Heart Member status as a professional member of the American Heart Association, and he serves as a Social Media Ambassador for the European Atherosclerosis Society and the National Lipid Association. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On Twitter (@DrLipid) LinkedIn

It is my pleasure today to introduce Jodi Cohen, a best-selling author, award-winning journalist, functional practitioner, and the Founder of Vibrant Blue Oils, where her training in nutritional therapy and aromatherapy come together to craft unique and exclusive proprietary blends of organic and wildcrafted essential oils.  Jodi has assisted more than 50,000 individuals in overcoming brain-related issues such as anxiety, insomnia, and autoimmunity. In our discussion today, we dive into the fundamental aspects of essential oils, looking at what they are and how they work. We examine the role of the blood-brain barrier and the influence of the autonomic nervous system, focusing on the parasympathetic nervous system and vagus nerve. We explore the importance of vagal tone, the implications of vagal nerve dysfunction and toxicities, and the lymphatic system while also looking at the role of fascia in memories and trauma and the profound effects of essential oils on sleep quality, weight management, and more.  I am excited to share this insightful conversation with Jodi Cohen, as it provides invaluable insights into the vast potential of essential oils in promoting holistic well-being. IN THIS EPISODE YOU WILL LEARN: What essential oils are and how they work clinically The most effective way to use essential oils How emotional or mental dangers can trigger the autonomic nervous system   The autonomic nervous system can cause inflammation, impaired digestion, and compromised immune function if it is constantly activated Stimulating the vagus nerve can improve resilience and reduce stress Some natural ways to stimulate the vagus nerve The connection between the brain and digestion and how stress can impact digestion and overall health How fascia intertwines with the lymph and vagus nerve Essential oils can facilitate emotional release The benefits of essential oils for sleep and weight management during perimenopause and menopause Bio: Jodi Sternoff Cohen is a bestselling author, award-winning journalist, functional practitioner, and founder of Vibrant Blue Oils, where she has combined her training in nutritional therapy and aromatherapy to create unique proprietary blends of organic and wild-crafted essential oils. She has helped over 50,000 clients heal from brain-related challenges, including anxiety, insomnia, and autoimmunity. For the past ten years, she has lectured at wellness centers, conferences, and corporations on brain health, essential oils, stress, and detoxification. She has been seen in The New York Times, Wellness Mama, Elephant Journal, and numerous publications. Her website, vibrantblueoils.com, is visited by over 300,000 natural health seekers every year, and she has rapidly become a top resource for essential oils education on the Internet today. Connect with Cynthia Thurlow On Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Jodi Cohen Vibrant Blue Oils  On Instagram Facebook Use the coupon code WELCOME 10 for $10 off anything you purchase from the Vibrant Blue Oils Shop Jodi’s book, Essential Oils to Boost the Brain and Heal the Body, is available on Amazon and most anywhere books are sold.

I am delighted to have the honor of connecting with Calley Means today. Calley is the Founder of Truemed, a company that facilitates tax-free spending on food and exercise. He also co-authored a book with his sister, Casey Means, called Good Energy, to be released later this year.  Calley graduated from Stanford and Harvard Business School. He was a consultant for food and pharmaceutical firms and now exposes their tactics to weaponize our trusted institutions. In our conversation today, Calley and I examine the impact of drug utilization, including GLP 1s, on obese children and discuss the relevance of his background in food and pharmaceuticals and the problem of treating obesity as a disease. We dive into the role of food stamps and subsidies and look at ways we can help improve food quality in the United States and reduce the influence of the pharmaceutical industry, also addressing conflicts of interest between the NIH and universities, the effects of reduced subsidies and processed food consumption on families, and dopamine regulation.  This conversation has been long-awaited, and as a dedicated fan of Calley's work, I am thrilled to share it with you. IN THIS EPISODE YOU WILL LEARN: Calley highlights the conflicts of interest in obesity research and the ineffectiveness of the US healthcare system in addressing chronic obesity in children. How the pharmaceutical industry prioritizes profit over health Why the American health crisis is not only a medical problem but also a moral issue The influence of processed food companies on nutritional research The crucial need to address the root causes of chronic diseases How the influence of pharmaceutical lobbyists corrupts Congress The growing distrust in American institutions  How nutrition research funding impacts US food guidelines The challenges of raising children when processed foods get weaponized to hook people Calley discusses his upcoming book, Good Energy, and explains how his company, Truemed, helps patients unlock tax-free spending on metabolically healthy items. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Calley Means On his website Truemed website Instagram Twitter

Today, I am delighted to connect with Caroline Alan, the Co-founder and CEO of Beam Minerals.  Coming from the corporate world, Caroline struggled until she discovered the incredible ability of plant-based minerals to support the body and restore its natural balance. She is now devoted to educating people about the benefits of mineral replenishment and the efficacy of plant-based humic and fulvic substances. In today’s discussion, Caroline shares her journey, and we dive into why we experience such significant mineral depletions in our modern-day lifestyles, looking at hidden hunger and the role of our mitochondria. We discuss the interrelationship between mineral storage and adrenal health, the extensive background of plant-based minerals, and the etiology of cramps and hydration. We also explore the signs and symptoms of mineral depletion and explain how to take mineral products for the best results. Join us to learn about the transformative power of plant-based minerals in our modern lives. IN THIS EPISODE YOU WILL LEARN: Why so many people experience mineral depletion at this time How soil health, food quality, and human health are all interrelated The fundamental role mitochondrial function plays in energy production and overall health Why adrenal health is critical for women during perimenopause and menopause The origins of humic and fulvic minerals How fulvic and humic acids help in preventing chronic diseases Why Caroline advocates for using fulvic acid products instead of salt-based electrolytes Caroline shares tips for managing Herxheimer reactions How do mineral deficiencies impact sleep and exercise performance? The benefits of magnesium spray for foot cramps and plantar fasciitis Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Caroline Alan On the Beam Minerals website  Find Beam Minerals on social media @beamminerals Caroline on social media @themineralgeek

I am honored to connect with Dr. Susan Peirce Thompson today. Dr. Peirce Thompson is an adjunct associate professor of Brain and Cognitive Sciences at the University of Rochester and an expert in the psychology of eating. She is also the New York Times bestselling author of Bright Line Eating. In our conversation today, we dive into the complexities of food addiction, exploring why it is even more challenging than drug or alcohol addiction, the importance of awareness around food addiction, and the impact of genetics and trauma. We discuss the addictive properties of sugar and flour, the bliss point in the processed food industry, and misconceptions surrounding artificial sugars. Dr. Peirce Thompson also shares her journey of addiction and recovery, offering invaluable insights on breaking the cycle of addiction and reframing our relationship with hunger.  I am confident that today’s discussion with Dr. Susan Peirce Thompson will provide valuable insights and provoke thoughtful reflections. Join us to learn how to break the cycle of addiction and reclaim control over your relationship with food. IN THIS EPISODE YOU WILL LEARN: Why food addiction is more challenging to treat than other addictions What are the signs of food addiction? The role of genetics in obesity and food addiction How trauma can lead to food addiction Why hyper-palatable processed foods are so addictive How sugar impacts the brain Why it is best to avoid high fructose corn syrup and all artificial sugars How food companies use the bliss point to make their products addictive Why structured eating is essential in modern society Why hunger is not an emergency Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Susan Peirce Thompson Bright Line Eating

I am honored to reconnect with Dave Feldman today. Our last encounter was in December 2020, for Episode 128, where we delved deeply into the topic of cholesterol. Dave is an engineer by profession. He is profoundly clever and commands great respect within the low-carb and keto community due to his willingness to challenge prevailing narratives, encouraging us to explore alternative perspectives on lipid metabolism and reconsider our understanding of LDL, particularly in the context of lean mass hyper-responders like myself. In our discussion today, we dive into how LDL became so vilified, with Dave shedding light on several crucial research findings. We explain what low-mass hyper-responders are, examine biases and cognitive dissonance, touch on Dave’s new LMHR study, and discuss the Miami Heart study, a longitudinal study of the roles of LDL and plaque burden. We also explore the impact of ApoB and reflect on the essence of science as a pursuit of truth, and Dave shares what lies ahead for himself and his research. I trust you will find this conversation engaging and thought-provoking. IN THIS EPISODE YOU WILL LEARN: Why LDL is considered a villain  How AMRs and APB lipoproteins have influenced how we look at risk stratification What is a lean mass hyper-responder? How a low-carb, high-fat diet can improve the metabolic health of lean mass hyper-responders How Dave, an engineer turned scientist, challenges conventional wisdom in the health and wellness space Dave discusses a study on plaque progression in healthy individuals, focusing on correlating LDL levels  How we are at the forefront of finding the significance of lean mass hyper-responders and LDL Dave shares the next thing he and his team will look at to substantiate his findings on lean mass hyper-responders Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dave Feldman On his website Instagram X     Facebook Previous Episode Mentioned Ep. 128 – Cholesterol Obsession: Why It’s the Intellectual Property of the Animal Kingdom with Dave Feldman

I am delighted to have Dr. Colleen Cutcliffe, the CEO and Co-founder of Pendulum, joining me today.  Dr. Cutcliffe is a proud alumnus of Johns Hopkins, with over 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotech. Before starting Pendulum, she was the Senior Manager of Biology at Pacific Biosciences and a scientist at Elan Pharmaceuticals.  In our discussion today, we dive into the emerging science of the gut microbiome, examining the effects of aging, antibiotics, nutrition, stress, travel, and menopause on gut health and discussing how vaginal and C-section deliveries differ in impact. We explore differentiators for various categories of bacteria and the roles of butyrate and fiber, looking at fecal transplants and the difference between probiotics, prebiotics, and post-biotics, and explaining why Akkermansia is an essential bacteria for regulating insulin satiety, fortifying the mucin layer, and facilitating targeted delivery of butyrate. Dr. Cutcliffe also shares her top tips for mitigating the effects of travel on the gut microbiome and offers a special discount for listeners.  I am confident that you will find today’s discussion with Dr. Colleen Cutcliffe engaging and enlightening. Stay tuned to learn how to adjust your lifestyle for a healthier gut microbiome. IN THIS EPISODE YOU WILL LEARN: The benefits of a vaginal delivery Various factors that disrupt the gut microbiome Why it is essential to get enough fiber in your diet What are the signs and symptoms of an unhealthy gut microbiome? The benefits of fecal transplants How the vagus nerve fosters communication between the gut and brain Why artificial sweeteners might not be as harmful to the gut microbiome as previously thought How prebiotics, probiotics, and postbiotics are interconnected and necessary for overall health The role of Akkermansia in the gut microbiome How to maintain a healthy gut microbiome while traveling   Bio: Dr. Colleen Cutcliffe: Colleen Cutcliffe, PhD, is the CEO and Co-Founder of Pendulum. She has over 25 years of experience leading and managing biology teams in academia, pharmaceuticals, and biotechnology. Before starting Pendulum, Colleen was the Senior Manager of Biology at Pacific Biosciences and a Scientist at Elan Pharmaceuticals. Colleen received her Ph.D. in Biochemistry and Molecular Biology from Johns Hopkins University and her B.A. in Biochemistry from Wellesley College. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Colleen Cutcliffe On the Pendulum Life website Use code THURLOW for 20% off your first order of Pendulum products.

Today, I have the honor of connecting with Juraj Kocar, the CEO of Somavedic Technologies. Somavedic is a groundbreaking frequency therapy device providing practical and easily accessible solutions for EMF exposure, improved sleep, and energy revitalization.  Juraj is a perpetually optimistic and forward-thinking entrepreneur motivated by a profound passion for developing and expanding products that significantly impact the lives of others, and he is currently propelling his dream project to new levels of success. In our discussion today, we meticulously define the role of EMFs, diving into how they affect our health, discussing proactive protection measures, and sharing strategies for mitigating EMF exposure while traveling. We also explore how the revolutionary Somavedic device works, my experience using it, how to choose the correct model, the effects of structured water, and biohacking strategies that Juraj uses daily. Join us for an enriching conversation where we provide valuable insights and practical strategies to enhance your health. IN THIS EPISODE YOU WILL LEARN: What are EMFs? Juraj discusses the biological effects of chronic EMF exposure How to protect yourself from or minimize the impact of EMF exposure How to deal with EMF exposure when traveling Juraj explains how the Somavedic technology works What structured water is  Why it is beneficial for us to drink structured water Juraj discusses his daily health routine  Strategies for improving your health How to select the Somavedic device that best suits your needs Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Juraj Kocar On his website *Get a 10% discount on Somavedic products by using the code CYNTHIA (Discount code is valid all year long!) On Instagram Via email: hello@somavedic.com

Dr. Thomas Dayspring is certified in internal medicine and clinical lipidology. He is a fellow of the American College of Physicians and the National Lipid Association. He joins me today for the second class in our series of Lipid Masterclasses.   In today’s class, Dr. Dayspring shares valuable insights on cardiovascular health and lipid management. We dive into the complexities of cardiovascular disease, focusing on lipoproteins, atherogenesis progression, and its implications on myocardial infarctions (heart attacks). He explains the mechanisms of ApoB invasion into arterial walls and discusses the critical importance of finding competent healthcare providers, particularly for women navigating the perimenopausal to menopausal transition. He also gets into the limitations of bikini medicine, and we tackle pertinent issues surrounding hormone replacement therapy, including potential side effects and clinical observations.  Dr. Dayspring has a wealth of information to share today, and we have several additional masterclasses coming up to follow this class. Be sure to tune in for those episodes. IN THIS EPISODE YOU WILL LEARN: How lipids get transported, and how energy gets produced in the body How the liver prevents fatty liver tissue from building up Dr. Dayspring explains the process of lipolysis   What is the role of LDL particles in atherosclerosis? How the buildup of plaque in arteries can lead to blockages, causing heart attacks or strokes if left untreated Why high cholesterol needs to get diagnosed and treated as early as possible  The importance of HDL cholesterol in immunity and oncogenesis Why ApoB is essential for lipid panel analysis Why women need comprehensive medical care, especially during menopause Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring Twitter (@DrLipid) LinkedIn

Today, I am delighted to reconnect with Dr. Sara Gottfried, a board-certified physician practicing evidence-based integrative precision and functional medicine. (She last joined me for Episode 211.) Dr. Gottfried graduated from Harvard and MIT. She is a Clinical Assistant Professor in the Department of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University and the Director of Precision Medicine at the Marcus Institute of Integrative Health. She is also the author of four New York Times best-selling books, including her recent publication, The Autoimmune Cure.  In our discussion today, we discuss the interrelationship between trauma and autoimmunity, highlighting its prevalence, particularly among women. We dive into the impact of trauma, explaining its correlation with autoimmune conditions and demystifying the role of the PINE network (the Psycho Immune Neuro Endocrine system). We explore triggers for perimenopause and menopause, gender differences specific to the changes in immunity and vulnerability in women, the consequences of burnout in various professions, the shortcomings of conventional allopathic methods in addressing mental health and trauma, and immunomodulation, including vitamins, polyphenols, low-dose Naltrexone, and somatic-based therapies.  With Dr. Gottfried’s invaluable insights into crucial health topics, this episode is a must-listen. Stay tuned for more! IN THIS EPISODE YOU WILL LEARN: How the traumas we experience as children could make us more susceptible to autoimmune conditions later in life How trauma impacts our immune, neurological, and endocrine systems Addressing trauma through gut health, heart rate variability, and hormone balance How the metabolic and immune system changes triggered during perimenopause and menopause can make women more susceptible to autoimmune issues  How men in combat and women with sexual assault show similar trauma responses  How childhood trauma can shape our direction in life The potential benefits of alternative therapies like LSD, MDMA, and Ayahuasca How measuring gut health can provide valuable insights for treatment options Using low-dose Naltrexone for sleep and immune system modulation The potential of somatic therapies and breathwork for stilling the autonomic nervous system and promoting body awareness Bio: Dr. Sara Gottfried: Sara Szal Gottfried, MD, is a physician, researcher, author, and educator. She graduated from Harvard Medical School and MIT and completed a residency at UCSF, but is more likely to prescribe a CGM and personalized nutrition plan than the latest pharmaceutical. Dr. Gottfried is a global keynote speaker and the author of four New York Times bestselling books about hormones, nutrition, and health. Her latest book is called THE AUTOIMMUNE CURE (March 2024). She is a Clinical Assistant Professor in the Dept. of Integrative Medicine and Nutritional Sciences at Thomas Jefferson University and Director of Precision Medicine at the Marcus Institute of Integrative Health. She takes care of executives and professional athletes. Her focus is on the interface of mental and physical health, N-of-1 trial design, personalized molecular profiling, use of wearables, and how to leverage these tools to improve health outcomes.  Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Sara Gottfried On her website    On Instagram Dr. Gottfried’s new book, The Autoimmune Cure, is available from most bookstores, including Amazon and Barnes and Noble. Previous Episode Mentioned Ep. 211 – Addressing the Root Cause of Hormonal Imbalances with Dr. Sara Gottfried

I am delighted and honored today to interview Dr. Lisa Mosconi. She is an Associate Professor of Neuroscience in neurology and radiology at Cornell Medicine and Director of the Women's BRAIN Initiative and the Alzheimer's Prevention Clinic at Weill Cornell Medicine, New York Presbyterian Hospital. She is also a globally acclaimed neuroscientist with a Ph.D. in neuroscience and nuclear medicine and the author of the New York Times bestseller The XX Brain and, more recently, The Menopause Brain. In our conversation, we discuss how women’s brains change during perimenopause and menopause, looking at the significance of puberty, pregnancy, and perimenopause, as well as the lack of medical research on women and medical gaslighting. We explore the concept of bikini medicine and its misconceptions regarding women's health and hormones alongside the crucial roles of hormones like estradiol, progesterone, and testosterone in our neuroendocrine system. Dr. Mosconi also provides insights into evolving menopausal treatments, including lifestyle interventions.  Dr. Mosconi is an esteemed figure in neuroscience and a prominent voice in women's health. I am confident you will gain valuable insights and perspectives from my discussion with her today. IN THIS EPISODE YOU WILL LEARN: How women's brains change during perimenopause and menopause How the lack of information for young girls can lead to medical gaslighting and confusion during perimenopause Dr. Mosconi explains how a simple sugar is used as a tracer to track glucose metabolism in the brain during perimenopause Why brain changes during menopause may lead to mental fatigue and brain fog How the lack of training and research on menopause in medical residency programs leads to a poor understanding among clinicians Why women need to consider their brain and metabolic health during perimenopause Why estrogen is essential after menopause The benefits of HRT for menopausal women How stress impacts hormone production Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Lisa Mosconi On her website On Instagram The Menopause Brain will be released March 12th, 2024.

Today's episode is a true gem! I am thrilled to introduce Craig Siegel, the Wall Street Journal and USA Today Best Selling Author of The Reinvention Formula. Craig is recognized globally as a keynote speaker, TEDx speaker, and host of the CLS Experience Podcast, where he has conversed with some of the most influential figures in the world. Having the privilege of being a guest on his show in 2023, I am delighted to have Craig joining me today to share his remarkable insights and discuss his inspiring journey.  In our conversation today, Craig shares how the pandemic became a catalyst for his evolution, which he refers to as his global awakening. We explore the importance of setting audacious goals and the transformative power of vulnerability. We also look into neuro-linguistic programming and clarify how it can cultivate confidence and reframe your mindset. We also discuss the role of adversity, ego dynamics, and why service implies love, and creates a lasting legacy. This conversation will infuse your year with invaluable wisdom, and I look forward to additional collaborations with Craig going forward.  Stay tuned for more! IN THIS EPISODE YOU WILL LEARN: How the pandemic restructured Craig’s life and helped him redefine himself Craig shares his journey of embracing vulnerability and authenticity The benefits of having bold, fearless, and audacious goals How being willing to look silly or make mistakes can lead to success How mindset influences growth, both personally and professionally How neuro-linguistics can reprogram belief systems The power of choice and imagination for creating positive change Why it is essential to align your decisions with your personal and professional goals rather than being driven by ego Why building a community based on mutual support and collaboration is even more important than building an audience How authentic conversations can lead to inspired action Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Connect with Craig Siegel On his website Instagram The CLS Experience Podcast Craig's Book The Reinvention Formula is available on Amazon and most anywhere books are sold. For free inspirational messages throughout the week, text Craig at 917-634-3796 using the code CYNTHIA and share your favorite nugget from today’s conversation.

Today, I am delighted to reconnect with two previous guests, Dr. Darren Candow. Dr. Candow is a distinguished professor and an internationally renowned researcher on creatine monohydrate, nutrition, and physical activity who joined me before on Episode 301, where we spoke about creatine.  We are doing an AMA session today, delving into various themes surrounding creatine, from debunking outdated RDA recommendations to exploring the synergies between strength training and creatine efficacy. We look into the cognitive benefits of creatine, exploring how it interacts with caffeine and its implications for bone health, hydration, anabolic resistance, and metabolic health.  I trust you will find today's AMA session as enlightening and enriching as I did while recording it. IN THIS EPISODE YOU WILL LEARN: The safety and efficacy of creatine as a supplement How creatine increases muscle mass and reduces protein catabolism The benefits of combining creatine with protein  Is it better to take creatine before or after a workout? How creatine supplementation may improve brain performance and mental clarity Why exercise is essential for those who want to experience the benefits of creatine for maintaining their bone health The benefits of resistance-band workouts for post-menopausal women Are there any age-related limits for creatine supplementation? Bio: Dr. Darren Candow Dr. Darren Candow, PhD, CSEP-CEP, is Professor and Director of the Aging Muscle and Bone Health Laboratory in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. The overall objectives of Dr. Candow’s research program are to develop effective lifestyle interventions involving nutrition (primarily creatine monohydrate) and physical activity (resistance training), which have practical and clinical relevance for improving musculoskeletal aging and reducing the risk of falls and fractures. Dr. Candow has published over 120 peer-refereed journal manuscripts, supervised over 20 MSc and PhD students, and received research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, the National Institute of Health, and the Nutricia Research Foundation. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition, Nutrients, and Frontiers. Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Darren Candow On Instagram and Twitter (now X) Previous Episode Mentioned: Ep. 301 Creatine: The Best Supplement for Better Bones & Brain Health with Darren Candow, PhD, CSEP-CEP

Today, I have the privilege of engaging with Kashif Khan. Kashif is the author of The DNA Way. He is also a two-time TEDx speaker, a celebrity longevity coach, and Founder of The DNA Company, an innovative company at the forefront of personalized medicine that has leveraged unique insights into the human genome.  In our conversation today, we dive into the impact of our current healthcare system and share daily practices to help men and women enhance their longevity. We discuss the genome, considerations for bio-individuality and genetics, and how mood and behavior impact our overall well-being. Kashif also addresses some issues women face in midlife, including sleep problems, weight loss resistance, and bone health.  I am sure anyone seeking a deeper understanding of these matters will find our discussion significant and most valuable. IN THIS EPISODE YOU WILL LEARN: How the focus of our current healthcare system is on symptom management, not prevention The fundamental principles of the 2018 Harvard study on five practices that every male and female can do to live longer Kashif explains how his company created a tool to make genetic testing more accessible and personalized  Why personalization in healthcare is so important How dopamine pathways affect the perception of pleasure and reward The symptoms of serotonin dysregulation Sleep disruptions and circadian rhythm in perimenopause and menopause How circadian rhythm disruptions can lead to sleep problems How our emotional intelligence impacts our ability to connect and empathize with others How broken detox pathways can lead to inflammation and disease How hormone dominance affects menopause, weight loss, and overall health Bio: Kashif Khan is the author of The DNA Way, a two-time TedX Speaker, Celebrity longevity coach, and Founder of The DNA Company, where personalized medicine is being pioneered through unique insights into the human genome. Growing up in Vancouver, Canada in an immigrant household, Kashif developed an industrious entrepreneurial spirit from a young age. Before his tenure at the DNA Company, Kashif advised several high-growth start-ups in a variety of industries. As Kashif dove into the field of functional genomics as the Founder of The DNA Company, it was revealed that his neural wiring was genetically designed to be entrepreneurial. However, his genes also revealed a particular sensitivity to pollutants. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Kashif Khan On Instagram On his website   Go to Kashif’s special landing page   The DNA Company

Today, I have the privilege of connecting with Dr. Nicole LePera, the Holistic Psychologist.  Dr. LePera did her clinical psychology training at Cornell University. She has touched the lives of countless individuals seeking growth and transformation through her popular Instagram account and has written several self-help books, including How to Do the Work and How to Be the Love You Seek.  In our discussion today, we dive into the current impact of our childhood experiences, exploring crises of faith, the dark night of the soul, inner child archetypes, and shame. Dr. LePera sheds light on the dynamics of dysfunctional patterns, triggers, and regression while also examining the role of generational and systemic beliefs, trauma, and the emerging science of heart-brain coherence and heart rate variability, sharing practical tips for cultivating presence in our bodies to assist us in processing our emotions. Dr. LePera's work has been profoundly instrumental in my personal development journey, and I know you will find our conversation enlightening and enriching.  IN THIS EPISODE YOU WILL LEARN: How the subconscious mind determines our habits and relationships Dr LePera explains the concept of the dark night of the soul The importance of examining your conditioned behaviors and reconnecting with your true identity  How inner child archetypes impact behavior Why is self-development essential? How our past experiences shape the way we perceive and interpret current events The benefit of embodiment practices for developing emotional tolerance How childhood trauma impacts physical and mental health The impact of intergenerational trauma on mental health How to achieve heart coherence Dr. LePera shares mindfulness practices for stress management and self-awareness Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Nicole LePera On her website How to Be The Love You Seek  On Instagram, YouTube, TikTok, and X

Today, I have the pleasure of connecting with Dr. Sue Varma. Dr. Varma is a privately-practicing board-certified psychiatrist and a Clinical Assistant Professor of Psychiatry at New York University. She is a nationally acclaimed keynote speaker, medical contributor, media consultant, and advisor to leading television networks and programs. In our discussion today, we examine the impact of shared life experiences like 9/11 and the pandemic, exploring the role of PTSD and the effects of practical optimism, self-care, and self-reliance. We discuss optimism, its inheritability, and the significance of milestones for women, including transitioning from high school to college, navigating midlife, and addressing feelings of loneliness. We also look into purpose and compassion, the complexities of processing emotions, the challenges of the perfectionism façade, the role of trauma, ACE scores, autoimmunity, and the benefits of mindfulness and meditation.  Stay tuned for more! IN THIS EPISODE YOU WILL LEARN: Dr. Varma discusses the collective sense of grief, fear, connection, and empathy after 9/11 and the pandemic The importance of optimism and resilience when dealing with tragedy How Dr. Varma helps her patients identify their blind spots and other areas for improvement in their lives How perimenopause can bring about a sexual awakening and increased desire for intimacy but also loneliness and dissatisfaction in relationships Why friendships are essential for our well-being Why do we need to invest in different types of connections and relationships? The critical importance of finding purpose in life  How unprocessed emotions affect our mental and physical well-being How trauma impacts mental health Some practical tips for incorporating mindfulness into daily life  The benefits of meditation Bio: Dr. Sue Varma is a board-certified psychiatrist in private practice and a Clinical Assistant Professor of Psychiatry at New York University (NYU) Langone Health. She is a Distinguished Fellow of the American Psychiatric Association. Dr. Varma was the first medical director and attending psychiatrist at the World Trade Center Mental Health Program at NYU Langone Health, treating civilians and first responders in the aftermath of 9/11. Dr. Varma is a nationally acclaimed keynote speaker, medical contributor, media advisor, and consultant to major networks and shows. She regularly appears on the Today Show, Nightly News, CBS Mornings, and Good Morning America and is frequently interviewed by Time, Washington Post, NPR, and beyond. Dr. Varma is the recipient of numerous prestigious awards for her ground-breaking efforts in mental health education and advocacy, including a Sharecare Emmy. Her forthcoming book, “Practical Optimism,” is eagerly anticipated worldwide, with translations in several languages. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Sue Varma On her website Instagram Facebook Twitter LinkedIn Dr. Varma's book, Practical Optimism:  The Art, Science, and Practice of Exceptional Well-Being