From Slate comes the Big Mood, Little Mood with Daniel M. Lavery advice podcast. From 2016 to 2021, Lavery wrote Slate's popular online advice column, Dear Prudence. He shares his wisdom and wit on this show.

Lavery is a trans man and has explained his journey over the years to his readers and listeners. Many of the letters he receives involve gender issues. How can listeners get people to respect their pronouns? What's the best way to handle estrangement from mom and dad? No matter the topic, Lavery and the guests will provide insight and personal experience to help. Lavery is a trans man and has explained his journey over the years to his readers and listeners.

Lavery welcomes comedians, authors, celebrities, and experts in various industries. His guests often read listener letters first. Then, they share their advice with listeners before starting their interviews. Lavery explores conversations about health with guests like author Aubrey Gordon. New York Times bestselling author Celeste Ng reads listeners' letters and talks about her books.

Lavery doesn't have a cohost for the show. But he creates a comfortable dialogue with his guests, so the episodes are engaging. This podcast is a unique approach to an advice column mixed with an interview-style show.