Join us this episode as we discuss new recommendations from the American Dental Association on acute pain management. The GameChangerDosing acetaminophen and ibuprofen where they peak at the same time due to their synergistic properties, resulting in treatment being often more effective than hydrocodone-apap and oxycodone-apap for pain relief. GuestKaren Baker, M.S.Pharm., R.PhAssociate ProfessorColleges of Dentistry and Pharmacy, University of Iowa Referencehttps://www.ada.org/about/press-releases/new-guideline-details-acute-pain-management-strategies-for-adolescent-adult-dental-patients Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss new guideline details on acute pain management for dental patients.2. Identify how appropriate prescribing for acute dental pain can improve treatment and outcomes.0.05 CEU/0.5 HrUAN: 0107-0000-24-157-H01-PInitial release date: 04/22/2024Expiration date: X/042/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Shortages, access, and cost have led to compounding GLP1s, which has created confusion and misinformation for patients and healthcare providers. Join us as we discuss this practice and delve into what you need to know as a healthcare provider.THE GAMECHANGER: The advent of GLP1s is a true GameChanger in the health of patients with diabetes, cardiovascular diseases, and obesity, and has led to access issues for manufactured products. GuestsTenille Davis, PharmD, RPhChief Advocacy OfficerAlliance for Pharmacy CompoundingScott Brunner, CAECEOAlliance for Pharmacy CompoundingHostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health Referencehttps://a4pc.org/advocacy/educating-prescribers/https://a4pc.org/advocacy/statements-and-other-resources/https://a4pc.org/files/APC-Compounded-GLP-1s-Media-Brief-REVISED-March-2024.pdf Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Review criteria for compounding drugs on the FDA drug shortage list. 2. Discuss the facts and misinformation surrounding compounded GLP1 medications.0.05 CEU/0.5 HrUAN: 0107-0000-24-145-H01-PInitial release date: 04/15/2024Expiration date: 04/15/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

This episode discusses the 2023 Inflation Reduction Act and HHS's authority to negotiate prices for high-cost drugs in Medicare Part D. In addition to the initial list of 10 drugs, HHS is now focused on medications used in the hospital and covered under Medicare Part B. The GameChangerHHS updates the Inflation Reduction Act that will impact over 750, 000 people. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthJake Galdo, PharmD, MBA, BCPS, BCGPCEOSeguridadReferencehttps://www.cms.gov/files/document/reduced-coinsurance-certain-part-b-rebatable-drugs-april-1-june-30-2024.pdf https://www.hhs.gov/about/news/2024/03/26/hhs-announces-savings-41-prescription-drugs-thanks-inflation-rebates-from-biden-harris-administrations-lower-cost-prescription-drug-law.html?utm_source=MarketingCloud&utm_medium=email&utm_campaign=PT+Daily+March+27&utm_content=PT+Daily+March+27Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the monetary impact of the Inflation Reduction Act.2. Discuss how the Medicare Part B drug addition will benefit patients.0.05 CEU/0.5 HrUAN: 0107-0000-24-136-H04-PInitial release date: 4/08/2024Expiration date: 04/08/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

This episode discusses quality and value in healthcare and how the BPCI program, designed to lower costs and enhance care quality, particularly in the post-acute phase, did not demonstrate notable positive impacts on HF-related measures. What does this mean for the larger health quality landscape? The GameChangerQuality in healthcare is rapidly evolving. There are pressures at the population level that evaluate how we do things; the quality always needs to be safety focused.HostJake Galdo, PharmD, MBA, BCPS, BCGPCEOSeguridad ReferenceArticle: Bundled Payments for Care Improvement and Quality of Care and Outcomes in Heart Failurehttps://jamanetwork.com/journals/jamacardiology/article-abstract/2813066  Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Define quality in healthcare.2. Review outcomes of hospitals participating in the BPCI program.0.05 CEU/0.5 HrUAN: 0107-0000-24-133-H04-PInitial release date: 04/01/2024Expiration date: 04/01/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

The anti-rejection drug rapamycin has been shown in mice and other mammals to reverse cellular damage caused by aging to extend healthy life by up to 20%. This has caused massive off-label prescribing and use of rapamycin in humans as an anti-aging drug.  The GameChangerWhat do you tell patients about the evidence-based use of rapamycin for anti-aging? HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health Referencehttps://www.washingtonpost.com/business/2024/03/15/rapamycin-longevity-drug/https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00258-1/fulltext Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the mechanism of action of rapamycin and how it may reverse normal aging.2. Discuss the current state of evidence of rapamycin for this indication and its safety concerns.0.05 CEU/0.5 HrUAN: 0107-0000-24-129-H01-PInitial release date: 03/25/2024Expiration date: 03/25/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

In this episode, we delve into the crucial topic of understanding generational differences in the context of pharmacy education. Our guest expert, Melissa Medina from the University of Oklahoma, brings a wealth of knowledge and experience to the table, shedding light on why grasping these generational nuances is paramount for preceptors working with pharmacy students and residents.Tune in to gain a fresh perspective on how everyone can win and learn by engaging across generations.  HostKathy Schott, PhDVice President, Education & OperationsCEimpactGuestMelissa Medina, Ed.DInterim Dean and ProfessorThe University of Oklahoma Health Sciences Center College of PharmacyGet CE: CLICK HERE TO GET CPE CREDIT FOR THE COURSE!CPE Information Learning ObjectivesAt the end of this course, preceptors will be able to:Describe factors that have impacted how Generation Z p(Gen Z) pharmacy residents and student pharmacists see the world.Identify strategies for engaging effectively with Gen Z learners.0.05 CEU/0.5 HrUAN: 0107-0000-24-111-H99-PInitial release date: 3/20/2024Expiration date: 3/20/2027Additional CPE details can be found here.The speakers have no relevant financial relationships with ineligible companies to disclose.ChatGPT 3.5 (https://chat.openai.com) was utilized in the planning of this P2P episode.This program has been:Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors.Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors.Follow CEimpact on Social Media:LinkedInInstagram

The GameChangerA new study looks at the utility of omalizumab in preventing food allergy reactions after accidental exposure. ACEis and Beta-blockers should be avoided in patients with recurrent anaphylaxis if possible. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceStudy: https://www.nejm.org/doi/full/10.1056/NEJMoa2312382 Anaphylaxis guideline: https://www.annallergy.org/article/S1081-1206(23)01304-2/fulltext Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the OUtMATCH study results and their relevance to patients with food allergies.2. Interpret the new AAAAI anaphylaxis guidelines in relation to patient care.0.05 CEU/0.5 HrUAN: 0107-0000-24-079-H01-PInitial release date: 03/18/2024Expiration date: 03/18/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Stay updated on recently FDA-approved medications crucial for pharmacists. Gain essential insights on new drugs approved in the last 12 to 18 months, ensuring accurate dispensing and effective patient education. The GameChangerSweatControl Patch approved for primary axillary hyperhidrosis.Update in treatment for Alzheimer's with mild cognitive impairment. HostJoe Strain, PharmDClinical Faculty, Monument HealthSouth Dakota State College of Pharmacy  Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the therapeutic indications of recent FDA-approved medications.2. Describe unique pharmacological properties for each new medication. 0.05 CEU/0.5 HrUAN: 0107-0000-24-098-H01-PInitial release date: 03/11/2024Expiration date: 03/11/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

The cardiometabolic syndrome is a concept recently developed by the American Heart Association to denote the totality of risk in a patient with risk factors that may lead to or worsen chronic kidney disease or cardiovascular events. A new validated scoring system has been endorsed by AHA to better assess the short and long-term risk for these in the general population.  We will discuss this scoring system in this podcast.The GameChangerA new validated scoring system has incorporated factors to better determine the 10 and 30 year risk of CVD and CKD in a general population.Geoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthMathew Boyd, PharmDClinical PharmacistUnity Point ReferenceGuidelines: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001191Calculator: https://professional.heart.org/en/guidelines-and-statements/prevent-calculator Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the concept of the Cardiovascular-Kidney-Metabolic syndrome. 2. Discuss how the PREVENT scoring system is applied to patients. 0.05 CEU/0.5 HrUAN: 0107-0000-24-075-H01-P  Initial release date: 3/4/2024Expiration date: 3/4/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Several outbreaks of a relatively new, resistant fungal infection - candida auris - have been reported in the Pacific Northwest. It is highly contagious and its mortality has approached 60%. Listen in as we discuss what to watch for and how to prepare if this reaches your geography.THE GAMECHANGER: Candida auris is resistant to most antifungals, has high plasticity, and its mortality approaches 60%.Geoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceCristina ML, Spagnolo AM, Sartini M, Carbone A, Oliva M, Schinca E, Boni S, Pontali E. An Overview on Candida auris in Healthcare Settings. J Fungi (Basel). 2023 Sep 8;9(9):913. doi: 10.3390/jof9090913. PMID: 37755021; PMCID: PMC10532978. Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss characteristics of C. auris infections that make it difficult to avoid outbreaks 2. Describe issues surrounding treatment of serious infections with C. auris 0.05 CEU/0.5 HrUAN: 0107-0000-24-058-H01-PInitial release date: 2/26/2024Expiration date: 2/26/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Do you feel like it is getting more difficult to engage your students or residents on your rotation and keep them engaged? Or maybe you personally feel a little bored with the same old activities and strategies. In this episode, preceptors Beth Cady and Carrie Vogler of Southern Illinois University Edwardsville on some creative strategies they use to engage their learners. Kathy Schott, PhDVice President, Education & OperationsCEimpactKate Newman, PharmDDirector of Experiential EducationSouthern Illinois University EdwardsvilleElizabeth Cady, PharmDClinical Associate ProfessorSouthern Illinois University EdwardsvilleCarrie VoglerClinical ProfessorSouthern Illinois University EdwardsvilleGet CE: CLICK HERE TO CPE CREDIT FOR THE COURSE!CPE Information Learning ObjectivesAt the end of this course, preceptors will be able to:1. Discuss barriers to effectively engaging students and residents in their experiential learning 2. Identify creative strategies for engaging students and residents to optimize their learning0.075 CEU/0.75 HrUAN: 0107-0000-24-059-H99-P Initial release date: 2/21/2024Expiration date: 2/21/2027Additional CPE details can be found here.The speakers have no relevant financial relationships with ineligible companies to disclose.ChatGPT 3.5 (https://chat.openai.com) was utilized in the planning of this Precept2Podcast episode.This program has been:Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors.Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors.Follow CEimpact on Social Media:LinkedInInstagram

With pockets of measles outbreaks throughout the country, we discuss the reasons and strategize ways pharmacy can impact vaccination rates in their communities.  The GameChangerMeasles was essentially eliminated from the US in 2000. Now, we are seeing a resurgence of outbreaks that have prompted the CDC to issue warnings and reminders of the importance of proper vaccination.  Geoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthElizabeth Skoy, PharmDProfessorNorth Dakota State UniversityLacy Epperson, PharmD Clinical Pharmacist Mitchell’s Drug Store Referencehttps://www.usatoday.com/story/news/health/2024/01/26/cdc-issues-alert-measles-global/72365871007/ Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the CDC warning about the increased incidence of measles 2. Discuss ways pharmacy can have an impact on increasing vaccination rates and decreasing measles outbreaks 0.05 CEU/0.5 HrUAN: 0107-0000-24-057-H01-P Initial release date: 2/19/2024Expiration date: 2/19/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

With record-cold temperatures in much of the United States this winter, a high number of cold injuries have been reported. This podcast discusses prevention and treatment for hypothermia and frostbite. Brrrrr! The GameChangers: Frostbite prevention using layers and heating measuresHypothermia treatment using external and internal heating Frostbite treatment with anticoagulants HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health Referencehttps://www-nejm-org./doi/10.1056/NEJMra1800868?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Differentiate between types of hypothermia2. Discuss treatments for frostbite0.05 CEU/0.5 HrUAN: 0107-0000-24-051-H01-P Initial release date: 2/12/2024Expiration date: 2/12/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

The American Diabetes Association has released the 2024 Standards of Care for people with Type 1 and Type 2 Diabetes. Join us as we talk with one of our favorite diabetes experts, Dr. Sue Cornell, about the major shifts in diabetes care that are omnipresent in this year's guideline updates.  The GameChangerDiabetes treatment is shifting to prevention and delay. After a long period of time without many advances, we are now on the brink of changing the game in diabetes care and prevention with new drugs and technologies.  HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthSusan Cornell, PharmD, CDCES, FAPhA, FADCESDiabetes Care & Education SpecialistMidwestern University College of Pharmacy  Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss highlights of the 2024 American Diabetes Association Standards of Care Update 2. Describe the landscape of diabetes care as it shifts to prevention and delay0.05 CEU/0.5 HrUAN: 0107-0000-24-050-H01-PInitial release date: 2/5/2024Expiration date: 2/5/2025Additional CPE details can be found here.Join us Tuesday, February 13th from 7-9pm for our next live course:From A1C to Z: A Sweet Update on Diabetes GuidelinesThis course will review the latest revisions to the American Diabetes Association (ADA) Standards of Care specifically highlighting the rising rates of obesity-related to diabetes, a pressing health concern affecting millions worldwide and often referred to as "diabesity". Learners will gain insights into nuances related to medication management and therapeutic decision-making for patients with diabetes. Content will provide guidance for reviewing and crafting patient-centered treatment strategies that holistically address glucose management while fostering improvements in cardio-metabolic, kidney, liver, and cognitive health for individuals grappling with diabetes and related comorbidities. Follow CEimpact on Social Media:LinkedInInstagram

Insulin icodec is the first class of long-acting insulin to be administered only once a week. Join host, Jen Moulton, as she discusses the safety and efficacy of insulin icodec with guest, Geoff Wall.The GameChangerInsulin icodec is the first of the ultra long-acting insulins with once weekly dosing. Multiple clinical studies have suggested these pharmacokinetics work. A new meta-analysis suggests that insulin icodec is more effective than other basal insulins and at least as safe concerning hypoglycemia.Jen Moulton, RPhPresident + FounderCEimpactGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceWang P, Zhang Y, Xu W, et al. Efficacy and Safety of Once-Weekly Insulin Regimes on Glycemic Control for Type 2 Diabetes: A Systematic Review and Network Meta-analysis. Diabetol Metab Syndr. 2024 Jan 3;16(1):3. doi: 10.1186/s13098-023-01240-5. PMID: 38172995; PMCID: PMC10763463.https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-023-01240-5#Sec19 Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Explain the chemical and structural changes that make icodec different from other basal insulins 2. Discuss the results of the meta-analysis about insulin icodec0.05 CEU/0.5 HrUAN: 0107-0000-24-043-H01-PInitial release date: 1/29/2024Expiration date: 1/29/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Alcohol Use Disorder (AUD) and cirrhosis are common medical conditions with significant morbidity and mortality. Join host, Geoff Wall, as he evaluates the new  American College of Gastroenterology guidelines.  The GameChangerThe MELD score is now preferred over the Madrey score for assessing mortality. Baclofen is the primary treatment for reducing consumption and craving in alcohol use disorder. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceJophlin LL, Singal AK, Bataller R, Wong RJ, Sauer BG, Terrault NA, Shah VH. ACG Clinical Guideline: Alcohol-Associated Liver Disease. Am J Gastroenterol. 2024 Jan 1;119(1):30-54. doi: 10.14309/ajg.0000000000002572. Epub 2023 Sep 1. PMID: 38174913.https://journals.lww.com/ajg/fulltext/2024/01000/acg_clinical_guideline__alcohol_associated_liver.13.aspx?context=featuredarticles&collectionid=5 Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the initial treatment of a patient admitted with acute alcoholic hepatitis2. Describe a pharmacotherapeutic plan for adjunctive treatment of alcohol use disorder0.05 CEU/0.5 HrUAN: 0107-0000-24-042-H01-P Initial release date: 1/22/2024Expiration date: 1/22/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Communication is ‘an essential duty’ of a pharmacist and the cornerstone of quality patient care. And yet, it continues to be one of the most common frustrations reported by preceptors when working with students and residents. Many factors may be at play, including a pandemic, as well as a digital society where so much communication happens in quick, abbreviated bytes.On this episode, guest Christine Klein reminds us of the many facets of communication, the complex range of reasons some students and residents may struggle, and how we as mentors and teachers can support their development in this area effectively.HostKathy Schott, PhDVice President, Education & OperationsCEimpactGuestDr. Christine Klein, PharmDVice-Chair for Experiential EducationClinical Associate ProfessorMercer University College of PharmacyGet CE: CLICK HERE TO CPE CREDIT FOR THE COURSE!CPE Information Learning ObjectivesAt the end of this course, preceptors will be able to:1. Discuss the importance of strong communication skills for students and residents 2. Describe the preceptor's role in fostering professional communication 0.05 CEU/0.5 HrUAN: 0107-0000-24-041-H99-P Initial release date: 1/17/2024Expiration date: 1/17/2025Additional CPE details can be found here.The speakers have no relevant financial relationships with ineligible companies to disclose.This program has been:Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors.Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors.Follow CEimpact on Social Media:LinkedInInstagram

Hyponatremia is a side effect of most diuretics but the incidence from thiazides is unknown. Join host, Geoff Wall, as he evaluates a new study from Denmark evaluating hyponatremia and thiazides. The GameChangerThiazide diuretics are considered first-line therapy but electrolyte side effects are underevaluated. A new study suggests hyponatremia is significantly more common than previously reported, especially in the elderly. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceAndersson NW, Wohlfahrt J, Feenstra B, et al. Cumulative Incidence of Thiazide-Induced Hyponatremia: A Population-Based Cohort Study. Ann Intern Med. 2023 Dec 19. doi: 10.7326/M23-1989. Epub ahead of print. PMID: 38109740.https://www.acpjournals.org/doi/abs/10.7326/M23-1989?journalCode=aim Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the use of thiazides in hypertension and their adverse effects 2. Assess the strengths and weaknesses of the Andersson et al study0.05 CEU/0.5 HrUAN: 0107-0000-24-032-H01-PInitial release date: 1/15/2024Expiration date: 1/15/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Sickle cell disease (SCD) is a devastating medical condition causing pain, fatigue, and early mortality. Join host, Geoff Wall, as he evaluates a new gene therapy via CRISPR that may cure SCD. The GameChangerCRISPR is a new method to develop targeted gene editing treatments. Lovo-cel is the first FDA-approved therapy and may treat sickle cell disease (SCD) - for only $2 million. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint Health ReferenceFDA Approval. https://www.fda.gov/vaccines-blood-biologics/lyfgenia. Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss what CRISPR is and how it can be used to treat diseases 2. Describe the use of lovotibeglogene autotemcel (lovo-cel) for sickle cell disease and its safety and efficacy data 0.05 CEU/0.5 HrUAN: 0107-0000-24-031-H01-PInitial release date: 1/8/2024Expiration date: 1/8/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram

Atrial fibrillation is the most common clinical arrhythmia. The newest guidelines have significant changes in diagnosis, assessment, and treatment. Join host, Geoff Wall, with guest Matt Boyd, as they evaluate the pharmacotherapy changes in the new guidelines in this two-part episode.The GameChangerRate and rhythm control medications largely have the same clinical outcomes. Patients with heart failure with reduced ejection fraction should try rhythm control first. Monitoring is key for atrial fibrillation pharmacotherapy. HostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthGuest Mathew Boyd, PharmD Clinical PharmacistUnity PointReferenceJoglar JA, Chung MK, Armbruster AL, et al. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2023 Nov 23:S0735-1097(23)06465-3. doi: 10.1016/j.jacc.2023.08.017. Epub ahead of print. PMID: 38043043.https://www.jacc.org/doi/10.1016/j.jacc.2023.08.017Pharmacist Members, REDEEM YOUR CPE HERE! Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)CPE Information Learning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss rate versus rhythm control in patients with atrial fibrillation 2. Develop a monitoring plan and selection of medications in rhythm control0.05 CEU/0.5 HrUAN: 0107-0000-24-030-H01-PInitial release date: 1/5/2024Expiration date: 1/5/2025Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagram