Septic shock has a 40% mortality rate in many patients. Methylene blue has been shown in small non-controlled case series to have a benefit. Join host, Geoff Wall, as he reviews a randomized controlled study from Mexico on this novel strategy. The GameChangerMethylene blue is a specific inhibitor of the inducible nitric oxide synthase for indirect pressor effects. Despite confounders, this small study may be a good start for a larger randomized controlled study for methylene blue as early adjunct care in patients with septic shock.  Host Geoff Wall, PharmD, BCPS, FCCP, BCGP Professor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint Health  References and Resources  Ibarra-Estrada M, Kattan E, Aguilera-González P, et al. Early adjunctive methylene blue in patients with septic shock: a randomized controlled trial. Crit Care. 2023 Mar 13;27(1):110. doi: 10.1186/s13054-023-04397-7. PMID: 36915146; PMCID: PMC10010212.  Redeem your CPE here CPE (Pharmacist) https://learn.ceimpact.com/library/course/5768  Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membership https://www.ceimpact.com/  CE Information  Learning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Describe the potential physiologic mechanism of benefit for methylene blue in septic shock 2. Discuss the Ibarra-Estrada et al study limitations  0.05 CEU/0.5 Hr UAN: 0107-0000-23-XXX-H01-P Initial release date: XX/XX/2023 Expiration date: XX/XX/2024 Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

OTC Birth ControlThe proverbial ‘pill’ or hormonal contraception may be available over-the-counter (or at least a progestin-only version) by year’s end. Join guest host, Jake Galdo, as he discusses improved access to care with Erin Raney as the FDA debates over-the-counter status for hormonal contraceptives. The GameChangerWomen’s health is a priority area from a public health perspective – the US has lots of room for improvement. One initiative is to allow a progestin-only hormonal contraceptive have over-the-counter status; in other words, be available without prescription. Progestin-only therapy has unique counseling considerations, so pharmacy intervention can help to optimize care. HostJake Galdo, PharmD, MBA, BCPS, BCGPCourse Content and Developer, CEimpactManaging Network Facilitator, CPESN Health EquityCEO, Seguridad GuestErin C. Raney, Pharm.D., BCPS, BC-ADMProfessor of Pharmacy PracticeMidwestern University College of Pharmacy-Glendale References and Resources Opill Rx-to-OTC Switch Program. www.fda.gov/media/167893/download Redeem your CPE hereCPE (Pharmacist) https://learn.ceimpact.com/library/course/5768 Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membership https://www.ceimpact.com/  CE Information Learning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Discuss the efficacy of OTC hormonal contraceptive 2. Identify contraindications for OTC hormonal contraceptives  0.05 CEU/0.5 Hr UAN: 0107-0000-23-XXX-H01-P Initial release date: XX/XX/2023 Expiration date: XX/XX/2024 AdditionalCPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Sexually transmitted infection (STI) risk in high risk patients is a common problem compounded by antimicrobial resistance. Join host, Geoff Wall, with guest Amanda Bushman, as they discuss a new post-exposure prophylaxis (PEP) therapy for STI prevention  The GameChanger Sexually transmitted infection incidence is higher than most clinicians suspect. Doxycycline may offer effective post-exposure prophylaxis for some HIV positive patients.   Show Segments [insert here]  Host Geoff Wall, PharmD, BCPS, FCCP, BCGP Professor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint Health  Guest Amanda Bushman, PharmD, BCIDP Clinical Pharmacist, UnityPoint Health  References and Resources  Luetkemeyer AF, Donnell D, Dombrowski JC, et al. Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections. N Engl J Med. 2023 Apr 6;388(14):1296-1306. doi: 10.1056/NEJMoa2211934. PMID: 37018493; PMCID: PMC10140182.  Redeem your CPE here CPE (Pharmacist) https://learn.ceimpact.com/library/course/5768  Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membership https://www.ceimpact.com/  CE Information  Learning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Discuss the DOXY-PEP study 2. Apply results of DOXY-PEP to patient care  0.05 CEU/0.5 Hr UAN: 0107-0000-23-XXX-H01-P Initial release date: XX/XX/2023 Expiration date: XX/XX/2024 Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

While we all know students who may exhibit more confidence that they have the right to based on their actual knowledge and experience, more often as preceptors we have students who demonstrate a lack of confidence that gets in the way of their learning. It is easy to make assumptions about why a student demonstrates a lack of confidence, but often we have missed the mark. By understanding the root cause of waning confidence in a pharmacy learner, we can develop strategies to increase confidence and allow them to optimize their learning.  Dr. Kate Newman, Director of Experiential Education, and Dr. Stephanie Hunziker, Director of Skills and Simulation and a Clinical Assistant Professor are both from Southern Illinois University Edwardsville School of Pharmacy. They have recognized the negative impact that low confidence can have on learner outcomes and have lots to share about challenges and strategies for identifying the root cause of low confidence, as well as teaching tactics and methods to overcome them.  Host Kathy Schott, PhD CEimpact Guests Kate Newman, PharmD Director of Experiential Education Clinical Associate Professor, Pharmacy Practice Southern Illinois University Edwardsville, School of Pharmacy  Stephanie Hunziker, PharmD Director of Skills and Simulation Clinical Assistant Professor Southern Illinois University Edwardsville School of Pharmacy  Get CE Click here to access the course: https://learn.ceimpact.com/library/course/5678  CE Information At the end of this course, preceptors will be able to: 1. Recognize potential reasons as learner may appear to lack confidence in a clinical setting. 2. Discuss strategies to help students overcome barriers and increase confidence.  UAN: 0107-0000-23-208-H99-P Release Date: 05/17/2023 Expiration Date: 05/17/2026 The speakers have no relevant financial relationships with ineligible companies to disclose.  This program has been: Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors. Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors.  Want more information on this and related topics?   True Grit: Developing a Philosophy of Failure https://learn.ceimpact.com/library/course/3911 Pharmacy learners are innately afraid to look silly, say the wrong thing, or make mistakes that could result in negative feedback. This fear can manifest in a perceived lack of confidence. This course provides pearls for creating an safe and supportive environment where failure isn’t something to be ashamed of, but rather a path to greater learning.  We’ve also got a great podcast on this topic. Check out Season 2, Episode 1.  https://ceimpactpodcast.buzzsprout.com/1788250/9915405-developing-a-philosophy-of-failure  Using Feedback to Improve Your Teaching https://learn.ceimpact.com/library/group/36/course/5102  Feedback is essential to developing a trusting aFollow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

About 50% of Americans have hypertension, yet WHICH is a preferred anti-hypertensive strategy is a random process. And pharmacogenomics may not be needed. Join host, Geoff Wall, as he evaluates a recent study evaluating the role of personalized medication selection for persons with hypertension.  The GameChanger Although no genetic markers exist to determine optimal hypertensive pharmacotherapy, initial and secondary hypertensive therapy does impact outcomes. A personalized approach does produce a greater reduction in blood pressure.   Show Segments [insert here]  Host Geoff Wall, PharmD, BCPS, FCCP, BCGP Professor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint Health  References and Resources  Sundström J, Lind L, Nowrouzi S, et al. Heterogeneity in Blood Pressure Response to 4 Antihypertensive Drugs: A Randomized Clinical Trial. JAMA. 2023;329(14):1160–1169. doi:10.1001/jama.2023.3322  Redeem your CPE here CPE (Pharmacist) https://learn.ceimpact.com/library/course/5768  Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membership https://www.ceimpact.com/  CE Information  Learning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Describe the results of the PHYSIC study 2. Discuss the limitations of the PHYSIC study  0.05 CEU/0.5 Hr UAN: 0107-0000-23-XXX-H01-P Initial release date: XX/XX/2023 Expiration date: XX/XX/2024 Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Respiratory syncytial virus (RSV) is a leading cause of pneumonia and hospitalizations in children and older adults. A search for a vaccine may finally be over. Join host, Geoff Wall, and guest, Jake Galdo, as they dive into part 2 of a two-part series examining new research on the proposed RSV vaccine.  The GameChanger RSV, COVID-19, and influenza are major disease burdens on children and older adults. Fortunately, COVID-19 and influenza have widely available vaccines – and maybe soon for RSV. A recent study of the mRNA vaccine in pregnant patients may help newborns.   Show Segments00:00 - Introductions02:57 - Recap From Part 106:45 - Looking at the MATISSE Study14:17 - The GameChanger: MATISSE Results22:27 - Connecting to Practice: Barriers to Applying 31:05 - Closing Remarks   Host Geoff Wall, PharmD, BCPS, FCCP, BCGP Professor of Pharmacy Practice, Drake University Internal Medicine/Critical Care, UnityPoint Health  Guest Jake Galdo, PharmD, MBA, BCPS, BCGP Managing Network Facilitator, CPESN Health Equity CEO, Seguridad  References and Resources  Kampmann B, Madhi SA, Munjal I, et al. Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants. N Engl J Med. 2023 Apr 20;388(16):1451-1464. doi: 10.1056/NEJMoa2216480. Epub 2023 Apr 5. PMID: 37018474.  Redeem your CPE here CPE (Pharmacist) https://learn.ceimpact.com/library/course/5769  Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode) Pharmacists: Get a membership  CE Information  Learning Objectives Upon successful completion of this knowledge-based activity, participants should be able to: 1. Discuss the MATISSE study in relation to RSV vaccines 2. Describe barriers to applying the information in this study to general populations  0.05 CEU/0.5 Hr UAN: 0107-0000-23-193-H06-P Initial release date: 05/08/2023 Expiration date: 05/08/2024 Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Respiratory syncytial virus (RSV) is a leading cause of pneumonia and hospitalizations in children and older adults. A search for a vaccine may finally be over. Join host, Geoff Wall, and guest, Jake Galdo, as they dive into part 1 of a two-part series examining new research on the proposed RSV vaccine.The GameChangerRSV, COVID-19, and influenza are major disease burdens on children and older adults. Fortunately, COVID-19 and influenza have widely available vaccines – and maybe soon for RSV. A recent study of the mRNA vaccine in older adults improves antibody titers. Show Segments 00:00 - Introductions03:06 - Barriers to Development of the RSV Vaccine06:46 - Looking at the RSV Vaccine Study13:01 - The GameChanger: The Vaccine Outcomes20:57 - Connecting to Practice: The Potential Future of This Vaccine28:19 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthGuestJake Galdo, PharmD, MBA, BCPS, BCGPManaging Network Facilitator, CPESN Health EquityCEO, SeguridadReferences and ResourcesFalsey AR, Hennessey PA, Formica MA, Cox C, Walsh EE. Respiratory syncytial virus infection in elderly and high-risk adults. N Engl J Med. 2005 Apr 28;352(17):1749-59. doi: 10.1056/NEJMoa043951. PMID: 15858184.Redeem your CPE hereCPE (Pharmacist) Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe barriers to development of an RSV vaccine2. Discuss outcomes of an RSV vaccines in older adults0.05 CEU/0.5 HrUAN: 0107-0000-23-192-H06-PInitial release date: 05/01/2023Expiration date: 05/01/2024Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Community Acquired Pneumonia (CAP) has a high mortality rate. A new study evaluates the use of hydrocortisone for severe CAP in the ICU setting. Join host, Geoff Wall, as he evaluates if the evidence stacks up.The GameChangerThe use of steroids to treat severe pneumonia has waxed and waned for many years with insufficient evidence. A recent study found steroids improved a number of outcomes, including mortality.Show Segments00:00 - Introductions01:19 - Past Studies on CAP Treatment03:32 - The CAPE Code Study17:05 - The GameChanger: The Study Findings24:31 - Connecting to Practice: Study Limitations26:01 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesHydrocortisone in Severe Community-Acquired PneumoniaRedeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe the past history of major mortality studies for CAP pharmacotherapy2. Discuss the CAPE Code study and its possible implications in the ICU0.05 CEU/0.5 HrUAN: 0107-0000-23-147-H01-PInitial release date: 04/24/2023Expiration date: 04/24/2024Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Co-precepting can help with workload while providing a diverse experience for learners, but it is not without its challenges. Listen in to weigh the pros and cons while gathering some strategies to ensure success if you plan to consider, or are currently, co-precepting with a colleague.Kate Newman is the Director of Experiential Education at Southern Illinois University Edwardsville School of Pharmacy. She’s been seeing more co-precepting arrangements with her affiliate experiential education sites and has seen what works, and of course what doesn’t work. I asked her to share some tips and strategies with me that have helped ensure a good learning experience at sites where preceptors are sharing the teaching load. Listen in!HostKathy Schott, PhDCEimpactGuestsKate Newman, PharmDDirector of Experiential EducationClinical Associate Professor, Pharmacy PracticeSouthern Illinois University Edwardsville, School of PharmacyGet CEClick here to access the courseCE InformationAt the end of this course, preceptors will be able to:1. Describe co-precepting and the pros and cons commonly associated with it.2. Identify potential challenges and strategies to address them.UAN: 0107-0000-23-149-H99-P Release Date: 04/19/2023 Expiration Date: 04/19/2026 The speakers have no relevant financial relationships with ineligible companies to disclose.This program has been:Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors.Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors. Want more information on this and related topics?  Using Feedback to Improve Your Teaching Feedback may be more important than ever when working in a co-precepting environment – from students and from your fellow co-preceptors. This course will give you some proven strategies for accepting and implementing critical feedback on your teaching.Tools to Facilitate Student Success with Your Learning Experience Preceptors often don’t feel they have time or know how to go about creating an appropriate amount of structure within the experiences they provide for student pharmacists. In this CPE course, preceptors have the opportunity to learn and apply simple quality improvement techniques to maintain and enhance their learning experience.The Eleven Habits of Highly Effective PreceptorsRegardless of your precepting environment, there’s always room for self-assessment. This tool will allow you to assess your own strengths and areas for development as a preceptor so that you can develop your own professional development plan as a teacher and mentor. As always, be sure to check out the full library of courses available for preceptors on the CEimpact website. Be sure to ask you experiential program director if you are a member so that you can access it all for free!Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Several studies have found the improved outcomes and quality of life through deprescribing. However, it rarely happens. Join host, Geoff Wall, with guest, Kristin Meyer, as they evaluate a new studying looking at pharmacist-provided describing services during transition of care.The GameChangerOlder patients are on numerous medications often with limited therapeutic benefit and high risk of adverse events. Many of these medications can be discontinued with no change in outcomes. Pharmacists are uniquely positioned to support deprescribing protocols. Show Segments00:00 - Introductions01:46 - Arguments for Deprescribing05:44 - Looking at the Study16:32 - The GameChanger: Deprescribing Results22:42 - Connecting to Practice: Dr. Meyer’s Thoughts on Results31:08 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, BCGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthGuestKristin Meyer, PharmD, BCGPProfessor of Pharmacy Practice, Drake UniversityReferences and ResourcesVasilevskis EE, Shah AS, Hollingsworth EK, et al. Deprescribing Medications Among Older Adults From End of Hospitalization Through Postacute Care: A Shed-MEDS Randomized Clinical Trial. JAMA Intern Med. 2023;183(3):223–231. doi:10.1001/jamainternmed.2022.6545O'Mahony D. STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: origin and progress. Expert Rev Clin Pharmacol. 2020 Jan;13(1):15-22. doi: 10.1080/17512433.2020.1697676. Epub 2019 Nov 30. PMID: 31790317.Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the importance and benefits of deprescribing medications in elderly patients2. Discuss the assessment scoring systems used to assess deprescribing activities0.05 CEU/0.5 HrUAN: 0107-0000-23-146-H01-PInitial release date: 04/17/2023Expiration date: 04/17/2024Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

ICU patients are at high risk for venous thromboembolism, and the majority of patients require prophylaxis. The challenging therapy is thrombocytopenia. Join host Geoff Wall, as he evaluates the results of a new study evaluating the clinical thresholds for chemical prophylaxis.The GameChangerThe majority of ICU patients eligible for VTE prophylaxis do not receive it. Different clinicians use different thresholds to initiate or stop prophylaxis. The database study discussed provides a potential evidence-based threshold.Show Segments00:00 - Introductions00:47 - VTE Prophylaxis Background09:34 - Looking at the Study18:42 - The GameChanger: A Potential Threshold for Chemical Prophylaxis22:15 - Connecting to Practice: Applicability26:13 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesAssociation between Early Venous Thromboembolism Prophylaxis, Bleeding Risk, and Venous Thromboembolism among Critically Ill Patients with Thrombocytopenia. Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the history and use of VTE prophylaxis in the ICU2. Describe the results of the Pang et al study discussed and its applicability to ICU patients0.05 CEU/0.5 HrUAN: 0107-0000-23-134-H01-PInitial release date: 04/10/2023Expiration date: 04/10/2024Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

The Updated AAAAI Guidelines on Drug AllergiesDrug allergies are a common challenge for all prescribers, patients, and pharmacies. They are associated with increased costs, adverse effects, and extended hospitalizations. Join host Geoff Wall as he reviews the newly released AAAI guidelines on drug allergies.The GameChangerOver 90% of patients claiming a penicillin allergy are not allergic. Sulfamethoxazole desensitization is largely not needed. A thorough evaluation of patient allergies with testing may help establish true allergies in patients and help optimize pharmacotherapy.Show Segments00:00 - Introductions01:55 - Changes in Classifications07:35 - The GameChanger: Beta-Lactam Allergy Approach21:05 - Sulfonamide Allergy Approach27:04 - Non-Steroidal Allergy Approach30:05 - Connecting to Practice: Applying these Changes30:58 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesA 2022 practice parameter update. Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss approaches to a patient with a claimed penicillin allergy who requires a beta lactam2. Discuss the protocol for desensitization for a sulfonamide allergic patient when a sulfonamide is required0.05 CEU/0.5 HrUAN: 0107-0000-23-133-H01-PInitial release date: 04/03/2023Expiration date: 04/03/2024Additional CPE details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Although the numbers may be low, COVID-19 and other illnesses remain a significant threat to patients. The role of masks in preventing SARS-CoV-2 spread has been politicized since the beginning. A new meta-analysis purports to answer the question of mask effectiveness. Join host Geoff Wall, with guest Jake Galdo, as they deep dive into the article and evaluate the science.The GameChangerA new meta-analysis suggests that mask mandates do not affect the prevention and spread of COVID-19. However, the study has numerous limitations and errors, making its interpretation difficult.Show Segments00:00 - Introductions01:31 - Pros and Cons of a Meta-Analysis06:31: Looking at the Analysis10:24 - The GameChanger: Jefferson et al. Results11:24 - Connecting to Practice: Recognizing Limitations28:43 - Closing Remarks HostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthJake Galdo, PharmD, MBA, BCPS, BCGPCourse Content and Developer, CEimpactManaging Network Facilitator, CPESN Health EquityCEO, SeguridadReferences and ResourcesJefferson T, Dooley L, Ferroni E, et al. Physical interventions to interrupt or reduce the spread of respiratory viruses (Review). Cochrane Library.  Novella S. Masks Revisited. Science Based Medicine. Redeem your CPE hereCPE (Pharmacist) Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the pros and cons of a meta-analysis2. Describe the limitations of the Jefferson et al meta-analysis0.05 CEU/0.5 HrUAN: 0107-0000-23-119-H01-PInitial release date: 03/22/2023Expiration date: 03/22/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Pharmacogenomics have long held the promise of using personalized information for drug selection to maximize efficacy and minimize adverse reactions. A new study evaluates the routine use of pharmacogenomic testing to improve safety in a wide range of medications. Join host, Geoff Wall, as he evaluates personalized medicine.The GameChangerMost studies using routine pharmacogenomic testing in clinical practice have not been significant. However, a new study found a 12 panel pharmacogenomic test did decrease the incidence of patient reported adverse effects compared to usual care. Several limitations still exist preventing widespread implementation.Show Segments00:00 - Introductions01:38 - Genomic Guided Therapy to Date05:05 - Importance of Genomic Variations08:37 - Looking at the Study21:20 - The GameChanger: Swen et al Results27:50 - Connecting to Practice: Current Barriers to Pharmacogenomic Testing30:38- Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesA 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study. Clinical Pharmacogenomics Implementation Consortium. Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Describe current barriers to routine use of pharmacogenomic testing2. Discuss issues and results of the Swen et al study on pharmacogenomics0.05 CEU/0.5 HrUAN: 0107-0000-23-118-H01-PInitial release date: 03/20/2023Expiration date: 03/20/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Pharmacy learners - IPPE, APPE, Residents - may not always be forthcoming with honest feedback. But they know what they appreciate (or don't) in a learning experience. As a preceptor, your approach to teaching has a huge impact on student learning.We asked two 4th year pharmacy learners to share what matters most to them in a preceptor. Their answers may surprise you! Listen in to learn what students most value in their learning experiences and gather some strategies you can use to enhance your teaching and mentor in an impactful way for your learners. HostKathy Schott, PhDCEimpact GuestsLily Gardner, PharmD Candidate 2023Drake UniversityKeaton Higgins, PharmD Candidate 2023University of Iowa Get CEClick here to access the courseCE InformationAt the end of this course, preceptors will be able to:1. Identify practices that pharmacy learners most value in their preceptors and why2. Describe effective strategies to enhance learning in the pharmacy education experience you provide UAN: 0107-0000-23-116-H99-P Release Date: 03/15/2023 Expiration Date: 03/15/2026 The speakers have no relevant financial relationships with ineligible companies to disclose. This program has been:Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors.Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors.Want more information on this and related topics? Check out the full course created by Dr. Cox on this topic: Using Feedback to Improve Your Precepting, and learn what you can do to help facilitate better feedback from your learners.This book is a great resource for building feedback skills – Thanks for the Feedback: The Science and Art of Receiving Feedback Well. I’ve read this book and there’s something in it for everyone – from a teacher, mentor, preceptor, parent, partner, or spouse. Check out the LINK! As always, be sure to check out the full library of courses available for preceptors on the CEimpact website. Be sure to ask you experiential program director if you are a member so that you can access it all for free! Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

For the past two decades, large amounts of isotonic fluids have been the first step in treating septic shock despite adverse events of fluid overload, coagulopathy, and pulmonary edema. A new NIH study evaluates this strategy. Join host, Geoff Wall, with guest, Matt Trump, DO, as they evaluate initial septic shock management.The GameChangerLiberal fluid management (30 mL/Kg) in the early phase of septic shock may not result in lower mortality than a more restrictive strategy. However, vasopressor predominant strategy may be used in its place.Show Segments00:00 - Introductions01:08 - Background on Fluid Administration in Septic Shock05:44 - Looking at the Study15:55 - The GameChanger: Shapiro et al Results21:21 - Connecting to Practice: What Should We Takeaway34:31 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthMatt Trump, DOIowa ClinicsReferences and ResourcesEarly Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension.Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the background of fluid administration in septic shock2. Describe the results of the Shapiro et al study0.05 CEU/0.5 HrUAN: 0107-0000-23-103-H01-PInitial release date: 03/13/2023Expiration date: 03/13/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Every January, the American Diabetes Association publishes the Standards of Care in Diabetes. The guidelines are a living document and change throughout the year; however, the January update is the seminal changes for the entire document. Join host, Geoff Wall, with guest, Jake Galdo, as they discuss what’s new and great in the guidelines.The GameChangerIn addition to medication recommendations, the guidelines now emphasize the role of Community Health Workers in the management of health-related disparities affecting patients with diabetes. Pharmacotherapy continues to be driven by comorbid conditions and the impact of clinical outcomes, like a cardiovascular or renal disease.Show Segments00:00 - Introductions01:59 - Prevention and Delay of Type 2 Diabetes08:12 - Vaccines and Diabetes10:49 - Continuous Glucose Monitoring Goals17:21 - Glycemic Treatment Updates19:25 - Lipid Goals and Treatment20:39 - The GameChanger: Treatment Recommendations with Comorbid Conditions23:49 - Connecting to Practice: Comorbid Driven Therapy27:31 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthJake Galdo, PharmD, MBA, BCPS, BCGPCourse Content and Developer, CEimpactManaging Network Facilitator, CPESN Health EquityCEO, SeguridadReferences and ResourcesAmerican Diabetes Association. Standards of Care in Diabetes-2023 Abridged for Primary Care Providers. Redeem your CPE hereCPE (Pharmacist) Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the goal for continuous glucose monitoring in diabetes patients2. Describe the lipid goals in patients with diabetes and treatment recommendations3. Describe treatment recommendations for patients with diabetes and chronic kidney disease0.05 CEU/0.5 HrUAN: 0107-0000-23-102-H01-PInitial release date: 03/06/2023Expiration date: 03/06/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Furosemide is the most prescribed loop diuretic for heart failure; however, furosemide’s pharmacokinetic parameters are less than ideal compared to other loop diuretics. Join host, Geoff Wall, as he evaluates the first randomized controlled trial comparing loop diuretics in heart failure.The GameChangerTorsemide has potential pharmacokinetic advantages compared to furosemide in the treatment of heart failure. However, a recent study did not find meaningful differences in clinical outcomes when comparing loop diuretics for the treatment of heart failure.Show Segments00:00 - Introduction01:00 - Current Loop Diuretic Use02:21 - Furosemide vs Torsemide Pharmacokinetics04:58 - Looking at the TRANSFORM-HF Study14:54 - The GameChanger: TRANSFORM-HF Outcomes19:16 - Connecting to Practice: Picking Between the Two21:52 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthReferences and ResourcesEffect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart Failure: The TRANSFORM-HF Randomized Clinical Trial. Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. List the pharmacokinetic differences between furosemide and torsemide2. Discuss the findings of the Mentz et al study evaluating loop diuretics0.05 CEU/0.5 HrUAN: 0107-0000-23-101-H01-PInitial release date: 02/27/2023Expiration date: 02/27/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

Routine pediatric vaccines are declining and 97% of pediatric influenza deaths are in unvaccinated children. Join host Geoff Wall, with guest Jake Galdo, as they discuss what the heck is happening with pediatric vaccines and how the healthcare community can step up.The GameChangerThe Advisory Committee on Immunization Practices provides recommendations for routine vaccines for all persons. Pharmacists are an integral part of ensuring adherence to vaccine schedules. Differences in state scope of practice may influence what vaccines may be administered, but not what vaccines can be recommended.Show Segments00:00 - Introductions00:53 - Pediatric Vaccine Coverage02:51 - Connecting to Practice: How Pharmacists Can Help14:21 - The GameChanger: Pediatric COVID Vaccines26:22 - Closing RemarksHostGeoff Wall, PharmD, BCPS, FCCP, CGPProfessor of Pharmacy Practice, Drake UniversityInternal Medicine/Critical Care, UnityPoint HealthJake Galdo, PharmD, MBA, BCPS, BCGPCourse Content and Developer, CEimpactManaging Network Facilitator, CPESN Health EquityCEO, SeguridadReferences and ResourcesVaccination Coverage with Selected Vaccines and Exemption Rates Among Children in Kindergarten - United States, 2021-22 School Year. Redeem your CPE hereCPE (Pharmacist)Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)Pharmacists: Get a membershipCE InformationLearning ObjectivesUpon successful completion of this knowledge-based activity, participants should be able to:1. Discuss the current state of pediatric vaccinations in the US2. Describe clinical information to be collected during pediatric vaccinations0.05 CEU/0.5 HrUAN: 0107-0000-23-100-H01-PInitial release date: 02/20/2023Expiration date: 02/20/2024Additional CPE and CME details can be found here.Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!

As preceptors, sometimes one of the hardest things we do is give feedback. What about when we receive it? Listen to learn how to engage students in ways that result in meaningful feedback you can use to improve your teaching. You're putting in the work. Why not make it as impactful as possible for your learners?This week I’m speaking with Nick Cox – a faculty member and preceptor in an ambulatory care setting – on the topic of feedback – how to invite it, how to prepare to receive it, and what to do with it when you like it – or not.  As part of our discussion, Nick refers to this book – Thanks for the Feedback: The Science and Art of Receiving Feedback Well. I’ve read this book, and there’s something in it for everyone – from a teacher, mentor, preceptor, parent, partner, or spouse. Check out the Here!HostKathy Schott, PhDCEimpact GuestNicholas Cox, PharmD BCACPAssistant Professor (Clinical)University of UtahGet CEClick here to access the courseCE InformationAt the end of this course, preceptors will be able to:1. List common barriers that prevent learners from providing meaningful feedback to preceptors.2. Describe ways to create a learning environment where students feel they can safely offer feedback.UAN: 0107-0000-23-092-H99-PRelease Date: 02/15/2023Expiration Date: 02/15/2026The speakers have no relevant financial relationships with ineligible companies to disclose.This program has been:Approved by the Minnesota Board of Pharmacy as education for Minnesota pharmacy preceptors.Reviewed by the Texas Consortium on Experiential Programs and has been designated as preceptor education and training for Texas preceptors. Want more information on this and related topics? Check out the full course created by Dr. Cox on this topic: Using Feedback to Improve Your Precepting, and learn what you can do to help facilitate better feedback from your learners. As always, be sure to check out the full library of courses available for preceptors on the CEimpact website. Be sure to ask your experiential program director if you are a member so that you can access it all for free!  Follow CEimpact on Social Media:LinkedInInstagramDownload the CEimpact App for Free Continuing Education + so much more!