Global Child and Adolescent Health

Melbourne Children’s Global Health

The Global Child and Adolescent Health podcast is brought to you by Melbourne Children’s Global Health. The podcast is a series of conversations with leaders in research, education, and global child and adolescent health. These conversations place children and adolescents at the center of sustainable development. read less
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Episodes

A career in treating and preventing HIV in children and adolescents
Sep 11 2023
A career in treating and preventing HIV in children and adolescents
In this episode Professor Steve Graham talks to Professor Mark Cotton, Department of Paediatrics and Child Health, Stellenbosch University. They discuss his early medical career, as the first paediatric infectious disease specialist in South Africa and one of the first doctors in Africa to treat children with antiretrovirals (ARVs), leading the Children with HIV Early Antiretroviral Therapy (CHER) trial, and current involvement in TB and HIV vaccine trials at Family Centre for Research with Ubuntu (FAMCRU). -- Professor Mark Cotton’s research has focussed on HIV and TB in children. Prof Cotton obtained his undergraduate degree in Medicine from the University of Cape Town; Master’s from the University of the Witwatersrand; and PhD in Immunology from Stellenbosch University. He interned at Groote Schuur Hospital and completed his postgraduate paediatrics training at various South African health facilities. After a Fellowship in Paediatric Infectious Diseases at the University of Colorado, he returned to South Africa to establish the Children’s Infectious Diseases Clinical Research Unit (KIDCRU). He is an Emeritus Professor at Stellenbosch University and advises World Health Organization on HIV in children. He has published/co-published more than 390 peer-reviewed articles in journals such as Lancet and the New England Journal of Medicine. He served on various editorial boards and was president of the World Society of Paediatric Infectious Diseases between 2019 and 2022. He now chairs its Education Committee.
Bridging the knowledge-practice gap in tuberculosis management in Indonesia and Mongolia
Aug 15 2023
Bridging the knowledge-practice gap in tuberculosis management in Indonesia and Mongolia
In this episode Professor Steve Graham discusses bridging the knowledge-practice gap in tuberculosis management with Dr Trisasi Lestari, Universitas Gadjah Mada, Indonesia, and Dr Bazarragchaa Tsogt, Mongolian Anti-Tuberculosis Coalition, Mongolia. Dr Trisasi Lestari is a tuberculosis (TB) researcher at the Center for Tropical Medicine at the University of Gadjah Mada, Indonesia. Dr Lestari is also a PhD candidate at Menzies School of Health Research at Charles Darwin University. Dr Bazarragchaa Tsogt, Mongolian Anti-Tuberculosis Coalition. Professor Steve Graham is a Co-Chair for Melbourne Children's Global Health, Professor of International Child Health, University of Melbourne and Group Leader, International Child Health, Murdoch Children's Research Institute.   Further reading: du Preez K, Gabardo BMA, Kabra SK, Triasih R, Lestari T, Kal M, Tsogt B, Dorj G, Purev E, Nguyen TA, et al. Priority Activities in Child and Adolescent Tuberculosis to Close the Policy-Practice Gap in Low- and Middle-Income Countries. Pathogens. 2022; 11(2):196. https://doi.org/10.3390/pathogens11020196Lestari T, Kamaludin, Lowbridge C, Kenangalem E, Poespoprodjo JR, Graham SM, Ralph AP. Impacts of tuberculosis services strengthening and the COVID-19 pandemic on case detection and treatment outcomes in Mimika District, Papua, Indonesia: 2014-2021. PLOS Glob Public Health. 2022 Sep 30;2(9):e0001114. doi: 10.1371/journal.pgph.0001114. PMID: 36962674; PMCID: PMC10021881.Main S, Lestari T, Triasih R, Chan G, Davidson L, Majumdar S, Santoso D, Phung S, Laukkala J, Graham S, du Cros P, Ralph A. Training for Tuberculosis Elimination in Indonesia: Achievements, Reflections, and Potential for Impact. Trop Med Infect Dis. 2019 Jul 18;4(3):107. doi: 10.3390/tropicalmed4030107. PMID: 31323840; PMCID: PMC6789479.Lestari T, Graham S, van den Boogard C, Triasih R, Poespoprodjo JR, Ubra RR, Kenangalem E, Mahendradhata Y, Anstey NM, Bailie RS, Ralph AP. Bridging the knowledge-practice gap in tuberculosis contact management in a high-burden setting: a mixed-methods protocol for a multicenter health system strengthening study. Implement Sci. 2019 Mar 19;14(1):31. doi: 10.1186/s13012-019-0870-x. PMID: 30890160; PMCID: PMC6425655. South A, Dhesi P, Tweed CD, Tsogt B, Staples S, Tukvadze N, Dorj G, Zaca S, Sanikidze E, Purev N, Esmail H, Burgess R. Patients' priorities around drug-resistant tuberculosis treatment: A multi-national qualitative study from Mongolia, South Africa and Georgia. Glob Public Health. 2023 Jan;18(1):2234450. doi: 10.1080/17441692.2023.2234450. PMID: 37431789. Nunn AJ, Phillips PPJ, Meredith SK, Chiang CY, Conradie F, Dalai D, van Deun A, Dat PT, Lan N, Master I, Mebrahtu T, Meressa D, Moodliar R, Ngubane N, Sanders K, Squire SB, Torrea G, Tsogt B, Rusen ID; STREAM Study Collaborators. A Trial of a Shorter Regimen for Rifampin-Resistant Tuberculosis. N Engl J Med. 2019 Mar 28;380(13):1201-1213. doi: 10.1056/NEJMoa1811867. Epub 2019 Mar 13. PMID: 30865791.Goodall RL, Meredith SK, Nunn AJ, Bayissa A, Bhatnagar AK, Bronson G, Chiang CY, Conradie F, Gurumurthy M, Kirenga B, Kiria N, Meressa D, Moodliar R, Narendran G, Ngubane N, Rassool M, Sanders K, Solanki R, Squire SB, Torrea G, Tsogt B, Tudor E, Van Deun A, Rusen ID; STREAM study collaborators. Evaluation of two short standardised regimens for the treatment of rifampicin-resistant tuberculosis (STREAM stage 2): an open-label, multicentre, randomised, non-inferiority trial. Lancet. 2022 Nov 26;400(10366):1858-1868. doi: 10.1016/S0140-6736(22)02078-5. Epub 2022 Nov 8. Erratum in: Lancet. 2022 Nov 19;400(10365):1766. PMID: 36368336; PMCID: PMC7614824.