Decoding Healthcare Research

Agora Project

Welcome to "Decoding Healthcare Research", a podcast by Agora Project. Join us as we delve into the behind-the-scenes world of groundbreaking research and the dynamic healthcare industry, interviewing top paper authors, engaging experts on industry-related topics, and exploring medical subjects that affect our daily lives. read less
Health & FitnessHealth & Fitness

Episodes

Preventing ALZHEIMER'S: The Impact of High FRUCTOSE in our Brain Metabolism ft Dr. Perlmutter |Ep.33
5d ago
Preventing ALZHEIMER'S: The Impact of High FRUCTOSE in our Brain Metabolism ft Dr. Perlmutter |Ep.33
Join us in this enlightening episode as we explore the crucial connection between metabolic health and the preservation of brain function, with a special focus on preventing Alzheimer's disease and dementia. We'll delve into the pivotal roles of fructose and uric acid in this intricate relationship, shedding light on their detrimental effects when present in excessive amounts. We're thrilled to welcome esteemed guest Dr. David Perlmutter, a board-certified neurologist, Associate Professor at the Miami Miller School of Medicine, Fellow of the American College of Nutrition, and six-time New York Times best-selling author. Dr. Perlmutter brings his wealth of expertise to our conversation, offering invaluable insights into the intersection of metabolism and brain health. Our discussion transcends dietary considerations, exploring the profound impact of the modern American diet and the pivotal role of daily lifestyle choices in shaping cognitive outcomes. Discover how proactive measures taken as early as 30 years before symptoms manifest can significantly influence long-term brain health. Follow me on social media: Instagram: @doctoref.rain Facebook: Efrain Riveros-perez This conversation was based in the following article: Reference: Johnson RJ, Tolan DR, Bredesen D, Nagel M, Sánchez-Lozada LG, Fini M, Burtis S, Lanaspa MA, Perlmutter D. Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism? Am J Clin Nutr. 2023 Mar;117(3):455-466. doi: 10.1016/j.ajcnut.2023.01.002. Epub 2023 Jan 11. PMID: 36774227; PMCID: PMC10196606. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Lower your CHOLESTEROL and INSULIN: Clarifying Misconceptions About Dietary CHOLESTEROL |Ep.32
May 8 2024
Lower your CHOLESTEROL and INSULIN: Clarifying Misconceptions About Dietary CHOLESTEROL |Ep.32
In this episode, we dive deep into the realm of cholesterol, unveiling its connection to metabolism and the crucial role of insulin in its regulation. We tackle questions such as:Is dietary cholesterol associated with cardiovascular risk and cardiovascular disease? Can I lower my cholesterol and still eat cholesterol? Is dietary cholesterol healthy? What food has the most cholesterol in it? Discover how our dietary habits impact our metabolic health and influence cholesterol levels. Join us as we explore the intricate interplay between nutrition, metabolism, and overall well-being. Follow me on social media: Instagram: https://www.instagram.com/doctoref.rain/ Facebook: https://www.facebook.com/efrain.riverosperez Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Does FASTING hold the secret to extending lifespan? |Ep.31
May 1 2024
Does FASTING hold the secret to extending lifespan? |Ep.31
Join us in this episode as we delve into the intriguing topic of fasting and the fasting mimicking diet, and their profound impact on healthy lifespan. Our esteemed guest, Dr. Valter Longo, PhD in biochemistry and the Edna M. Jones Professor of Gerontology and Biological Sciences at the University of Southern California – Leonard Davis School of Gerontology, Los Angeles, shares invaluable insights from his extensive research at one of the foremost centers for aging and age-related disease studies. Dr. Longo, also serving as the Director of the Longevity and Cancer Program at the IFOM Institute of Molecular Oncology in Milan, Italy, brings a wealth of knowledge to the table. Through this engaging discussion, we explore the mechanisms behind fasting's effects on longevity, the science of the fasting mimicking diet, and its potential implications for human health and disease prevention. This conversation was based on the following article: Reference: Longo VD, Panda S. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan. Cell Metab. 2016 Jun 14;23(6):1048-1059. doi: 10.1016/j.cmet.2016.06.001. PMID: 27304506; PMCID: PMC5388543. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Vitamin D and Insulin Resistance: What's the connection? |Ep.30
Apr 24 2024
Vitamin D and Insulin Resistance: What's the connection? |Ep.30
In this episode, Dr. Alan Sacerdote MD, an endocrinologist specializing in diabetes and metabolism, discusses the crucial role of Vitamin D in metabolic health. Discover how Vitamin D deficiency correlates with various metabolic conditions and learn practical strategies for supplementation and lifestyle adjustments. Tune in for expert insights into optimizing metabolic health with Vitamin D. Dr. Sacerdote occupied the position of Chief of the Endocrinology Division at NYC Health and Hospitals Woodhull, and served as a Professor at SUNY Downstate Medical Center and New York University School of Medicine, among others. This conversation was based on the following article: Reference: Sacerdote A, Dave P, Lokshin V, Bahtiyar G. Type 2 Diabetes Mellitus, Insulin Resistance, and Vitamin D. Curr Diab Rep. 2019 Sep 10;19(10):101. doi: 10.1007/s11892-019-1201-y. PMID: 31506836. Don't forget to subscribe and follow me on social media. You can find me on Instagram as @doctoref.rain and Facebook as Efrain Riveros-pérez. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Diet Strategies to Relieve Menopause Symptoms with Dr. Neal Barnard. |Ep. 29
Apr 17 2024
Diet Strategies to Relieve Menopause Symptoms with Dr. Neal Barnard. |Ep. 29
Discover how diet can be a game-changer in managing menopause symptoms like hot flashes in this special episode featuring Dr. Neal Barnard, MD, FACC. Join us as we delve into the transformative potential of a plant-based, specifically vegan, rich in soy in relieving or even eliminating hot flashes and other menopause symptoms. Dr. Barnard, an acclaimed Adjunct Professor of Medicine at George Washington University, , President of the Physicians Committee for Responsible Medicine, and a New York Times bestselling author of 20 books, shares evidence-based insights into how dietary interventions can empower women to navigate menopause with ease and vitality. Don't forget to subscribe and follow me on social media. You can find me on Instagram as @doctoref.rain and Facebook as Efrain Riveros-pérez. This episode was based on the following article: Reference: Barnard ND, Kahleova H, Holtz DN, Znayenko-Miller T, Sutton M, Holubkov R, Zhao X, Galandi S, Setchell KDR. A dietary intervention for vasomotor symptoms of menopause: a randomized, controlled trial. Menopause. 2023 Jan 1;30(1):80-87. doi: 10.1097/GME.0000000000002080. Epub 2022 Oct 16. PMID: 36253903; PMCID: PMC9812421. Also available at: Spotify, Apple Podcasts and Amazon Music as Decoding Healthcare Research Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Exercise's transformative effects on adipose tissue. |Ep. 28
Apr 10 2024
Exercise's transformative effects on adipose tissue. |Ep. 28
In this episode, we will discuss the benefits of exercise, focusing specifically on its effects on adipose tissue and muscle. We will delve into the role that certain adipokines play, including thermogenesis and the browning of adipose tissue, which can represent significant positive changes for metabolism, health, and overall wellness. Joining us in this conversation are two special guests: Dr. Brunetta from the University of Campinas in Brazil, who holds a Ph.D. degree in Physiological Sciences, and Dr. Townsend, a CIHR Postdoctoral Researcher at McMaster University in Canada. Don't forget to subscribe and follow me on social media. You can find me on Instagram as @doctoref.rain and Facebook as Efrain Riveros-pérez. This conversation was based on the following articles: References: -Brunetta HS, Townsend LK. Muscle-fat crosstalk: effects of exercise on brown adipose tissue; what do we know? J Physiol. 2022 Sep;600(17):4039-4040. doi: 10.1113/JP283516. Epub 2022 Aug 6. PMID: 35866569. -Kim HJ, Kim YJ, Seong JK. AMP-activated protein kinase activation in skeletal muscle modulates exercise-induced uncoupled protein 1 expression in brown adipocyte in mouse model. J Physiol. 2022 May;600(10):2359-2376. doi: 10.1113/JP282999. Epub 2022 Apr 5. PMID: 35301717; PMCID: PMC9322297. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Struggling with Summer WORKOUTS in the HEAT? This advice can be a Game Changer. |Ep.27.
Apr 3 2024
Struggling with Summer WORKOUTS in the HEAT? This advice can be a Game Changer. |Ep.27.
In this episode, we explore the interesting area of body adaptations during exercise in the heat and explore strategies to optimize performance and tolerance under such conditions, just in time for the approaching summer. Joining us is Dr. Nathalie Kirby, an esteemed Research Scientist and Scientific Writer specializing in Human Physiology and Health. With a rich academic background and extensive research experience, Dr. Kirby sheds light on her latest study, which investigates the effects of intermittent post-exercise sauna bathing on exercise heat tolerance and performance markers. Specifically, her research aims to assess whether three weeks of endurance training combined with sauna bathing can enhance exercise heat tolerance and performance compared to endurance training alone, and whether further improvements occur with seven additional weeks of post-exercise sauna bathing. Don't forget to subscribe and follow me on social media. You can find me on Instagram as @doctoref.rain and Facebook as Efrain Riveros-pérez. This conversation was based in the following article: Reference: -Kirby NV, Lucas SJE, Armstrong OJ, Weaver SR, Lucas RAI. Intermittent post-exercise sauna bathing improves markers of exercise capacity in hot and temperate conditions in trained middle-distance runners. Eur J Appl Physiol. 2021 Feb;121(2):621-635. doi: 10.1007/s00421-020-04541-z. Epub 2020 Nov 19. PMID: 33211153; PMCID: PMC7862510. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
How can KETO reshape your LIPID PROFILE wellness?|Ep.26.
Mar 28 2024
How can KETO reshape your LIPID PROFILE wellness?|Ep.26.
In this video, I delve deep into the evidence surrounding the effects of a ketogenic diet on the lipid profile. Join me as I unravel the intricate biochemical pathways of cholesterol, shedding light on its significance in our health journey. Throughout the presentation, I meticulously discuss the optimal values of cholesterol and triglycerides crucial for averting atherosclerotic diseases and mitigating cardiovascular risks. Moreover, I explore the promising positive effects that embracing a ketogenic diet can exert on regulating cholesterol and triglyceride levels. From its potential in controlling lipid abnormalities to its role in normalizing the lipid profile, we uncover the transformative impact of ketogenic dietary strategies. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Is it possible to slow aging? Prioritizing your well-being as you age. | Ep. 25
Mar 20 2024
Is it possible to slow aging? Prioritizing your well-being as you age. | Ep. 25
In this episode, we'll be speaking with Dr. Adiv Johnson, PhD, Director of Research and Innovation at Tally Health, a company specializing in research on interventions that can slow aging. As stated on their website: 'We created Tally Health to bring decades of longevity science to the many, not the few.' In this episode, we discuss the factors that determine aging and healthy aging, as well as the measures we can take to slow down the aging process. Don't forget to share, like and subscribe! This conversation was based on the following article: Johnson AA, English BW, Shokhirev MN, Sinclair DA, Cuellar TL. Human age reversal: Fact or fiction? Aging Cell. 2022 Aug;21(8):e13664. doi: 10.1111/acel.13664. Epub 2022 Jul 2. PMID: 35778957; PMCID: PMC9381899. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
What is the best type of exercise to lose weight, and how can one maintain the achieved weight loss? |Ep.23
Mar 15 2024
What is the best type of exercise to lose weight, and how can one maintain the achieved weight loss? |Ep.23
In my inaugural solo episode, I will embark on a scientific exploration of weight loss. Together, we will delve into the various types of exercises, examining the evidence behind each and their impact on weight loss, aiding us in selecting the most effective method. Additionally, we'll delve into the pivotal role of exercise in addressing obesity. Furthermore, we will unravel the strategies necessary for maintaining our ideal weight once it's achieved. Throughout the episode, I'll touch on the metabolic effects of exercise, and at the end give some recommendations. I've included extracts of interviews with two experts: Dr. Vassilis Mougios, professor at Aristotle University in Greece, whose interview and entire discussion are presented in episode 1, and Dr. Gary Hunter, professor at the University of Alabama, who is my guest on episode 5. Thank you for supporting this journey to health and wellness based on scientific evidence. Don't forget to subscribe! Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Exploring the link between alcohol intake and obesity. |Ep. 22
Mar 6 2024
Exploring the link between alcohol intake and obesity. |Ep. 22
Join us in this insightful podcast episode as we delve into the complex relationship between alcohol intake and obesity. Our guest, Dr. Salma Rashid, a distinguished family doctor affiliated with the Ministry of Health in Muscat, Oman, brings her expertise to the discussion. Gain valuable insights, evidence-based perspectives to understand the association between alcohol consumption and obesity. Subscribe now for informed discussions on crucial topics with experts in the field! This episode was based in the following article! AlKalbani SR, Murrin C. The association between alcohol intake and obesity in a sample of the Irish adult population, a cross-sectional study. BMC Public Health. 2023 Oct 24;23(1):2075. doi: 10.1186/s12889-023-16946-4. PMID: 37875864; PMCID: PMC10594818. Also available at: Spotify, Apple Podcasts and Amazon Music as Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram and @dr.efrain on TikTok. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Heat for Health: Discover the healing power of the infrared sauna. |Ep. 21
Feb 28 2024
Heat for Health: Discover the healing power of the infrared sauna. |Ep. 21
In this insightful episode, Dr. E.F. Rain engages in a conversation with Dr. Joy Hussain, delving into the remarkable health benefits of infrared sauna therapy. Drawing comparisons with exercise, a well-established contributor to cardiovascular health and mental well-being, the discussion sheds light on the distinct advantages offered by infrared sauna sessions. Join us as we explore the expanding field of research surrounding sauna use, uncovering its potential to enhance recreation, foster social connections, and deliver tangible medical benefits. Discover how sauna therapy might not only be a source of relaxation and enjoyment but also a valuable component in the comprehensive management of various health conditions. Dr. Hussain is the Clinical Director of Health with Joy Pty Ltd, an integrative medical practice promoting wearables, wellness and evidence-based sauna therapies in Brisbane, Australia. In 2021, she completed her PhD at RMIT University on the topic of health effects of frequent sweating and sauna bathing. She is currently working to adapt sauna-based experimental protocols for lifestyle medical applications, such as in cardiovascular disease prevention, cardiac rehabilitation and treatment for postmenopausal hot flushes. This conversation was based on the following article: Hussain JN, Cohen MM, Mantri N, O'Malley CJ, Greaves RF. Infrared sauna as exercise-mimetic? Physiological responses to infrared sauna vs exercise in healthy women: A randomized controlled crossover trial. Complement Ther Med. 2022 Mar;64:102798. doi: 10.1016/j.ctim.2021.102798. Epub 2021 Dec 23. PMID: 34954348. Also available at: Spotify, Apple Podcasts and Amazon Music as Decoding Healthcare Research. - Dr.E.F.Rain as @dr.ef.rain on Instagram and @dr.efrain on TikTok. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
The role of nutrition and the microbiome in cancer treatment. |Ep.20
Feb 21 2024
The role of nutrition and the microbiome in cancer treatment. |Ep.20
In this episode, join the insightful conversation with Dr. E.F. Rain and Dr. K. Leigh Greathouse, Ph.D., Associate Professor of Nutrition Sciences at Baylor University. They delve into the profound impact of nutrition and diet on the microbiome. Discover how dietary choices influence the microbiome, altering its composition and influencing crucial aspects such as immunity, gut health, and gut permeability. Understanding these dynamics is crucial, as it unveils the potential for developing precision nutrition: a concept aimed at tailoring personalized and specialized diets for cancer patients. The objective is to enhance treatment responses, minimize toxic side effects, and achieve a more comprehensive management of cancer patients. The principles explored in this episode can also be applied to other inflammatory diseases. Dr. Greathouse, with her background in cancer biology, epidemiology, and nutrition, sheds light on the ongoing research in her laboratory at Baylor University. Her work, recognized with multiple awards, including a Merit Award from the National Institutes of Health, has positioned her as an expert in the field. Currently serving on the editorial board for Carcinogenesis and as an associate editor for Genetic Testing and Molecular Biomarkers, Dr. Greathouse is at the forefront of advancing our understanding of the intricate relationship between diet, the microbiome, and cancer etiology. Beyond academia, Dr. Greathouse is the CEO and Co-Founder of Greathouse Health LLC, a venture dedicated to developing tools to assist cancer patients in managing dietary, physical, and mental health challenges during and after cancer treatment. Don't miss this enlightening discussion that explores the intersection of nutrition, the microbiome, and personalized health strategies for cancer patients and beyond. This episode was based in the following article: Greathouse KL, Wyatt M, Johnson AJ, Toy EP, Khan JM, Dunn K, Clegg DJ, Reddy S. Diet-microbiome interactions in cancer treatment: Opportunities and challenges for precision nutrition in cancer. Neoplasia. 2022 Jul;29:100800. doi: 10.1016/j.neo.2022.100800. Epub 2022 Apr 29. PMID: 35500546; PMCID: PMC9065883. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
How exercise reduces the severity of obstructive sleep apnea? |Ep.19
Feb 14 2024
How exercise reduces the severity of obstructive sleep apnea? |Ep.19
In this episode, join the conversation with Dr. E.F. Raind and Dr. Ozeas de Lima Lins Filho. They will discuss how exercise can reduce the severity of symptoms in patients with obstructive sleep apnea. Dr. de Lima Lins holds a master's degree in physical education from the Federal University of Pernambuco and a doctorate in Health Sciences from the Faculty of Medical Sciences at the University of Pernambuco. He has a keen interest in the field of biomechanics, physical activity for the elderly, and physical exercise and sleep respiratory disorders with an emphasis on cardiovascular variables. Currently, he is a substitute professor in the Department of Physical Education at the Federal University of Pernambuco and the coordinator of research and extension for the physical education course at the Pernambucana School of Health. This episode was based in the following articles:Reference: Lins-Filho O, Porto Aguiar JL, Vieira de Almeida JR, Soares AH, Ritti-Dias R, Julia da Silva M, Pedrosa RP. Effect of exercise training on body composition in patients with obstructive sleep apnea: a systematic review and meta-analysis. Sleep Med. 2021 Nov;87:105-113. doi: 10.1016/j.sleep.2021.08.027. Epub 2021 Sep 3. PMID: 34547647. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion
Brain insulin sensitivity: why is it important? |Ep.18
Feb 7 2024
Brain insulin sensitivity: why is it important? |Ep.18
Join the insightful conversation in this episode with Dr. E.F. Rain and Dr. Stephanie Kullmann, Deputy Head of Metabolic Neuroimaging at the Institute for Diabetes Research and Metabolic Diseases (IDM), part of the Helmholtz Center Munich, University of Tübingen. Dr. Kullmann's research is dedicated to exploring neurobiological mechanisms related to obesity and diabetes in humans. Leveraging neuroimaging methods, particularly functional magnetic resonance imaging, and employing measures of peripheral metabolism, she is keen on assessing brain insulin action through intranasal insulin application. This approach allows for the investigation of the metabolic and cognitive consequences of brain insulin resistance. In this talk, we delve into the concept of brain insulin sensitivity and unravel why understanding this aspect opens a new window for further research. Dr. Kullmann sheds light on how this exploration could be beneficial for the development of innovative treatments for individuals grappling with metabolic syndrome and obesity. This episode was based in the following articles: Reference: Kullmann S, Goj T, Veit R, Fritsche L, Wagner L, Schneeweiss P, Hoene M, Hoffmann C, Machann J, Niess A, Preissl H, Birkenfeld AL, Peter A, Häring HU, Fritsche A, Moller A, Weigert C, Heni M. Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese. JCI Insight. 2022 Sep 22;7(18):e161498. doi: 10.1172/jci.insight.161498. PMID: 36134657; PMCID: PMC9675563. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion
Ketogenic diet in the management of dementia and Alzheimer's disease. |Ep.17
Jan 31 2024
Ketogenic diet in the management of dementia and Alzheimer's disease. |Ep.17
In this episode, join the conversation with Dr. E.F. Rain and Dr. Marta Rusek, a seasoned PhD Research Scientist at the Medical University of Lublin, Poland. With over 14 years of expertise in medical biology and biotechnology, Dr. Rusek specializes in the molecular mechanisms of Alzheimer's disease and connective tissue disorders. Discover how the ketogenic diet emerges as a potential alternative treatment for Alzheimer's and dementia. Dr. Rusek, also a Lecturer, shares insights gained from teaching Pathology, Physiology, Genetics, and Biochemistry to undergraduate Medical Sciences students. Don't miss this deep dive into medical science! This episode was based in the following articles: Reference: Rusek M, Pluta R, Ułamek-Kozioł M, Czuczwar SJ. Ketogenic Diet in Alzheimer's Disease. Int J Mol Sci. 2019 Aug 9;20(16):3892. doi: 10.3390/ijms20163892. PMID: 31405021; PMCID: PMC6720297. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion
Sudden Cardiac Arrest: What can be done to save more lives. |Ep.16
Jan 24 2024
Sudden Cardiac Arrest: What can be done to save more lives. |Ep.16
In this episode, join the conversation with Dr. E.F. Rain, Dr. Adrian Baranchuk, Professor of Medicine at Queen’s University, in Kingston, Canada, and Mario Bassi, a Medical Doctor candidate at the same institution. They delve into the sensitive and widely discussed topic of sudden cardiac arrests during sports events, specifically in soccer and basketball stadiums. The discussion revolves around the challenges associated with it and explores how deaths can be prevented by considering the conditions of the stadium and the event facility. Most importantly, they emphasize the significance of creating an effective chain of survival to promptly assist the person experiencing the attack with the proper equipment and trained personnel. From screening to pragmatic solutions, this episode raises awareness about an event that can impact anyone, not just athletes, at any moment. It goes beyond sports events and extends to individuals without previously detected conditions. Dr. Baranchuk is a member of numerous editorial boards (Europace, Annals of Noninvasive Electrocardiology, etc) and reviewer of several journals. He is currently the Editor-in-Chief of the Journal of Electrocardiology and JACC in Spanish. This conversation was based on the following article: Reference: Bassi MD, Farina JM, Bombau J, Fitz Maurice M, Bortman G, Nuñez E, Márquez M, Bornancini N, Baranchuk A. Sudden Cardiac Arrest in Basketball and Soccer Stadiums, the Role of Automated External Defibrillators: A Review. For the BELTRAN Study (BaskEtbaLl and soccer sTadiums: Registry on Automatic exterNal defibrillators). Arrhythm Electrophysiol Rev. 2023 Jan;12:e03. doi: 10.15420/aer.2022.30. PMID: 36845166; PMCID: PMC9945480. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
How the microbiome can affect your overall health and its effects on aging. |Ep.15
Jan 18 2024
How the microbiome can affect your overall health and its effects on aging. |Ep.15
In this episode join Dr. Riveros in the conversation with Dr. Dawn Bowdish, Associate Professor at McMaster and a Canada Research Chair in Aging & Immunity. They discuss the role of the gut microbiome and inflammation in health and disease, as well as the implications for how we age healthily. Dr. Bowdish started her lab at McMaster in 2009 where her team of post-doctoral fellows, undergraduate and graduate students study the process of macrophage phagocytosis, how macrophages influence the composition of the microbiome of the upper respiratory tract and how they recognize and destroy Streptococcus pneumoniae, the major cause of pneumonia in the elderly. She has won a number of early career awards including the Pfizer-ASPIRE award and the G. Jeannette Thorbecke Award from the Society of Leukocyte Biology. Her lab is funded by the CIHR, NSERC, the Labarge Optimal Aging Initiative and the Lung Association. This episode was based in the following articles: References: -Thevaranjan N, Puchta A, Schulz C, Naidoo A, Szamosi JC, Verschoor CP, Loukov D, Schenck LP, Jury J, Foley KP, Schertzer JD, Larché MJ, Davidson DJ, Verdú EF, Surette MG, Bowdish DME. Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction. Cell Host Microbe. 2017 Apr 12;21(4):455-466.e4. doi: 10.1016/j.chom.2017.03.002. Erratum in: Cell Host Microbe. 2018 Apr 11;23 (4):570. PMID: 28407483; PMCID: PMC5392495. -DeJong EN, Surette MG, Bowdish DME. The Gut Microbiota and Unhealthy Aging: Disentangling Cause from Consequence. Cell Host Microbe. 2020 Aug 12;28(2):180-189. doi: 10.1016/j.chom.2020.07.013. PMID: 32791111. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
How to overcome menopause challenges? |Ep.14
Jan 11 2024
How to overcome menopause challenges? |Ep.14
In this insightful episode, engage in a conversation with Dr. E.F. Rain and Dr. Victoria Vieira Potter, Associate Professor of Nutrition and Exercise Physiology at the University of Missouri, as they delve into the intricate aspects of menopause. Explore the crucial roles played by adipose tissue and estrogen in influencing metabolism, insulin sensitivity, and the array of symptoms associated with menopause. The discussion also encompasses practical measures women can adopt to alleviate menopausal symptoms and navigate this stage effectively. From exercise strategies to dietary considerations and insights into hormonal replacement, discover valuable approaches to enhance well-being during menopause. Dr. Vieira-Potter conducts primarily basic science studies, delving into mechanisms to prevent and treat obesity-related diseases. A major focus of her research revolves around understanding how exercise and estrogen influence adipose tissue metabolism, including the impact of estrogen loss on adipose tissue due to changes in physical activity behavior. In her work, she is actively forging collaborations with clinicians and scientists in the fields of neuroscience and psychiatry to further interrogate these questions, particularly in aging women. This episode was based in the following article: Reference: Marsh ML, Oliveira MN, Vieira-Potter VJ. Adipocyte Metabolism and Health after the Menopause: The Role of Exercise. Nutrients. 2023 Jan 14;15(2):444. doi: 10.3390/nu15020444. PMID: 36678314; PMCID: PMC9862030. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.
Your daily cup of coffee and tea could be helping you age better. |Ep.13
Jan 3 2024
Your daily cup of coffee and tea could be helping you age better. |Ep.13
In this episode, join the conversation with Dr. E.F. Rain and Dr. Woon Puay Koh. They discuss the benefits of daily consumption of coffee, black tea, or green tea and how it could actually be helping you age better. Dr. Koh is a Professor in the Healthy Longevity Translational Research Programme at Yong Loo Lin School of Medicine and a Joint-Professor at the Saw Swee Hock School of Public Health at the National University of Singapore. Prof. Koh is also a Senior Principal Investigator at the Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore. She is the Principal Investigator of the Singapore Chinese Health Study, a cohort of 63,257 middle-aged and elderly Chinese Singaporeans established for the long-term study of dietary and environmental determinants of chronic diseases among Singaporeans. She has co-authored over 450 scientific papers on diet, lifestyle, and genes in relation to the risk of diseases such as cancer, cardiovascular diseases, diabetes, gout, osteoporosis, osteoarthritis, and aging outcomes. The conversation was based on the following articles: Chua KY, Li H, Lim WS, Koh WP. Consumption of Coffee, Tea, and Caffeine at Midlife, and the Risk of Physical Frailty in Late Life. J Am Med Dir Assoc. 2023 Nov;24(11):1655-1662.e3. doi: 10.1016/j.jamda.2023.06.015. Epub 2023 Jul 21. PMID: 37488031. Follow us on social media! -Instagram and TikTok: @agora_health -Facebook Page: Agora Health -Spotify, Apple Podcasts and Amazon Music: Decoding Healthcare Research - Dr.E.F.Rain as @dr.ef.rain on Instagram. Disclosure: The content of this podcast is purely academic in nature and is intended for educational and informational purposes only. The material discussed does not represent or reflect the views, opinions, or policies of the Medical College of Georgia, and the information presented should not be construed as medical advice or guidance. Always consult with a qualified healthcare professional for any medical concerns or questions. I'd like to explicitly state that I have no endorsement from, affiliations with, or financial interests in any pharmaceutical companies or medical device manufacturers. Any mention of medications, devices, or treatments is made solely within the context of literature and academic discussion.