We're back, friends!  On this first episode of season 2, we answer the question, "what’s the update on variants and vaccine effectiveness?"  We kick things off with a snapshot of the overall COVID-19 case rate, mortality and hospitalization data, and vaccine uptake. Next, we define some terminology-- specifically the difference between efficacy and effectiveness. We then discuss clinical trial and real-world effectiveness data for the three vaccines currently in use in the United States (Pfizer, Moderna, and J&J). Of course, we had to talk boosters-- so we summarize the recent recommendations from the FDA and CDC, and what they mean for Americans. Next, we talk about Delta and some of the other variants that have people talking these days. We wrap things up by clarifying that vaccines do, in fact, prevent transmission of SARS-CoV-2 through a few different mechanisms including reduced viral load, shortened infectious period, and overall reduced risk of infection. We hope you enjoy! We have lots of exciting episodes lined up for this season so stay tuned! Learn more about your ad choices. Visit megaphone.fm/adchoices