Despite its controversial nature, the use of medical marijuana and marijuana-derived medicinal products grows more popular with each passing year. As of November 2018, over 40 states and multiple US Territories have passed legislation regarding the use of either medical marijuana or cannabidiol products and many providers have started encountering patients experimenting with cannabis products for a wide range of conditions. While the debate continues regarding these agents for both medicinal and recreational use in the general population, special consideration needs to be made for use in children and adolescents. This week's show will be a continuation of lasts week's show where we discussed the history of marijuana use and legislation in the United States in addition to the currently available medical literature to equip parents with resources the best recommendation for safe and appropriate use of cannabis-containing compounds.