Lab Rat Chat

Lab Rat Chat

A podcast dedicated to providing an accurate and alternate narrative to the public regarding the necessity of humane and ethical animal research. Lab Rat Chat was made possible through the Michael D. Hayre Fellowship in Public Outreach, which is sponsored by the biomedical research advocacy group Americans for Medical Progress. read less

31. Mastering Laboratory Animal Science
Jan 12 2023
31. Mastering Laboratory Animal Science
Lab Rat Chat - Episode 31 with Erin VogelsongIn this episode of Lab Rat Chat, Jeff and Danielle chat with Erin Vogelsong, MS, Program Director of Drexel University's Master of Laboratory Animal Science program.Special Live Webinar Announcement - February 1st @ 12pm EST:In celebration of International Laboratory Animal Technician Week, Drexel University is hosting a webinar Bringing the Magic Through Podcasting: A Behind the Scenes Look Into the Lab Rat Chat Podcast.  The webinar will feature Danielle Dady and Jeff Marshall, the hosts of Lab Rat Chat, and will give participants an inside look into the magic that goes into creating each and every episode. Tune in to learn more about the hosts, why Lab Rat Chat was created, the insider scoop on Jeff and Danielle’s favorite episodes, some of the mistakes made and lessons learned, and what to expect from Lab Rat Chat in the future. Visit Online.Drexel.Edu/LabRatChat to register. Topics discussed in this episode:Erin's extensive and impressive background and her journey to get where he's at in her career today.Some history and facts about Drexel's Master of Laboratory Animal Science programWhy anyone out there should consider advancing their education through this program and the potential benefits of doing so.Purchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Resources & Links:Master of Laboratory Animal Science MLAS - Drexel University College of MedicineDrexel University Online | Drexel OnlineAmericans for Medical ProgressAmericans for Medical Progress COVID-19 ResourcesFollow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
30. Marmosets: The (mon)Key to Understanding Alzheimer's Disease
Dec 14 2022
30. Marmosets: The (mon)Key to Understanding Alzheimer's Disease
Lab Rat Chat - Episode 30 with Dr. Agnès LacreuseIn this episode of Lab Rat Chat, Jeff and Danielle chat with Dr. Agnès Lacreuse, PhD, who is a researcher at the University of Massachusetts in the Department of Psychological and Brain Sciences Department.She utilizes nonhuman primates in her research in order to better understand neurocognitive aging and pathological aging processes, such as those involved in Alzheimer's disease. Two-thirds of Alzheimer's disease cases in humans are women. 2/3 of AD cases in humans are women. For this reason, we also aim to understand how changes in sex hormones, especially estrogens, affect brain and cognitive aging in females.Topics discussed in this episode:Dr. Lacreuse's extensive and impressive background and her journey to get where he's at in her career today.What Alzheimer's disease is, who is primarily affected, how it develops, and the estimated number of people living with the disease in the United States.Why nonhuman primates, particularly Marmosets, are best suited to study Alzheimer's compared to rodents, and why alternative models (e.g., organs on a chip, computer models, etc.) are not viable options.The future application of her research on the human population and what it means for those predisposed or already suffering from the devastating effects of Alzheimer's.Purchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Resources & Links:Animal models of Alzheimer’s disease embrace diversity | Lab Animal (nature.com)Americans for Medical ProgressAmericans for Medical Progress COVID-19 ResourcesFollow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
29. Sweet, Drunk Monkeys
Sep 23 2022
29. Sweet, Drunk Monkeys
Lab Rat Chat - Episode 29 with Dr. Kyle FlippoIn this episode of Lab Rat Chat, Jeff chats with Dr. Kyle Flippo, PhD, who is a postdoc in the University of Iowa Neuroscience and Pharmacology Department.   He studies the role of endocrine signaling in the CNS in regulating metabolism, amongst other things.  One of his current research projects has explored the role of a hormone (FGF21) in suppressing alcohol consumption in monkeys. Not only is this promising for providing a treatment for alcohol use disorders, they've also found this hormone plays a major role in reducing sugar intake as well.  This research is really groundbreaking stuff and thankfully we have scientists out there like Dr. Flippo who works compassionately with laboratory animals to make these sorts of discoveries.Topics discussed in this episode:Dr. Flippo's extensive and impressive background and his journey to get where he's at in her career today.The prevalence of alcoholism in the United States and why Dr. Flippo decided to pursue this area of research.Why vervet monkeys are best suited to study alcohol addiction compared to rodents and why alternative models (e.g., organs on a chip, computer models, etc.) are not viable options.The future application of this research on the human populationPurchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Resources & Links:A Molecule Tested in Higher Primates Reduced Alcohol Consumption By Half | Brain & Behavior Research Foundation (bbrfoundation.org)Americans for Medical ProgressAmericans for Medical Progress COVID-19 ResourcesFollow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
28. Autism-like Traits and Sleep Apnea
Aug 12 2022
28. Autism-like Traits and Sleep Apnea
Lab Rat Chat - Episode 28 with Dr. Amanda VanderplowIn this episode of Lab Rat Chat, Danielle and Jeff chat with Dr. Amanda Vanderplow, a PhD research scientist in the Cahill Lab of Neuroscience Research at the University of Wisconsin-Madison.   She studies dendritic spine plasticity and how synaptic alterations contribute to neuropsychiatric disorders.  In other words, she much smarter than the rest of us.  One of her current research projects discovers a potential link between sleep apnea and autism-like behaviors. This could be one of those breakthrough discoveries that allows us to prevent and/or reduce the rising prevalence of autism-like behaviors in society today, and we have Dr. Vanderplow, her team, and her rats, to thank for discovering this link. Topics discussed in this episode:Dr. Vanderplow's extensive and impressive background and her journey to get where she's at in her career today.What sleep apnea is and how prevalent the disorder is in society; the numbers will shock you.How a rat sleep apnea model was developed and how the data regarding autism-like behaviors in animals translate into the human world.The future application of this research and her recent discoveriesPurchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Resources & Links:Cahill Lab of Neuroscience Research – UW–Madison (wisc.edu)Mothers' sleep apnea may increase risk of autism-like changes in their male offspring (medicalxpress.com)Americans for Medical ProgressAmericans for Medical Progress COVID-19 ResourcesFollow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
News Bite - July 2022
Jul 21 2022
News Bite - July 2022
News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).In this News Bite edition, Jeff and Danielle discuss:A promising new drug to prevent and slow the progression of Parkinson's diseasePain relief in the form of implantable nerve cooling devicesHow sound and music can reduce both chronic and acute painDanielle's true calling in life, creating tiny adorable mouse villages Links to all these stories can be found below Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/                                         Purchase Lab Rat Chat merch and help support the podcast and biomedical research!https://labratchat.myteespring.co/Follow us on Twitter! Facebook! Instagram!             Resources & Links:New potential drug for Parkinson's -  https://www.science.org/content/article/experimental-drug-targets-early-stages-parkinson-sNerve cooling pain relief story - https://www.aaas.org/news/miniature-implantable-nerve-coolers-enable-targeted-pain-relief?adobe_mc=MCMID%3D41208732208569100191553672894342571103%7CMCORGID%3D242B6472541199F70A4C98A6%2540AdobeOrg%7CTS%3D1658425655Sound and pain relief - https://www.sciencedaily.com/releases/2022/05/220524100557.htmAnonymous miniature mouse displays - https://www.bostonglobe.com/2022/06/22/metro/swedish-art-group-anonymouse-installs-detailed-miniature-displays-around-boston/Tour an Animal Research LaboratoryAmericans for Medical Progress All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
News Bite - June 2022
Jun 23 2022
News Bite - June 2022
News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).In this News Bite edition, Jeff and Danielle discuss:The ability of animals to detect harsh speaking tonesBats and echolocationFirst-ever study showing that headbutting animals can and do suffer from traumatic brain injuriesA new incredible imaging technology to image the middle and inner ear Links to all these stories can be found below Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/                                         Purchase Lab Rat Chat merch and help support the podcast and biomedical research!https://labratchat.myteespring.co/Follow us on Twitter! Facebook! Instagram!             Resources & Links:Traumatic Brain Injuries and Headbutting Animals Story - https://www.google.com/amp/s/www.newsweek.com/head-cases-horned-animals-damage-their-brains-head-butting-each-other-say-scientists-1708397%3famp=1Middle Ear Imaging Technology Story - https://www.frontiersin.org/articles/10.3389/fphot.2022.929574/fullAnimals Interpretating Harsh Speaking Tones Story - https://www.sciencedaily.com/releases/2022/05/220524100557.htmBats and Echolocation Story - https://neuroscience.ucdavis.edu/news/bat-brains-organized-echolocation-and-flightTour an Animal Research LaboratoryAmericans for Medical Progress All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
27. The Bird is More than the Word, with Dr. Christine Lattin
Jun 1 2022
27. The Bird is More than the Word, with Dr. Christine Lattin
Lab Rat Chat - Episode 27 with Dr. Christine LattinIn this episode of Lab Rat Chat, Danielle and Jeff chat with Dr. Christine Lattin, an assistant professor at Louisiana State University.   She conducts incredible research using birds as a model to help our understanding of stress and how different neurotransmitters and hormones help wild animals successfully cope with challenges, from predators to disease.  Dr. Lattin's research will advance our understanding of how these hormone and neurotransmitter pathways work in humans as the pathways are very similar amongst all vertebrae species.  We also discuss an extensive and uncalled-for attack campaign by PETA on Dr. Lattin's research and personal life and how she's been able to continue to thrive and overcome these challenges.Topics discussed in this episode:Dr. Lattin's extensive and impressive background and her journey to get where she's at in her career today.Why and how birds are a critical model to use in order to understand her research interests.The future application of her research using birds and how it will be able to benefit humans and society.Why her research has been targeted by PETA, the extensive amount of work and money PETA has spent attacking her and her research, and how she's been able to adapt and overcome.Purchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Resources & Links:What Makes Some More Afraid of Change than Others? (lsu.edu)LSU Biologist Examines Animal Resilience To StressAmericans for Medical ProgressAmericans for Medical Progress COVID-19 ResourcesFollow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
News Bite - March 2022
Apr 1 2022
News Bite - March 2022
News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).In this News Bite edition, Jeff and Danielle discuss:How scientists have figured out a way to interpret pig grunts to reveal their emotionsJeff's lack of ability to pay attention to prior News Bite stories and re-tell a story from January about osteoarthritis (but, as a man with 4 kids, just happens to be able to make-up for it by having an additional story regarding male contraceptive research on hand and ready to go)The first ever genetic model of down syndrome in ratsThe mystifying way boa constrictors are able to breathe while squeezing their prey Links to all these stories can be found below Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/                                         Purchase Lab Rat Chat merch and help support the podcast and biomedical research!https://labratchat.myteespring.co/Follow us on Twitter! Facebook! Instagram!             Resources & Links:Researchers Figure Out How to Interpret Pig Grunts as Pig Emotions - CNETThe pill for men: Mice study shows 99% effectiveness (medicalnewstoday.com)To be thorough - Jeff's repeated story: Implant zaps the inside of the knee joint to stimulate the growth of cartilage | Daily Mail OnlineScientists Create Novel Genetic Model of Down Syndrome in Rats (hopkinsmedicine.org)How Boa Constrictors Breathe While Squeezing the Life Out of Their Prey | Science| Smithsonian MagazineTour an Animal Research LaboratoryAmericans for Medical Progress All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
26. Defeating Diabetes with Dr. Roy Taylor
Feb 10 2022
26. Defeating Diabetes with Dr. Roy Taylor
Lab Rat Chat - Episode 26 with Dr. Roy TaylorIn this episode of Lab Rat Chat, Danielle and Jeff chat with Dr. Roy Taylor,  a physician and author, who is currently the Director of Newcastle Magnetic Resonance Centre at Newcastle University.   He has been conducting research on type 2 diabetes since 1978 and in 2011, Taylor showed that the disease was a simple, reversible condition of excess fat within the liver and pancreas. Taylor developed the system now used throughout the United Kingdom for screening for diabetic eye disease, which has resulted in a major reduction in blindness due to diabetes across the UK. He is the author of Life Without Diabetes, a popular guide to understanding and reversing type 2 diabetes and achieving lasting remission (link below).Topics discussed in this episode:Dr. Taylor’s extensive and impressive background as a physician and scientist.What diabetes is and the differences between type 1 and type 2 diabetes.How the use of animals in his early research was crucial in order to understand the disease process.The role of physicians in not only managing their patients through the use of medicine, but in ways to prevent and/or cure their condition through diet and exercise.Purchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/ Resources & Links:Dr. Taylor’s Book: Life Without Diabetes: The Definitive Guide to Understanding and Reversing Type 2 DiabetesReversing Type 2 Diabetes - Newcastle Magnetic Resonance Centre - Newcastle University (ncl.ac.uk)Americans for Medical ProgressAmericans for Medical Progress COVID-19 ResourcesFollow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show
25. Monkey Business
Nov 30 2021
25. Monkey Business
Lab Rat Chat - Episode 25 with Lindsay BaderPurchase Lab Rat Chat merch and help support our podcast and biomedical research!https://labratchat.myteespring.co/In this episode of Lab Rat Chat, Danielle and Jeff chat with Lindsay Bader, who is a Senior Research Associate at the Oregon National Primate Research Center.   Lindsay has a ton of hands-on experience  working with many different species of monkeys .  She's been deeply involved in the research as well the animal care and husbandry components that go along with it, and has a wealth of information to share about what it's like working with monkeys in laboratory environments.Topics discussed in this episode:Lindsay's extensive and impressive background working with monkeys in research settings.The types of research that goes on at the Oregon National Primate Research Center and the types of animals they have.How and why enrichment is so important, especially when working specifically with monkeys in research.The many complexities that are involved in trying to house compatible groups of monkeys together.The impacts certain activities, such as feeding animals treats that are on restricted or controlled diets, can have on research data. Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Follow us on Twitter! Facebook! Instagram!https://twitter.com/thelabratchat https://www.facebook.com/labratchat https://www.instagram.com/thelabratchat Resources & Links:Caring for Our Animals | OHSUAmericans for Medical Progress (https://www.amprogress.org/) Americans for Medical Progress COVID-19 Resources (https://www.amprogress.org/covid-19-resources/)All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/  Support the show
News Bite - October 2021
Oct 25 2021
News Bite - October 2021
News Bites are monthly episodes where Danielle and Jeff break down important topics surrounding the field of biomedical research (and some unrelated topics).Purchase Lab Rat Chat merch and help support the podcast and biomedical research!https://labratchat.myteespring.co/In this News Bite edition, Jeff and Danielle discuss:In recognition of October being Breast Cancer Awareness Month, we discuss a new method to treat aggressive forms of breast cancer.A new molecule that can act as a 'Trojan horse' for cancer cells - activated by light and destroying the cell, while leaving healthy cells unaffected.The first ever pig to human kidney transplant - a huge milestone!The best tardigrade (aka water bear or moss piglet) fossil to ever be found and where you can go see it for yourself. Links to all these stories can be found below Sign up for the Lab Rat Chat newsletter!https://www.amprogress.org/raising-voices/lab-rat-chat/Follow us on Twitter! Facebook! Instagram!                                                                Resources & Links:Scientists identify a new method to treat triple-negative breast cancer (news-medical.net)Photoactivatable Metabolic Warheads: Light-Sensitive Drug Acts As Trojan Horse to Kill Cancer Cells (scitechdaily.com)A pig kidney has been transplanted into a human successfully for the first time : NPRFossilized Tardigrade Trapped in Amber Found in the Dominican Republic (businessinsider.com)Tour a Animal Research LaboratoryAmericans for Medical Progress All Lab Rat Chat episodes are edited by Audionauts: https://audionauts.pro/ Support the show