Dive deep into the fascinating world of brain health, brain mapping, and the game-changing impact of neurofeedback on anxiety, sleep, executive function, and so much more.  In this episode, Dr. Andrew Hill - a neuroscientist with a Ph.D. in Cognitive Neuroscience from UCLA and is best known as an expert neurofeedback practitioner and brain fitness coach - shares his decades of knowledge to help us understand the power of neurofeedback. Discover the pivotal role of brain mapping in tailoring personalized neurofeedback treatments, how certain brainwaves in different areas of the brain affect your cognition, and what you can do to optimize sleeping patterns, reduce anxiety, and even IMPROVE your social skills! Discover the nuanced impact of brainwaves like theta and beta waves on cognition. Explore how focusing on these waves can optimize specific areas of your health, from enhancing executive function to reducing anxiety and improving sleep patterns. Join us for an eye-opening journey into brain health and neurofeedback. - Use code “SELFDECODE” to get 50% off unlimited brain mapping at https://peakbraininstitute.com/ - Follow @peakbrainla on Instagram - Check out SelfDecode - Join Joe’s online community

Dive into the world of immunity optimization with Joe and Siim Land - all the way from India! From supplement stacks to proactive measures for bolstering the immune system, Siim and Joe dissect their distinct immune-boosting protocols aimed at fortifying immunity and enhancing the body's defense mechanisms. Joe and Siim share their tailored approaches to prevent illness and expedite recovery when under the weather.  Gain exclusive insights into their supplement regimens, tailored to optimize immune response and foster resilience against sickness. Highlighting key lab markers crucial for optimizing health, Joe and Siim also shed light on the pivotal metrics they prioritize, uncovering the essential lab markers important for monitoring and fine-tuning immune function. - Check out SelfDecode - Join Joe’s online community - Follow Siim Land on Instagram

Unlock the mysteries behind methylation, MTHFR, and homocysteine! Join us as we dive into these widely recognized yet often misunderstood terms that impact heart health, mental well-being, fertility, and more. The surge in popularity around methylation, MTHFR, and homocysteine has led to a barrage of misinformation.  In this enlightening episode, we've invited Dr. Denise Furness, a distinguished molecular geneticist boasting over two decades of expertise in folate nutrigenomics, methylation, and DNA damage. Join us for a wealth of game-changing insights as Denise delves deep into: Understanding methylation's pivotal role in your health Unraveling the impact of the MTHFR gene on methylation levels Optimal homocysteine levels and their significance Essential lab markers for optimizing your health Debunking concerns about over-methylation - Check out SelfDecode - Join Joe’s online community

I’m thrilled to be back with a brand-new season of The Joe Cohen Show!  We’re kicking off the season with truly life-changing knowledge with a popular returning guest, Dr. Oz Garcia! In this episode, Dr. Oz Garcia and I explore the keys to happiness, the transformative power of meditation, and the world of biohacking for pain reduction and sleep optimization! We dive into the intricacies of mood, discussing all the different pathways that affect your overall mood and the different approaches to consider depending on your unique biology. Are you dependent on serotonin for improved mood? Is your GABA pathway the culprit for your bad days? What about the vagus nerve? Dr. Oz highlights how treatments are completely different based on your body's needs! As the conversation unfolds, you'll find yourself immersed in discussions about mood and pain, as Dr. Oz shares some of his secret supplements and lifestyle hacks that reduce his pain and allow him to continue doing all the physical activities that he loves.

In this special episode, we've curated the most influential moments and expert insights from some of our remarkable guests of Season 4. Get ready to uncover a treasure trove of tips and tricks to supercharge your health and well-being. From optimizing gut health to longevity secrets, this episode is your ultimate guide to living your best, healthiest life. Tune in now for a power-packed journey into the world of wellness and discovery. Don't miss out on this collection of wisdom from the best in the field!

Have you ever wondered if a single gene could hold the key to unlocking your cognitive potential, or perhaps, be the culprit behind those moments of brain fog? Discover the fascinating world of the BDNF gene in this episode of SNPits.  Explore how your genetic makeup can impact your cognitive function and memory and uncover the association between BDNF variants and brain health.  Plus, learn how to naturally boost your BDNF levels for improved learning and mental performance.

Do you find it hard to drift off to sleep at night? Wondering why some nights are filled with vivid dreams while others leave you feeling like you've barely closed your eyes? What's the true impact of those late-night screens and the foods we consume on our sleep cycle? In this episode, Joe and Dr. Greg answers questions unraveling the mysteries of sleep and revealing the intricacies of our body's internal clock. Together, they explore the pivotal role of sleep in our overall health, spotlighting specific genes that might influence your sleep patterns and how you can modify your habits for a restful night. Shifting their attention to nutrients and dietary habits, they identify certain foods and minerals that promote sleep, like tryptophan and melatonin. From understanding genes like PER and CLOCK that regulate our circadian rhythms, to the essential role of diet, this episode is a comprehensive exploration of the science behind sleep! - Check out SelfDecode - Join Joe’s online community Timestamps: (0:00) - Intro (7:10) - Why do sleep disorders increase with age? (7:45) - How can I easily fall asleep? (14:56) - sleeping a lot but still tired (18:09) - Waking up in the middle of the night (26:54) - Waking up panicked (30:32) - Is there a way to increase slow wave sleep? (33:21) - Can SAD bring on insomnia? (34:43) - melatonin genes and sleep (36:28) - inconsistencies in sleep? (37:17) - how do I make sleep more restorative (38:35) - Is napping okay? (40:32) - How to increase REM sleep time?

In this episode of the Joe Cohen Show, we dive deep with renowned nutritionist Dr. Oz Garcia. With a lifetime of experience in the realm of nutrition, Oz shares his transformational journey from being a "rockstar nutritionist" to confronting the challenges of his own health issues. We explore the importance of not just focusing on what we eat, but also delving into data-driven wellness practices that can pave the path to optimal health. Learn about the markers and biomarkers that matter, how to achieve resilience in the face of illness, and why a data-driven approach is the key to unlocking true health. Whether you're a health enthusiast or a professional in the field, this conversation with Oz Garcia is an essential guide to elevating your nutrition strategy and achieving optimal health. - visit ozgarcia.com  - Follow Oz @ozwellness - Check out SelfDecode - Join Joe’s online community Timestamps: (0:00) - Intro (1:52) - Oz's process in helping a client get healthy (18:56) - Changing the way we look at health (34:59) - Supplements and reading lab levels (53:27) - Meditation and spiritual practices

The pursuit of optimal health is a lifelong journey, so finding the motivation to continue to make the right decisions can sometimes be difficult. If you’re not working on a tangible goal - like running a marathon or reaching a PR in squats - then how can you keep yourself from falling into unhealthy habits? In this episode, Andrew Steele - former Olympian and co-founder of DNAfit and Aila - and Joe share tips on how to set realistic goals that keep you striving for optimal health and performance. Andrew discusses the importance of health trackers in understanding your next steps, and shares how you can start becoming more aware of your diet and supplement changes to fuel you on your road to optimal health. Both Joe and Andrew share their lifechanging journey with genetics, and how they’re now incorporating labs to get a holistic picture of their health. - Visit https://meetaila.com/ - Check out SelfDecode - Join Joe’s online community

Chronologically, you get 1 year older every year. But how old are you getting biologically? In order to optimize longevity, you need to understand biological aging. With all the different longevity and biological aging tests, it can be difficult to understand where to start. Fortunately, we got Ryan Smith from Tru Diagnostic on todays episode to guide you on all things longevity and biological aging. In this episode, Ryan highlights the different biological aging tests and which one is the most accurate. He also gives helpful tips on how to reduce your pace of aging, and how that’s important for your overall lifespan. Ryan Smith is founder of TruDiagnostic, which has created the largest private epigenetic database in the world with over 25,000 patients tested. From this dataset, they have created many new algorithms to interpret methylation data including algorithms to predict inflammatory markers, disease diagnosis, telomere length, aging pace, immune cell subsets, cellular replication, and more. - Visit trudiagnostic.com - Check out SelfDecode - Join Joe’s online community Timestamps: (0:00) - Intro (1:48) - Where does epigenetics fall into aging biomarkers? (21:52) - Different responses in anti-aging protocols (39:44) - epigenetic test vs lab tests (48:42) - How to use biological age tests to improve health (55:09) - pace of aging (1:05:15) - Immune system age (1:09:11) - How to reduce the pace of aging (1:26:39) - How many supplements does Ryan take per day? (1:35:42) - Metformin and rapamycin on aging

Is the ApoE gene solely a predictor of cognitive decline, or is it just one piece of a larger, more intricate puzzle? In today's episode, we focus on the ApoE gene, a genetic player that’s most notoriously linked to Alzheimer's Disease. Julia dives deep into the three major variants called E2, E3, and E4, discussing how they change the shape of the ApoE protein and impact how well it functions. she  also opens up the curtain on other health issues that can be caused by the ApoE gene —impacting your cardiovascular health, your body's inflammatory responses, and even your longevity. Join us as we explore the layers of ApoE, debunk misconceptions, and discuss how understanding this gene could be a key step in taking control of your cognitive and overall health. Whether you're a genetic novice or a seasoned veteran in the world of SNPs, this episode will provide a comprehensive, yet easy-to-understand look into the multi-faceted role of the ApoE gene.

Why are there so many different versions of the same supplement? Is it all just a marketing ploy, or do they all have different effects on your health? In this episode, Emiel Bakker from Nootropics Depot comes on to dive into the complex world of dietary supplements, where not all products are created equal. He gives us an inside look at the science behind developing a supplement, from deciding on an extraction method to choosing between a fruiting body vs. mycelium. We uncover the nuanced factors that influence the efficacy and effects of some popular supplements, including: Lions Mane: How can different extraction methods affect its cognitive benefits? Bacopa: How to navigate its varieties for optimal memory enhancement. Saffron: Its antidepressant effects and the factors that contribute to its potency. Ubiquinol vs CoQ10: The dynamic duo of cellular energy—what's the difference and why does it matter? And more! Emiel Bakker is the product specialist at Nootropics Depot and Natrium Health, a company specializing in creating the best nootropic powders and capsules online. They offer pure nootropics and dietary supplements at the best prices. - Visit Nootropics Depot website - Find Emiel @prettychill_nd - Check out SelfDecode - Join Joe’s online community Timestamps: (0:00) - Intro (2:07) - Different variations of the same supplement (17:21) - Erinacine A and Lion’s Mane (19:57) - Pregnenalone (26:51) - Tetrahydromagnolol and Magnolia Bark (40:36) - How SelfDecode helps you understand supplements (42:29) - Bacopa for Serotonin (57:58) - Different effects of Maca (1:09:28) - Oroxylin A and effects on cognition (1:13:53) - Effects of Saffron (1:20:28) - How many supplements do you take a day? (1:22:33) - Ubiquinol vs CoQ10 (1:24:29) - Licorice Extract

How can you measure autophagy for certain? And what are the key stages to an effective fasting regimen? Returning guest, Dr. Joseph Antoun from L-Nutra, the visionary company spearheading the fast-mimicking diet revolution, is here to answer these questions. In this enlightening conversation, we delve into: New clinical trials that prove the fast-mimicking diet not only mimics fasting but enhances the benefits. The science of autophagy: What it is, its tremendous health benefits, and groundbreaking methods for measuring it—no more guesswork! The three stages of fasting, and how you can reach each one for optimal health benefits Dr. Antoun's recommended frequency for a 5-day fasting regime per year—because timing is everything. How to nail intermittent fasting and incorporate it seamlessly into your life. A deep dive into clinical trials that show the fasting mimicking diet can actually reverse diabetes. And so much more! Dr. Joseph Antoun is the CEO & Chairman of the Board of L-Nutra and a Member of the Forbes Business Development Council. He is also the former CEO of Health Systems Reform, an organization committed to optimizing public health. - Get 20% OFF All Products at https://l-nutra.com/ by using Code “JOE20” - Check out SelfDecode - Join Joe’s online community Timestamps: (0:00) - Intro (2:58) - Fasting mimicking diet best benefits (5:12) - Discussing autophagy (23:58) - Recommended number of times to fast (26:10) - Fasting for diabetes (28:27) - How to properly do intermittent fasting (42:00) - Nutrient sensing (47:43) - Theories on stem cells (50:02) - Clinical trials supporting fasting mimicking (54:57) - Biological aging tests (1:07:56) - Does Joseph take supplements?

Welcome back to SNPits, a short form series helping you decode your DNA, one gene at a time.  In this episode, we delve into the fascinating world of the COMT gene, commonly dubbed the "Warrior/Worrier" gene. We unpack the science behind this gene's influence on stress regulation, emotional resilience, and even cognitive function.  Is the "Warrior/Worrier" label an oversimplification, or does it offer a genuine glimpse into our genetic predisposition? Whether you're well-versed in genetics or just taking your first steps into this fascinating realm, today's episode promises to be an intriguing exploration of the role genes play in shaping our reactions to life's challenges. Links: The warrior variant and its effects on stress and working memory [R, R, R, R] The worrier variant and its effects on stress and emotional resilience [R, R, R, R, R].

Join us as we dive deep into the world of genomics, nutrition, and precision health with Dr. Greg Nacarelli, a leading expert in naturopathic medicine and genetics.  Dr. Nacarelli delves into the intricate interplay of genetics, environment, and lifestyle on our health, explaining why personalizing health care is the future. Greg touches on the value of understanding individual genetic profiles and how this can be utilized for personalized nutrition and health coaching.  With extensive academic qualifications and years of experience working with SelfDecode, Greg brings a unique blend of expertise to the table.  Whether you're a health professional or just a health enthusiast, this episode offers invaluable insights into the cutting-edge world of genomics and how it's shaping the future of personalized medicine.  Timestamps: (0:00) - Intro (2:53) - Practitioners Course (8:09) - How A Health Practitioner Uses SelfDecode (16:55) - Using the recommendations feature (25:44) - Continuing the health practitioners use of SelfDecode

Dive deep into the intricate world of gut health with the pioneer himself, Dr. Steven Gundry.  Once dismissed as pseudoscience, the concept of 'leaky gut' has become a cornerstone of modern health understanding, and no one knows this better than Dr. Gundry.  In this enlightening episode, we unravel the real science behind leaky gut, the dangers of food sensitivities, and the profound effects of glyphosate on our system.  Beyond just understanding, Dr. Gundry shares actionable insights on optimizing your gut health to transform your overall well-being.  Whether you're a long-time health enthusiast or just beginning your journey, this episode offers a treasure trove of knowledge. Timestamps: (0:00) - Introduction (3:30) - Dr. Gundry's current ideal diet (9:12) - Autoimmune Disease Reversal & Leaky Gut  (17:08) - IgG Antibodies (27:29) - Other markers attributed to leaky gut (34:14) - Glyphosate and linoleic acid (48:20) - Top things to counteract food sensitivities (54:23) - LPa, ApoB and LDL Cholesterol (1:02:09) - Thoughts on diet studies with beans and whole grains (1:05:44) - Protein Restriction & Intermittent Fasting (1:11:08) - Fibers and gas

Welcome to SNPits, a new, short-form podcast series that takes you on a deep dive into specific genes, unraveling the science behind them and their impact on health.  In this episode, we tackle the MTHFR gene and its rise to fame. We explore how 'typos' in our genes, known as SNPs, influence our health, and dive into the debate surrounding one of the most studied genes in the world.  Is the MTHFR gene truly a culprit in conditions like heart disease and chronic fatigue, or is it a scapegoat?  Join us as we decode the science, bust some myths, and take a closer look at how our genes really affect our health. Whether you're a genetics guru or new to the subject, this episode offers an insightful and entertaining look at the complexity of our genetic code.  Links: Some studies found a 35-70% reduction in enzyme activity [R], and links between MTHFR variants, higher homocysteine, and: Heart disease and stroke [R, R] Fertility and pregnancy issues [R, R, R, R, R, R] Mental health issues [R] Migraines with aura [R, R] Some studies found no evidence for these links. Some even found the opposite results. In one study, MTHFR variants were linked to a lower risk of death from heart disease [R, R, R, R, R]

To celebrate the richness of this season, we've compiled the most powerful insights and the unforgettable moments into a special "Best of Season 3" episode. From experts breaking down complex health subjects to invaluable pieces of advice on achieving your healthiest self, this episode is your ultimate guide to the knowledge treasure of Season 3.

Is anxiety truly genetic? How do our genes and environment shape our response to stress? Are we all experiencing the world differently based on our unique biochemical make-up?  In this episode, Joe and Dr. Greg (SelfDecode Health Expert) dive deep into the realm of anxiety, answering questions from the SelfDecode community and unmasking the role our brain's biochemistry plays in the expression of anxiety. Joe and Greg discuss the role of mental health in overall wellness and highlight specific genes that you can look at to potentially help you get rid of anxiety. They then focus on the nutrients most commonly depleted under chronic stress and their links to anxiety, and break down some herbal supplements that work wonders in balancing our brain's neurotransmitters.  From the influence of specific genes like COMT and MTHFR, to the vital role of minerals like magnesium, zinc, and vitamin B6, this episode is a deep dive into the science of anxiety!

What’s the difference between genomics and genetics? How important is it to understand your genes when looking at optimizing your health? In this episode, Dr. Anil Bajnath and Joe delve into the world of DNA and their impact on our health. Dr. Bajnath breaks down complex health science concepts in a way that's easy to understand, while sharing his unique approach to healthcare. Some highlights of the episode include: ✔️ Understanding the difference between genomics (the study of all genes in our body) and genetics (the study of inherited traits). ✔️ The role of transcriptomics (how our genes behave) in understanding health issues like PTSD. ✔️ The impact of our gut health on our overall wellbeing. ✔️ The potential dangers of over-reliance on certain medications like statins. ✔️ The relevance of understanding lipid dynamics (how fat works in our bodies) for our heart health. ✔️ The value of a holistic approach to healthcare - focusing on treating the whole person, not just symptoms. Dr. Anil Bajnath is a Board-Certified Family Physician. Author of The Longevity Equation: The Step-By-Step Blueprint to Hack Your Genes, Optimize Your Health, And Master the Art of Existence. Dr.Bajnath currently serves as Adjunct Faculty with the Department of Clinical Research and Leadership at George Washington University School of Medicine. He is the CEO and founder of the Institute for Human Optimization Precision Medicine Research Group located in Annapolis, Maryland.