Portrait artist Karin Merx is the host of Art Talk Podcast. The show features guests who are artists, art curators, or art collectors. The host also talks art with art historians, gallerists and art critics. In other episodes, Karin shares her opinions about specific topics in the world of art. Fine arts, modern art, and visual arts get discussed here. For example, in one episode, she discusses color theory and the importance of knowing how to use oil-based paints.

Each episode begins with slow acoustic guitar music. Whether Karin is alone or with a guest, the talk on this art podcast is serious but quiet. In one solo episode, Karin talks about how she believes there has been a decline in art education. She reads from an article on the subject. Karin says that art education no longer focuses on teaching technical skills. The host feels there is too much praise of the vague "creativity." The passage she quotes says that contemporary art is "pleased with itself." It also says that art education has "placed itself beyond criticism."

Curator Natalie Rigby is the guest on another Art Talk Podcast episode. She and Karin discuss storytelling through portraiture and art in general. Natalie encourages people to start conversations when looking at art. She names elitism as an obstruction. The guest celebrates artist Barbara Hepworth for making art that encourages interaction.

In another episode, Karin talks to Laura O'Hare, a director at the Visual Artists Association. The two discuss how showing one's authentic self is the best way to market one's art. Karin says she is enthusiastic when she is talking about her own work. This energy engages people and helps them appreciate her art.

Karin values art education and feels that formal training is essential. Fine arts, modern art, and visual arts get discussed here, and the host wants listeners to understand it. Listeners at all levels of art history knowledge may find value in the Art Talk Podcast. Before the outro music of each episode, Karin reminds listeners that art is the cradle of the soul.