VerifiedRx

Vizient Center for Pharmacy Practice Excellence

Delivering short doses of insight for hospitals’ frontline pharmacists, Vizient pharmacy leader Gretchen Brummel brings together experts to verify best practices for navigating today’s pharmacy practice challenges and accelerating career growth. It’s a prescription for success, delivered by the Vizient Center for Pharmacy Practice Excellence.

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Could this be the - plase? Tenecteplase or alteplase for acute ischemic stroke, part 2
Aug 9 2022
Could this be the - plase? Tenecteplase or alteplase for acute ischemic stroke, part 2
Dr. James Braun, Neurosciences Pharmacy Clinical Specialist at SSM Health St. Louis, and Dr. Kyle Hoelting, Senior Manager of Drug Information at Vizient, continue to share their insights on the use of TNK vs Alteplase for treating acute ischemic stroke. They also discuss the nuances of this therapeutic area and share recent work from an expert panel led by Vizient.   Guest speakers: James Braun, PharmD, BCCCP Neurosciences Pharmacy Clinical Specialist  SSM Health   Kyle Hoelting, PharmD, BCPS Senior Manager of Drug Information  Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:30-3:59] Medication safety risks associated with thrombolytics [04:00-4:42] Using one drug over another [04:43-6:48] How frontline pharmacy staff can utilize this information [06:49-11:44] What Vizient can add to the discussion [11:45-11:55] When report will be released   Links | Resources: Tenecteplase vs alteplase in acute ischemic stroke: Vizient expert panel Verified Rx: Evidenced based medicine Click here Verified Rx: Show me the data! Updates on the evidence of thrombolytic use in ischemic strokes Click here Verified Rx: Information overload: tips and tricks for staying on top of the literature, part 1 Click here Verified Rx: Information overload: tips and tricks for staying on top of the literature, part 2 Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Could this be the - plase? Tenecteplase or alteplase for acute ischemic stroke, part 2
Aug 9 2022
Could this be the - plase? Tenecteplase or alteplase for acute ischemic stroke, part 2
Dr. James Braun, Neurosciences Pharmacy Clinical Specialist at SSM Health St. Louis, and Dr. Kyle Hoelting, Senior Manager of Drug Information at Vizient, continue to share their insights on the use of TNK vs Alteplase for treating acute ischemic stroke. They also discuss the nuances of this therapeutic area and share recent work from an expert panel led by Vizient.   Guest speakers: James Braun, PharmD, BCCCP Neurosciences Pharmacy Clinical Specialist  SSM Health   Kyle Hoelting, PharmD, BCPS Senior Manager of Drug Information  Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:30-3:59] Medication safety risks associated with thrombolytics [04:00-4:42] Using one drug over another [04:43-6:48] How frontline pharmacy staff can utilize this information [06:49-11:44] What Vizient can add to the discussion [11:45-11:55] When report will be released   Links | Resources: Tenecteplase vs alteplase in acute ischemic stroke: Vizient expert panel Verified Rx: Evidenced based medicine Click here Verified Rx: Show me the data! Updates on the evidence of thrombolytic use in ischemic strokes Click here Verified Rx: Information overload: tips and tricks for staying on top of the literature, part 1 Click here Verified Rx: Information overload: tips and tricks for staying on top of the literature, part 2 Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Could this be the - plase? Tenecteplase or alteplase for acute ischemic stroke, part 1
Jul 12 2022
Could this be the - plase? Tenecteplase or alteplase for acute ischemic stroke, part 1
Dr. James Braun, Neurosciences Pharmacy Clinical Specialist at SSM Health St. Louis, and Dr. Kyle Hoelting, Senior Manager of Drug Information at Vizient, share their insights on the use of tenecteplase vs alteplase for treating acute ischemic stroke. They also discuss the nuances of this therapeutic area and share recent work from an expert panel led by Vizient.   Guest speakers: James Braun, PharmD, BCCCP Neurosciences Pharmacy Clinical Specialist  SSM Health   Kyle Hoelting, PharmD, BCPS Senior Manager of Drug Information  Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:58-3:00] James’ background and his role in the treatment of stroke patients [03:01-5:09] History of tenecteplase and alteplase for ischemic stroke [05:10-6:56] Information about trials of alteplase [06:57-8:11] Where Tenecteplase fits in discussion [08:12-9:51] Differences with tenecteplase and alteplase to clinicians [9:52-12:00] What studies say about potential, practical advantages of tenecteplase [12:01-19:55] Making the switch between agents   Links | Resources: Verified Rx: Evidenced based medicine Click here Verified Rx: Show me the data! Updates on the evidence of thrombolytic use in ischemic strokes Click here Verified Rx: Information overload: tips and tricks for staying on top of the literature, part 1 Click here Verified Rx: Information overload: tips and tricks for staying on top of the literature, part 2 Click here Identifying errors and safety considerations in patients undergoing thrombolysis in acute ischemic stroke Click here EXTEND-IA TNK Click here Australian-TNK Click here Meta-analysis NIHSS outcomes Click here NOR-TEST Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Vizient Pharmacy Vision Awards: Mark A. Johnson excellence in pharmacy analytics
Jun 28 2022
Vizient Pharmacy Vision Awards: Mark A. Johnson excellence in pharmacy analytics
Dr. David Aguero, Director, Medication Systems and Informatics, and Dr. Ben Moore, Pharmaceutical Data Analytics Coordinator at St. Jude Children’s Research Hospital winners of the Vizient Pharmacy Vision Award for excellence in pharmacy analytics, discuss their program that used analytics to design a program that positioned pharmacy as an internal service line with defined business goals with host Gretchen Brummel.   Guest speakers: David Aguero, PharmD, MSTL, dPLA Director, Medication Systems and Informatics  St. Jude Children’s Research Hospital Ben Moore, PharmD, MS Pharmaceutical Data Analytics Coordinator  St. Jude Children’s Research Hospital Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [01:13-2:42] Background information on pharmaceutical services, informatics, analytics team at St Jude [02:43-5:23] Building the governance structure at St. Jude [05:24-7:39] The problem that needed solving [07:40-10:00] Ultimately, what did they want to accomplish [10:01-13:58] Approaches that address the issues     [13:59-16:25] Deliverables they were able to reduce as part of this work, and who are their end users [16:26-18:03] Discovering other opportunities [18:04-19:48] Outcomes from the work [19:49-20:44] Role of analytics in health care, specifically in pharmacy [20:45-21:29] Future plans [21:30-22:37] Advice for frontline pharmacy staff   Links | Resources: Vizient Pharmacy Vision Awards: Click here Video All winners   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Vizient Pharmacy Vision Awards: excellence in clinical pharmacy practice
Jun 21 2022
Vizient Pharmacy Vision Awards: excellence in clinical pharmacy practice
Dr. Shirley Wong, Clinical Program Pharmacist, and Dr. Stephanie Hsia, Assistant Professor of Clinical Pharmacy at UCSF, winners of the Vizient Pharmacy Vision Award for Excellence in clinical practice, discuss their program helped UCSF to reach a system wide goal of 73% blood pressure control in our African American population and close the disparity in hypertension control with host Gretchen Brummel.   Guest speakers: Shirley Wong, PharmD, CGP Clinical Program Pharmacist  UCSF   Stephanie Hsia, PharmD, MAEd, BCPS, BCPP Assistant Professor of Clinical Pharmacy  UCSF   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [01:01-2:15] What were they trying to accomplish [02:16-6:14] Approach to address the problem [06:15-6:55] What's included in their collaborative practice agreement [06:56-08:37] Pharmacist training requirements to provide these services [08:38-09:55] Impact of the work on patient outcomes     [09:56-11:49] Other opportunities discovered along the way [11:50-12:58] Are successes going to encourage other tele-pharmacy programs [12:59-14:18] Other ways this program influenced patient satisfaction [14:19-14:50] Future plans [14:51-15:54] Advice for frontline pharmacy staff   Links | Resources: Vizient Pharmacy Vision Awards: Click here Video - award winners   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Cybersecurity and downtime preparedness in health system pharmacy: when it happens to you
Apr 12 2022
Cybersecurity and downtime preparedness in health system pharmacy: when it happens to you
In this first part of a three-part series on cyber preparedness, Dr. Colleen Malashock, Clinical Pharmacy Manager at Nebraska Medicine, and Randy Gerwitz, Senior Consulting Director in Pharmacy Solutions at Vizient, share their firsthand insights on the impact of cyberattacks to health care facilities and the preparations necessary to providing pharmacy services and managing patient care during the downtime.   Guest speakers: Colleen Malashock, PharmD, BCPS, DPLA Clinical Pharmacy Manager  Nebraska Medicine   Randy Gerwitz, RPh Senior Consulting Director in Pharmacy Solutions  Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:59-3:24] Colleen’s experience with cyber attack [03:25-4:00] Advance preparations [04:01-5:18] Most effective approaches during and after event [05:19-6:07] What surprised them most about the event [6:08-6:43] How did clinical services fare [6:44-7:46] How prepared are systems for this kind of intrusion [7:47-9:45] Impact on pharmacy staff  [9:46-11:52] Advice for pharmacy and frontline staff [11:53-13:41] Transitioning to a paper system   Links | Resources: "Clinicians' experiences and reflections from a health system cyber attack." Click here Ransomware attacks on hospitals 2022 Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
What’s pneu with pneumococcal vaccines?
Mar 29 2022
What’s pneu with pneumococcal vaccines?
John Schoen, Senior Clinical Manager of Drug Information, at Vizient, shares his insights on the history and current state of pneumococcal vaccines within the practitioner community. He also discusses the complexity of ACIP recommendations after the recent addition of two newer vaccines, PCV 20 and PCV 15, and what the future holds for the vaccines.   Guest speaker: John Schoen, PharmD, BCPS Senior Clinical Manager of Drug Information  Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:51-1:51] John’s background [01:52-4:22] Pneumococcal vaccines history and current [04:23-7:30] Significance of vaccines [07:31-9:33] What’s new with Pneumococcal vaccines [09:34-12:00] How expanded serotype coverage changes things [12:01-15:37] Efficacy data points from recent studies [15:38-16:26] Safety concerns from trials [16:27-18:51] Current ACIP recommendations [18:52-23:10] How to deal with the different combinations of vaccines [23:11-24:37] Safety implications of vaccine combinations [24:38-25:43] How frontline staff positions itself for appropriate support [25:44-27:50] What to expect for the future of pneumococcal immunizations   Links | Resources: Side-by-side comparison for the pneumococcal vaccines Public access link: Click Here Member only (comprehensive) link: Click Here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
EBM’s anatomy: what’s the differential diagnosis mid-pandemic?
Mar 8 2022
EBM’s anatomy: what’s the differential diagnosis mid-pandemic?
Stacy Lauderdale, Senior Director of Drug Information, and Kyle Hoelting, Senior Manager of Drug Information at Vizient, share their insights on the history and current state of evidence-based medicine within the practitioner community. They also discuss how to reverse the trend of using anecdotal experience and swing the pendulum back to increased reliance on evidenced based medicine.   Guest speakers: Stacy Lauderdale, PharmD, BCPS Senior Director of Drug Information  Vizient   Kyle Hoelting, PharmD, BCPS Senior Manager of Drug Information  Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:55-2:18] Kyle and Stacy’s backgrounds [02:19-3:45] Evidence Based Medicine definition and history [03:46-5:54] Current state of EBM [05:55-10:45] Basic tools of EBM [10:46-14:29] Difference between clinical and statistical significance [14:30-15:56] Outcomes   [15:57-18:28] Role of FDA in promoting EBM [18:29-20:27] How pharmacy and therapeutics committees incorporate EBM [20:28-21:15] EBM Resources   Links | Resources: Seigfried RJ, Corbo T, Saltzberg MT, Reitz J, Bennett DA. Deciding which drugs get onto the formulary: a value-based approach Value Health. 2013 Jul-Aug;16(5):901-6.   Riegelman RK, Nelson BA. Studying a Study & Testing a Test: Reading Evidence-Based Health Research. Philadelphia: Wolters Kluwer; 2021.   Gehlbach SH. Interpreting the Medical Literature. 5th ed. New York: McGraw Hill; 2006.   Malone PM, Malone MJ, Park SK. Drug information: a guide for pharmacists. 6th ed. New York:  McGraw Hill; 2014.   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Practical tips for publishing
Feb 8 2022
Practical tips for publishing
Paul Szumita, Clinical Pharmacy Director at Brigham and Women's Hospital, shares how to participate in publishing research by working to fill gaps in the literature. Paul discusses with host Gretchen Brummel different types of publications that pharmacists get involved, some past projects of his own, training you need to publish, and how to get started in publishing work.   Guest speaker: Paul Szumita, PharmD, FCCM, FASHP, BCCCP, BCPS    Director, Clinical Pharmacy Services Brigham and Women's Hospital   Moderator: Gretchen Brummel, PharmD, BCPS   Director, Clinical Pharmacy Services Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:47-2:10] Paul’s background and current position [02:11-2:47] Number one piece of advice to start publishing [02:48-4:42] Fitting publishing into day-to-day work [04:43-5:56] Different publications to get you involved [05:57-7:05] Paul’s own projects [07:06-9:08] Barriers to publishing [09:09-10:04] Training needed [10:05-12:59] Process of submitting [13:00-14:41] Small scale ways to get started [14:42-18:43] Advantages to solo and team publishing [18:44-20:23] Future of pharmacy-based publication   Links | Resources: How-to guide for overcoming barriers of research and scholarship training in Pharm.D. and pharmacy residency programs Click here Residency research training: Need to rethink the prescription for success? Click here Barriers to publishing in biomedical journals perceived by a sample of French researchers: results of the DIAzePAM Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Information overload: tips and tricks for staying on top of the literature, part 2
Jan 18 2022
Information overload: tips and tricks for staying on top of the literature, part 2
Sara J. Hyland, Clinical Pharmacist at OhioHealth Grant Medical Center, returns in Part 2 to share tools, expertise and strategies on how to stay ahead of the overwhelming volume of contributions to in this information age. Sara discusses with host Gretchen Brummel how to develop a multi-pronged system for limiting the workload of keeping up, skimming and drilling strategies and maintaining your system so it stays current.   Guest speaker: Sara J. Hyland, PharmD, BCCCP Clinical Pharmacist  OhioHealth Grant Medical Center   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:41-3:25] Ways to limit the workload associated with staying current [03:26-11:26] Skimming and drilling strategies [11:26-13:42] Maintaining your system   Links | Resources: Haines Answer final - ACCP: Click here How to keep up to date with medical information using web-based resources: a systematised review and narrative synthesis Click here Keeping Up With the Medical Literature: Why, How, and When? | Stroke Click here Staying Up to Date and Managing Information Overload Click here Keeping Up with the Medical Literature: How to Set Up a System - American Family Physician - American Academy of Family Physicians Click here Learn Like a Pro: Barbara Oakley, PhD: 9781250799371: Amazon.com: Books Click here #50: How to read the medical literature like a journal editor - The Curbsiders Click here Evidence-Based Strategies to Better Remember What You Learn - learntrepreneurs Click here Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? - PubMed Click here Scientific literature: Information overload | Nature Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Information overload: tips and tricks for staying on top of the literature, part 1
Jan 11 2022
Information overload: tips and tricks for staying on top of the literature, part 1
Sara J. Hyland, Clinical Pharmacist at OhioHealth Grant Medical Center, shares tools, expertise and strategies on how to stay ahead of the overwhelming volume of contributions to in this information age. Sara discusses with host Gretchen Brummel how to develop a multi-pronged system for identifying relevant literature to your practice, automating, and organizing that literature and balancing reading with work and personal time.   Guest speaker: Sara J. Hyland, PharmD, BCCCP Clinical Pharmacist  OhioHealth Grant Medical Center   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:47-1:43] Sara’s background and current practice [01:43-3:10] Problem in keeping up with medical literature [03:10-4:05] Where do you start? [04:06-7:40] Tools Sara uses for keeping up [07:41-10:39] Leveraging other professionals   Links | Resources: How to keep up to date with medical information using web-based resources: a systematised review and narrative synthesis Click here Keeping Up With the Medical Literature: Why, How, and When? | Stroke Click here Staying Up to Date and Managing Information Overload Click here Keeping Up with the Medical Literature: How to Set Up a System - American Family Physician - American Academy of Family Physicians Click here Learn Like a Pro: Barbara Oakley, PhD: 9781250799371: Amazon.com: Books Click here #50: How to read the medical literature like a journal editor - The Curbsiders Click here Evidence-Based Strategies to Better Remember What You Learn - learntrepreneurs Click here Seventy-five trials and eleven systematic reviews a day: how will we ever keep up? - PubMed Click here Scientific literature: Information overload | Nature Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Getting to the heart of the matter: insights from a new infective endocarditis prevention statement
Dec 14 2021
Getting to the heart of the matter: insights from a new infective endocarditis prevention statement
Dr. Jason Goodchild, Vice President of Clinical Affairs at Premier Dental Products Company, and Dr. Mark Donaldson, Associate Principal in Pharmacy Advisory Solutions at Vizient discuss the merits of a recent statement on antibiotic prophylaxis for infective endocarditis with host Gretchen Brummel.   Guest speakers: Jason Goodchild, DMD Vice President of Clinical Affairs Premier Dental Products Company   Mark Donaldson, BSP, ACPR, PHARMD, FASHP, FACHE Associate Principal, Pharmacy Advisory Solutions Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [00:53-1:55] Antibiotic prophylaxis against infective endocarditis as an important tool [01:56-2:48] Risks of over- or underutilization of this treatment modality [02:49-4:52] History of the guidelines [04:53-5:48] New statement impacts moving forward [05:49-8:49] Doxycycline as alternative to clindamycin in penicillin-allergic patients [08:50-9:47] The rationale to abandon clindamycin [09:48-11:49] How clindamycin compares to other agents [11:50-12:59] The bottom line   Links | Resources: Prevention of Viridans group Streptococcal infective endocarditis: a scientific statement from the American Heart Association: Click here Prevention of infective endocarditis: guidelines from the American Heart Association: Click here Antibiotic prophylaxis guidelines: is there new information for 2021? Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Vizient Pharmacy Vision Awards: success story in innovation
Dec 7 2021
Vizient Pharmacy Vision Awards: success story in innovation
Megan LaBreck, Antiarrhythmic Clinic Pharmacist at OhioHealth and winner of the Vizient Pharmacy Vision Award for Excellence in Innovation, discusses her program that transfers the management of nearly 1,400 patients on an antiarrhythmic drug and their monitoring from the exclusive management of a physician to a pharmacist-led service with host Gretchen Brummel.   Guest speakers: Megan LaBreck, PharmD, BCPS, CACP Antiarrhythmic Pharmacist OhioHealth   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [01:00-2:30] Transferring the management of nearly 1,400 patients on antiarrhythmic drugs and monitoring from a physician to a pharmacist-led service [02:32-4:05] Solving the problem from the pharmacy point of view [04:06-5:00] Identifying complexities and fixing issues [05:01-6:06] Where did the idea come from for this program [06:07-6:49] Designing the collaborative practice agreement     [06:50-7:41] Training necessary to offer these services [07:42-10:09] Discovering other opportunities [10:10-11:53] Impact of shifting this activity to an outpatient setting [11:55-13:01] How the program influenced patient satisfaction [13:02-14:03] Future plans [14:04-15:38] Advice for new practitioners or frontline staff   Links | Resources: 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Click here Comparison of QT Interval Readings in Normal Sinus Rhythm Between a Smartphone Heart Monitor and a 12-Lead ECG for Healthy Volunteers and Inpatients Receiving Sotalol or Dofetilide: Click here 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: Click here Vizient Pharmacy Vision Awards: Excellence in Innovation: Click here Vizient Pharmacy Vision Awards: Click here   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
When your cup is empty: secondary traumatic stress in pharmacy practice
Nov 9 2021
When your cup is empty: secondary traumatic stress in pharmacy practice
The pressures and stress of traumatic clinical events affects everyone in the room including pharmacists. Two pharmacists, Jennifer Mando-Vandrick, Clinical Pharmacist in Emergency Medicine at Duke University Hospital and Philippe Mentler, Consulting Director of Pharmacy at Vizient, discuss the emotional impact pharmacist may have when witnessing the distress of others when traumatic events happen in the clinical workplace.    Guest speakers: Jennifer Mando-Vandrick, PharmD, BCPS Clinical Pharmacist, Emergency Medicine Director, PGY2 Emergency Medicine Residency Department of Pharmacy Duke University Hospital   Philippe Mentler, PharmD, BCPS Consulting Director, Pharmacy Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [3:31] Secondary traumatic stress or compassion fatigue is a state of emotional distress that results from indirect exposure to traumatic events [4:00] How secondary traumatic stress differs from burnout [6:15] How to manage your stress level [9:23] Acknowledge  and accept that you are feeling stress and be open to listening to other people’s feelings [9:50] How leadership can help their employees deal with stress [12:00] Peer support [13:07] Talking to your learners and applicants about how your organization’s culture manages employee stress   Links | Resources: CDC: Mental Health articles Psychology Today   Subscribe Today! Apple Podcasts Amazon Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
A periop love story: sugamma-next? Or stay with your (neo) ex?
Oct 12 2021
A periop love story: sugamma-next? Or stay with your (neo) ex?
The debate on whether to use sugammadex or neostigmine has heated up dramatically in recent years. Two industry experts, Eric Johnson, perioperative critical care pharmacist at UK HealthCare, and Stacy Lauderdale, senior director for drug information at Vizient, discuss the many considerations involved in choosing between the two agents.   Guest speakers: Eric Johnson, PharmD, BCCCP Perioperative Critical Care Pharmacist UK HealthCare   Stacy Lauderdale, PharmD, BCPS Senior Director, Drug Information Vizient   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [01:11] Neuromuscular blockers play two main roles in the perioperative setting.  [01:52] The ability to reverse neuromuscular blockade is important for prevention or decreased incidence of adverse effects.    [03:07] In 2013, neostigmine received FDA approval, eliminating all other non-FDA-approved versions from the market. [03:32] The sole supplier of neostigmine raised the cost ~450%. [03:52] In 2015, sugammadex received FDA approval and hit the market at a cost similar to neostigmine. [04:13] Neostigmine’s cost has dropped since 2015, causing member hospitals to question the added value of sugammadex. [04:37] One institutional use was 90% sugammadex vs. 10% neostigmine.     [05:07] Via Pharmacy Market Outlook, Vizient has found that sugammadex is the number-three top-spend drug in the acute care setting. [06:01] One benefit of sugammadex is its ability to reverse at a deeper level. [06:24] Another benefit of sugammadex is its lack of cardiovascular effects. [06:55] Sugammadex displays more optimal pharmacokinetics. [07:58] Important safety and quality factors to consider. [08:53] Studies cannot conclusively determine if sugammadex reduces postoperative respiratory complications. [09:10] The cost difference between sugammadex and neostigmine continues to grow. [09:50] Vizient assembled an expert panel of 12 multidisciplinary specialists to review the comparative effectiveness of sugammadex vs. neostigmine. [10:32] The focus of the panel was to look at outcomes that have a measurable impact on patient quality, safety and cost. [11:45] The panel used the Institute for Clinical and Economic Review Matrix to rate the comparative effectiveness of sugammadex and neostigmine. [12:21] The ICER Matrix assisted the panel in determining the magnitude of difference between the two therapies.  [14:46] Anesthesiologists’ concern about the lack of resident training with neostigmine [15:39] Final report, that will include many more findings, to be published in the fourth quarter of 2021. [16:08] Importance of train-of-four monitoring   Links | Resources: National Library of Medicine, “Sugammadex versus Neostigmine for Reversal of Neuromuscular Blockade and Postoperative Pulmonary Complications (STRONGER): A Multicenter Matched Cohort Analysis,” Anesthesiology, 2020 June 1 Click here National Library of Medicine, “Postoperative Pulmonary Complications' Association with Sugammadex versus Neostigmine: A Retrospective Registry Analysis,” Anesthesiology, 2021 June 1 Click here   Subscribe Today! Apple Podcasts Google Podcasts Spotify Stitcher Android RSS Feed
Enhanced Recovery After Colorectal Surgery
Sep 14 2021
Enhanced Recovery After Colorectal Surgery
Historically there have been countless paths to recovery following colorectal surgery. However, having a well-rounded, evidence-based enhanced recovery program is critical to patient success. Two Vizient experts, Mark Ninno and Karen Smethers discuss the details and the power of these programs.    Guest speakers: Mark Ninno, PharmD Senior Consulting Solutions Director Vizient   Karen Smethers, PharmD, BCOP MSS Pharmacy Network Senior Director Vizient Pharmacy Member Services   Moderator: Gretchen Brummel, PharmD, BCPS Pharmacy Executive Director Vizient Center for Pharmacy Practice Excellence   Show Notes: [01:21] Enhanced recovery programs are specific programs designed to help patients after surgery [01:59] Strong recovery programs involve four pillars to achieve its goal of patient discharge: patient-centered, multi-modal, multidisciplinary and evidence-based approaches [03:29] Vizient observes that health systems have a wide variety of practices following colorectal surgery [03:56] Vizient gathered a panel of experts to assess and evaluate recovery programs [04:16] The expert panel focused on two specific domains: literature review and expert opinion     [05:33] Vizient evidence review includes pharmacological and non-pharmacological interventions [06:09] Early introduction of oral feeding proved to have the strongest support in recovery [06:24] Studies involving alvimopan contain many factors that hinders its application in an enhanced recovery program [07:10] Vizient found many systems are supporting alvimopan use in minimally invasive surgery even though the evidence may not fully support this practice [07:46] Non-drug regiments such as chewing gum and caffeine have been handed down for many years, yet these therapies have minimal benefits [08:33] It’s critical for front line pharmacists to collaborate with all health care professionals [08:59] Education of prescribers, patients and family members provide many benefits   Links | Resources: American Association of Nurse Anesthesiology (AANA): Enhanced Recovery after Surgery Click here Scott MJ, Baldini G, Fearon KCH, et al. Enhanced Recovery After Surgery (ERAS®) for gastrointestinal surgery, part 1: pathophysiological considerations. Act Anaesthesiol Scand. 201559(10):1212-1231 Click here Gustafsson UO, Scott MJ, Hubner M, Et al, Guidelines for perioperative care in elective colorectal surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations: 2018. World J Surg. 2019 ;43(3):659-695 Click here   Subscribe Today! Apple Podcasts Google Podcasts Spotify Stitcher Android RSS Feed