BENCH to BEDSIDE

Dr. Susan Furth

Susan Furth, MD, PhD, chief scientific officer of Children’s Hospital of Philadelphia Research Institute, showcases the ingenuity of scientists and staff who make achievements in pediatric science possible. read less
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New Frontiers: Precision Medicine a ‘Unique Signature’ for Pediatric Cancer Patients
Mar 8 2024
New Frontiers: Precision Medicine a ‘Unique Signature’ for Pediatric Cancer Patients
Precision medicine, also known as personalized medicine, has revolutionized how physicians and scientists treat and study disease. According to Theodore Laetsch, MD, an oncologist at Children’s Hospital of Philadelphia, this ability to track and tailor individual patients’ unique genetic signatures has the most transformative potential in pediatric cancer. In this episode of Bench to Bedside, Dr. Laetsch shares how his new Frontier Program, the Center for Precision Medicine for High-risk Pediatric Cancer, harnesses advanced technologies and a growing multi omics database to optimize outcomes for childhood cancer patients.

Episodes

New Frontiers: Precision Medicine a ‘Unique Signature’ for Pediatric Cancer Patients
Mar 8 2024
New Frontiers: Precision Medicine a ‘Unique Signature’ for Pediatric Cancer Patients
Precision medicine, also known as personalized medicine, has revolutionized how physicians and scientists treat and study disease. According to Theodore Laetsch, MD, an oncologist at Children’s Hospital of Philadelphia, this ability to track and tailor individual patients’ unique genetic signatures has the most transformative potential in pediatric cancer. In this episode of Bench to Bedside, Dr. Laetsch shares how his new Frontier Program, the Center for Precision Medicine for High-risk Pediatric Cancer, harnesses advanced technologies and a growing multi omics database to optimize outcomes for childhood cancer patients.
New Frontiers: Talking Heart-to-Heart About Pediatric Heart Failure
Feb 9 2024
New Frontiers: Talking Heart-to-Heart About Pediatric Heart Failure
From pathology to prognosis, heart failure in children appears vastly different than it does in adults. How we study, approach, and ultimately treat the disease should too, according to Joseph Rossano, MD, chief of the Division of Cardiology at CHOP. As director of the Advanced Cardiac Therapies for Heart Failure Patients Frontier Program, Dr. Rossano aims to bring cutting-edge scientific discoveries from the bench to the bedside with this in mind.
New Frontiers: At the Forefront of Hemophilia Treatment With CHOP
Jan 12 2024
New Frontiers: At the Forefront of Hemophilia Treatment With CHOP
With a stroll down the hallway at Children’s Hospital of Philadelphia, you run into a tremendous knowledge base and expertise to help answer challenging scientific questions in pediatrics. Lindsey George, MD, PhD, director of the Novel Therapeutics for Bleeding Disorders Frontier Program, shares how this combined clinical experience in gene therapy for hemophilia and in other related bleeding disorders leads toward innovative approaches.
New Frontiers: CHOP Neonatologists Develop the Delivery Room of the Future
Dec 8 2023
New Frontiers: CHOP Neonatologists Develop the Delivery Room of the Future
Since establishing the first surgical intensive care unit (ICU) for newborns and infants in 1962, Children’s Hospital of Philadelphia has been at the forefront of transforming care for its tiniest patients. The Delivery Room of the Future Frontier Program, directed by neonatologist Elizabeth Foglia, MD, aims to provide every infant a chance at the healthiest outcomes and quality of life.
100 Years of Research: Driven to Prevent Injury in Children
Oct 3 2023
100 Years of Research: Driven to Prevent Injury in Children
“Be bold. Solve important problems,” shares Bench to Bedside guest, Flaura Winston, MD, PhD, founder and co-scientific director of the Center for Injury Research and Prevention. Hear how this Center of Emphasis takes a research action to impact approach when it comes to preventing injury in children.
100 Years of Research: Bringing ‘Amazingly Creative Ideas’ to Discover New Gene and Cell Therapies
May 5 2023
100 Years of Research: Bringing ‘Amazingly Creative Ideas’ to Discover New Gene and Cell Therapies
Dr. Beverly Davidson and her multidisciplinary team at the Raymond G. Perelman Center for Cellular and Molecular Therapeutics are working on “aha moments,” both big and small, to improve gene and cell therapies in search of cures for debilitating disorders.
Center for Applied Genomics: Translating Basic Research Findings Into Medical Innovations
Mar 20 2023
Center for Applied Genomics: Translating Basic Research Findings Into Medical Innovations
Join the conversation with Hakon Hakonarson, MD, PhD, founding director of the Center for Applied Genomics, where scientists develop new and better ways to diagnose and treat children affected by rare and complex medical disorders.
100 Years of Research: Solutions-oriented Health Equity Research
Jan 27 2023
100 Years of Research: Solutions-oriented Health Equity Research
Dr. Diana Montoya-Williams wants her advocacy-informed research to matter to the communities she is trying to help. She's an attending neonatologist and faculty member of PolicyLab at CHOP whose research covers health disparities, social determinants of health, perinatal health policy, and immigration policies.
100 Years of Research: Building an Environment Where People Want to Be
Dec 16 2022
100 Years of Research: Building an Environment Where People Want to Be
Paulette McRae, PhD, Associate Director of Specialty Programs and Diversity in the Office of Academic Training and Outreach Programs, has devoted her career to Diversity, Equity, and Inclusion initiatives that open doors for the next generation, so that they can see how they can make a difference in research.
100 Years of Research: Health Equity is Everybody’s Work
Nov 21 2022
100 Years of Research: Health Equity is Everybody’s Work
The Center for Health Equity at CHOP aims to address social disease and provide unbiased clinical care so that children in Philadelphia and beyond can achieve their best health. The Center's Director Tyra Bryant-Stephens, nationally recognized for her work in community-driven, evidence-based research in asthma interventions, shares why "health equity is a state of mind.
100 Years of Research: Pursuit of Discovery ’Built In’ From Very Beginning
Oct 14 2022
100 Years of Research: Pursuit of Discovery ’Built In’ From Very Beginning
Seeing discoveries happen is "one of the most invigorating and exciting parts of my job," shares Bench to Bedside guest, Madeline Bell, Children's Hospital of Philadelphia President and Chief Executive Officer. Hear how research touches every part of CHOP, and the ways we're continuing our legacy of 100 years of trailblazing research.
100 Years of Research: Insights Into Evolution of Vaccine Development
Sep 9 2022
100 Years of Research: Insights Into Evolution of Vaccine Development
Much like the scientist who led the first research lab at CHOP in 1922, our Bench to Bedside guest, Dr. Paul Offit, director of the Vaccine Education Center, has spent most of his career studying infectious diseases with a focus on vaccine development. He gives us a look back at how vaccine development has evolved and shares "the most fun time of his life" as a scientist.
100 Years of Research: From the Basement to a Bird’s Eye View
Aug 5 2022
100 Years of Research: From the Basement to a Bird’s Eye View
We’re celebrating the 100th anniversary of the first research lab at Children’s Hospital of Philadelphia! Our Bench to Bedside guest hasn’t been a CHOP employee for quite *that* long, but he has dedicated three-and-a-half decades of his career here. Meet Howard Eck, director of Research Resources, who knows every corner of the Research Institute and sets our scientists’ laboratories up for success.