X-Health.show - meet the future of healthcare

Alex Jani: interviewing visionaries of healthcare innovation

The X-Health.show brings to you brilliant minds behind programming living cells, tech that detects pre-term delivery in seconds, brain-computer interface or apps that employ AI to match you, your disease with the best treatment.

For the eXtra Health of the future.

You’ll meet visionaries from Switzerland who push the boundaries of healthcare.

Engineers who teamed up with doctors, scientists turned CEOs, doctors programming AI-powered apps, researchers who abandoned university labs to improve your health.

You’ll hear stories of promising startups founders and successful serial entrepreneurs.

Patients who imagine a better way.

You’ll
learn about new disease treatments
understand how AI-driven health tech can improve your life
grasp the way founders innovate
or even, get inspired to jumpstart innovation at your company.

Luckily, the X-Health.show is based in Switzerland, the most innovative country in the world according to World Intellectual Property Organization. For the 12th consecutive year. No wonder when the abundance of funds for innovation meets the ability to commercialize the discoveries.

With notable research institutions situated nearby top pharmaceutical companies, there’s more to expect. More medical innovations, break-through femtech, life changing biotech, developments in digital health, genetic engineering, and  wearables, such as smart ring, blood pressure measurement on your wrist or ECG in your pyjama.


Follow the show to meet these amazing innovators.

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Health & FitnessHealth & Fitness

Episodes

Breast Shell for Radiotherapy in Breast Cancer: Giovanna Dipasquale, HeroSupport
Dec 10 2024
Breast Shell for Radiotherapy in Breast Cancer: Giovanna Dipasquale, HeroSupport
Currently: patients with breast cancer are adjusted to fit a table for radiotherapy.Soon: the table will be fitted to them.A personalized shell, 3D-printed for one specific patient, will be used for all radiation sessions.Less pain.More comfort.Shorter radiation sessions.In this episode, you will hear aboutthe benefits of radiotherapy in breast cancerradiotherapy for breast cancer side effectsand how clinical practice and a personal story motivate the founders EVERY DAYMy guest, Giovanna Dipasquale, is a co-founder and CEO of HeroSupport. A medical physicist with over two decades of experience in radiotherapy at one of the biggest hospitals in Europe, the Geneva University Hospital, where she led a study in 3D printing for radiotherapy.HeroSupport is a Swiss startup that is developing a personalized breast shell for radiotherapy in cancer treatment. Venus Shell allows for shorter radiation sessions, more comfort, and more precision.Follow them athttps://www.herosupport.care/ Please note: the shell is not yet available for patients but clinics may sign up for clinical trials. If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Developing a Blood Test for Breast Cancer: Dr. Ivana Domljanovic, Xemperia
Nov 28 2024
Developing a Blood Test for Breast Cancer: Dr. Ivana Domljanovic, Xemperia
The goal is to have a breast cancer test at a point of care, say—at your family doctor’s office.And regularly.In this episode, you will hear aboutDNA origami and DNA as a building materialthe role of microRNAsand how a love for basketball led to becoming a DNA scientistMy guest, Dr. Ivana Domljanovic, is a postdoctoral researcher at the University of Fribourg and a scientist at Xemperia. She was awarded the Swiss Nanotechnology PhD Award for the invention of novel patented DNA origami biosensor.Xemperia is a Swiss startup, headed by Prof. Ruegg Curzio, on a mission to reduce breast cancer mortality by detecting and addressing cancer at its earliest stage. Ivana works there on developing a rapid blood test for breast cancer detection and the early detection of relapses.Go ahead and follow what they do athttps://xemperia.com/ If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Free Medication Reminders App: Dr. Redona Hafizi, TOM Medications
Nov 19 2024
Free Medication Reminders App: Dr. Redona Hafizi, TOM Medications
No email, no name, not even a login is required when signing up. You just start using the app so you don’t forget to take your meds.Wait, what?In this episode, you’ll hear about:a free medication reminders appwhy people don’t adhere to therapieshow patients control what they share and even earn moneyand how pharmaceutical and insurance companies can listen better to patients and support them with real-world data in cardiovascular, alimentary tract, metabolic diseases such as diabetes, nervous system conditions such as depression, and moreMy guest, Dr. Redona Hafizi is a co-founder and Head of Pharma at TOM Medications. With a PhD in industrial pharmaceutical science, she’s an expert in pharmaceutical insights. And guess what, they’re absolutely fascinating. TOM Medications is a Swiss startup that developed an app – for patients and with patients–to remind them to take their medications. The app is free. And already now, there’s a plethora of real-time patient data, valuable to pharmaceutical and insurance companies.Here’s when you can learn more about TOM:https://www.tommedications.com/Timestamps:00:00:00 Dr. Redona Hafizi and TOM Medications00:01:14 The Actual Profits of Using the App00:02:28 Setting Up the Medication Reminder App00:13:41 What Medication Adherence Means00:27:03 Iterating and Growing the App by Listening to Users00:32:27 Helping Pharma Be More Patient-Centric: Real-World Data, But Faster00:41:52 Checking for Double Medication with Insurance Companies00:47:20 Scaling Up to Make the Healthcare System More Patient-Centric00:50:58 Thank You, Follow TOM Medications00:52:08 Follow the X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
New Antioxidant Supplement for Brain Longevity: Prof. Roland Martin, Noubrain
Nov 12 2024
New Antioxidant Supplement for Brain Longevity: Prof. Roland Martin, Noubrain
It is absolutely fascinating what impact such a simple, naturally occurring compound can have.An antioxidant that is 20-30 times more potent than vitamins C and E.And has the potential to protect brain longevity, including in cases of Multiple Sclerosis, Alzheimer’s Disease, Parkinson’s disease, after stroke, depression, spinal cord injury.In this episode you’ll hear abouthow the brain ages and when this process beginswhat are free radicalshow hydroxytyrosol, a natural neuroprotectant, workspre-clinical research in models for brain and spinal cord trauma, depression, Alzheimer's disease, Parkinson's diseaseMy guest, Prof. Roland Martin, is a co-founder of Noubrain and Cellerys. A world-class neurologist, specializing in neuroimmunology, renowned for his research into multiple sclerosis. His whole career working in academic institutions close to patients, in the US, Germany, Spain, and Switzerland.Noubrain is a Swiss startup that has developed neuroprotective supplements with hydroxytyrosol, a powerful antioxidant derived from olives and olive leaves. They have some promising unpublished pre-clinical results related to multiple sclerosis.Go ahead and follow what they do athttps://www.noubrain.ch/ – in German but you know what to do, hit that translate button in your browser ;-)Timestamps:00:00:00 Prof. Roland Martin and Noubrain00:01:18 Brain Aging00:08:08 What Are Free Radicals?00:12:40 Screening Compounds of the Mediterranean Diet00:15:50 What Is Hydroxytyrosol?00:25:29 Strong Antioxidant Supplement That Enters the Brain00:34:59 Research Behind Hydroxytyrosol00:46:35 New Antioxidant Availability00:51:51 Thank You Follow Noubrain00:52:40 Follow X-Health.show Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Off-the-Shelf “Human” Tissue for Reconstructing Urethra Narrowing: Dr. Eva-Maria Balet, Regenosca
Nov 5 2024
Off-the-Shelf “Human” Tissue for Reconstructing Urethra Narrowing: Dr. Eva-Maria Balet, Regenosca
It is not human tissue, i.e., it doesn’t come from a humanbut it is recognized by the body and well-tolerated.In effect, patients undergoing urethral stricture reconstruction have better recovery and less pain.In this episode, you will hear aboutregenerative medicineurethral stricture symptomsa scaffold that attracts the patients’ own cells surrounding the removed tissue and stimulates regenerationhow it dissolves itself, when the job is doneMy guest, Dr. Eva-Maria Balet, is a co-founder and CEO of Regenosca. She’s a biotechnologist with a PhD in Life Sciences from EPFL, a public research university in Lausanne. She has focused her research on scaffold design.Regenosca is a Swiss startup developing TissueSpan mesh – a technology platform to create regenerative, off-the-shelf meshes for soft tissue repair. Their first indication is urethral stricture – first-in-human implantations show shorter surgery time and less pain for patients.Here’s more about them,https://www.regenosca.com/Timestamps:00:00:00 Dr. Eva-Maria Balet and Regenosca00:01:18 Bridge That Helps Tissue Healing00:02:49 Innovation Behind the Scenes00:05:03 Urethra Reconstruction: Gold Standard00:07:05 What Is Urethral Stricture00:12:50 Collagen-Based Scaffold for Urethra Narrowing Reconstruction00:16:34 How Does TissueSpan Mesh Work00:22:18 First-In-Men Studies in Malaysia00:31:32 Planning the Startup Growth00:44:35 Thank You, Follow Regenosca00:45:05 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Turn Your Traditional Watch into a Health Tracker – Smart Strap for Longevity: Olga Nijpels-Tishurova, Watchibia
Oct 22 2024
Turn Your Traditional Watch into a Health Tracker – Smart Strap for Longevity: Olga Nijpels-Tishurova, Watchibia
How does your health tracker fit into your style?Well, my guest today wasn’t happy with how her plastic-looking health tracker did not match her Rolex. But longevity was important to her. Connecting the dots, she started developing a smart strap. To her Rolex. Or Omega, Gucci, Patek Philippe – any traditional watch you fancy.In this episode, you will hear abouta health tracker that matches your stylehigh-end vulcanized rubber used for this smart strapwhat you can track with a smart strap health trackera startup collaboration with CSEM or Swiss Center for Electronics and Microtechnologyand how a smart strap can save the traditional watch industryMy guest, Olga Nijpels-Tishurova, is the founder and CEO of Watchibia. She’s combined her experience in the electronics industry with her love for luxury watches and aesthetics, and a focus on extending healthspan.Watchibia is a Swiss startup that develops a smart strap for traditional watches. Think, wearing your favorite watch, a Rolex, Omega, Gucci, Patek Philippe, whatever you fancy, and simply changing the strap to track your health. No additional fitness tracker needed.Go ahead and follow Watchibia on Instagram https://www.instagram.com/watch_ibia/ and Olga on LinkedIn: https://www.linkedin.com/in/olga-nijpels-tishurova-b211a219/Timestamps:00:00:00 Olga Nijpels-Tishurova and Watchibia00:01:22 Why Olga Dropped a Plastic Health Tracker00:05:09 The Idea for a Smart Strap for a Rolex00:11:43 What Is the Smart Strap00:19:27 Developing the Smart Strap for Longevity00:25:40 Saving the Traditional Watch Industry00:37:55 Thank You Follow Watchibia00:38:43 Follow X-Health.show Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Isolating Extracellular Vesicles and the Future of Nanomedicine: Dr. Adva Krivitsky, Acytronix
Oct 16 2024
Isolating Extracellular Vesicles and the Future of Nanomedicine: Dr. Adva Krivitsky, Acytronix
Will we, in the future, be detecting diseases using extracellular vesicles?Will these diagnostics replace MRI or CT?In this episode, you’ll hear aboutthe personalized medicine of the futurewhat is nanomedicinehow to isolate pure extracellular vesicleswhat are extracellular vesicles and how they compare to stem cell treatmentsMy guest today, Dr. Adva Krivitsky, is a co-founder and the CEO of Acytronix. She’s both a biologist and a chemist by training and completed her PhD in nanomedicine: polymer therapeutics, RNA delivery, and cancer research.Acytronix is a Swiss startup that developed a portable microstructured electrochemical device to isolate extracellular vesicles in less than 10 minutes. These extracellular vesicles can be key in detecting and treating diseases–more gently–in the future.Here’s more about Acytronix:acytronix.ch If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
How to Break a Phone Addiction with This Screen Time App: Ondrej Zak, Zario
Oct 8 2024
How to Break a Phone Addiction with This Screen Time App: Ondrej Zak, Zario
Take a wild guess: how many years will you get back when you limit your screen time?Yes, I said: YEARS.Spoiler: more than you think. But my guest gives an exact number.Because in this episode, you’ll hear abouta phone addiction – or “problematic phone use” if you preferhow to tell if you’re addicted to your phonehow to break a phone addictionand how a screen time app can helpMy guest, Ondrej Zak is the CEO of Zario. He’s got a solid background in advising on digital transformation, new business models, and creating digital products.Zario is a Swiss startup that developed an app to help us regain control over our digital habits. Think: screen time, scrolling – you get the idea. It uses behavioral psychology and gamifies experience to promote sustainable habit change. Already available in both the App Store and Google Play Store check them there or go to their website:https://www.meetzario.com/Timestamps:0:00 Ondrej Zak and Zario1:19 Tinder Match at a C-Level Meeting3:53 Cheating on Self-Imposed Phone Restrictions6:12 Average Screen Time13:59 How to Check Screen Time On iPhone, How to Check Screen Time on Android17:45 Testing the Zario Screen Time App23:58 How to Know if I Am Addicted to My Phone32:19 Use Social Media Methods to Make You Unhooked38:25 Zario Team, London School of Economics and Lucerne University46:29 Thank You, Follow Zario46:58 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Science-Backed Weight Loss With No Yo-Yo Effect: Dr. Julia Vogel Wenzin, LEALY
Oct 1 2024
Science-Backed Weight Loss With No Yo-Yo Effect: Dr. Julia Vogel Wenzin, LEALY
80% of people who lost weight, kept that weight off after two years.But quite a few did not even start.Those who did, did not follow any particular diet.People are too individual to follow one diet.They did not count calories.People hate counting calories.They love healthspan.They love longevity.What science-backed solutions work?In this episode you will hear about4 simple rules you will want to follow to lose weightwhy most people would NOT follow on themhow one of the co-founders lost 40 kilosand how LEALY achieved an 80% success rateMy guest, Dr. Julia Vogel Wenzin is a co-founder and the CEO of Lealy. She holds a Ph.D. in Computer Science, Computer Vision, and Machine Learning and has a track record of designing digital solutions.Lealy is a Swiss startup that helps overweight people lose weight. Not by offering any miraculous diet. With the origins at a Swiss private clinic, they now offer in their app a blended care habit change program. Currently available in Switzerland.Check out their website in Germanhttps://www.lealy.health/Timestamps00:00:00 Julia Vogel Wenzin and LEALY00:01:09 Two Years to Lose Weight00:02:40 What Is Overweight00:05:55 40 Kg Permanent Weight Loss00:14:06 Blended Weight Loss Program With No Yo-Yo Effect00:20:30 Why More Women Than Men Seek to Lose Weight00:35:10 How Much Will You Pay To Lose Weight00:43:55 Thank You, Follow LEALY00:44:13 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
What Is Cultivated Meat and How Do You Grow Meat From Cells: Dr. Nicole Kleger, sallea
Sep 24 2024
What Is Cultivated Meat and How Do You Grow Meat From Cells: Dr. Nicole Kleger, sallea
Cultured meat or cultivated meat, made from cells, is not science-fiction any more.It is pure science.Though I could not help but thinking about Nancy Kress science-fiction book Beggars and Choosers when preparing to this episode. She writes about a world in 2106 where the society is split into a ruling class of Donkeys, who have access to real food, and Livers, who rely on government-provided cheap synthetic and soy-based food. It's just, the current reality of cell-grown meat already looks way more promising than the one in Kress's 1994 novel.What if cultivated meat is healthier and tastes better than meat an animal meat?Would you be tempted by a tasty steak grown in a lab?In this episode, you’ll hear aboutwhat is cultivated meat?why it’s called lab meat and beer isn’thow meat is cultivated from cellsdoes it taste like meathow healthy is itand much more.So today’s story isn’t about a medtech, biotech or digital health startup but it did begin with medtech in mind. And it is absolutely fascinating.My guest, Dr. Nicole Kleger is the CEO of sallea. She began working on this project during her Bachelor’s degree in Materials Science and continued through her Master’s and Ph.D. She’s also a deidcated instructor of Bodypump, Bodyattack, and Bodybalance.sallea is a Swiss startup, an ETH Zurich spin-off, developing edible scaffolds to grow cultivated meat. Their scaffolds, which enable cells to grow into meat, promise your taste buds real meat experience – without sacrificing animals.Check out where is sallea on their goal to match the meat structure with taste in cultured meatgo to https://sallea.ch/Timestamps00:02:40 Why Cultivate Meat From Cells?00:04:19 What Is Cellular Agriculture?00:05:18 Where Is Cultivated Meat Produced?00:06:54 How Healthy Is Cultivated Meat?00:08:42 What Does Cultivated Meat Taste Like?00:12:02 From Medtech To Food00:19:00 What Is Cultivated Meat?00:26:26 The Team Behind Swiss Cultured Meat00:41:00 Thank You Follow sallea00:41:46 Follow X-Health.show Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Genetic Testing for Athletes, Health, Longevity: Thomas Roos, AISTS
Sep 17 2024
Genetic Testing for Athletes, Health, Longevity: Thomas Roos, AISTS
If you've ever given up on something because you thought you didn’t have the predisposition, you should listen to this episode.From sports genomics to genetic-based training.Can genes predict sports performance? And injuries in athletes?What is the contribution of genes to sports performance? We're speaking percentages.Can some athletes be too gifted?Can you predict a child’s talent by analyzing their genes?We’ll also be speaking about multiomics: genomics, genetics, proteomics, metabolomics, microbiomegenetic testing for athletes, rare diseases, and longevityidentical twins researchalthletes such as LeBron James, Michael Phelps, and Imane KhelifMy guest, Thomas Roos, is a sports genetics and genetic epidemiology scientist, entrepreneur, a retired professional triathlete, and an identical twin. He studied at Stanford University School of Medicine and has conducted research as part of multiple international consortiums.AISTS or International Academy of Sports Science and Technology, where we’re speaking, was founded by the International Olympic Committee. It brings together experts in medicine, technology, management, economics, law, and sociology.There’s loads to cover in this episode.Timestamps:00:00:18 Thomas Roos and AISTS00:01:19 What Can Your Genes Tell You About Longevity Your Health and Performance00:03:05 Can Genes Predict Athletic Performance00:06:05 Identical Twin Brothers' Genetics00:09:37 Genetic Tests for Children's Talents – Do They Make Sense00:14:02 Genetics and Genomics Definitions00:17:50 What Is Multiomics00:20:51 Genetic Tests for Athletes00:30:22 Genetic Risk Scores for Athletes00:38:19 Favorable Genetic Profiles and Success in Sports00:50:08 Twin Brothers Part After 30 Years: Stanford Twin Research Cohort01:02:12 Joint Research to Beat Alzheimer's01:13:25 Thank You Follow 5 Ironmans To Beat Alzheimer's01:14:38 Follow X-Health.show Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Better Recovery After Ventricular Assist Devices Implantation at End-Stage Heart Failure: Dr. Andreas Kourouklis, COSKIN
Sep 10 2024
Better Recovery After Ventricular Assist Devices Implantation at End-Stage Heart Failure: Dr. Andreas Kourouklis, COSKIN
By helping pumping blood, Ventricular Assist Devices during end-stage heart failure can prolong life. They can be implanted instead of a heart transplant or while waiting for a heart transplant. They may, however, come with some unwanted side effects, such as infections of a wound that doesn’t heal. The reason is that a cable connecting the Ventricular Assist Device to its power source must pass through the skin on the abdomen and remain there.This wound, a small hole in the abdomen, where the cable goes through the skin, would not heal and is therefore susceptible to infections that lead to hospitalization. Why?You’ll hear about it in this episode, as well aswhat Ventricular Assist Devices arehow a wound heals – from mechanical perspectivewhat are mechanical and biological properties of the skinwhat is end-stage heart failurewhat makes a skin-friendly cableand for what else could such a biocompatible cable be usedMy guest, Dr. Andreas Kourouklis, is a co-founder and the CEO of COSKIN. With a Ph.D. in biomaterials for biomedical applications he worked at Princeton University and University of Illinois at Urbana-Champaign before joining ETH Zurich.COSKIN is a Swiss startup that develops a biocompatible medical cable to support end-stage heart failure patients. Unlike today’s cables powering mechanical circulatory support systems such as VADs, it resembles human tissue and prevents infections. Go ahead and follow what they do athttps://www.coskindevices.com/Timestamps:00:00:00 Dr. Andreas Kourouklis and COSKIN00:01:20 What Is End-Stage Heart Failure?00:06:47 Current Treatment for End Stage Heart Failure: Ventricular Assist Devices00:15:02 Challenges Regarding VAD Insertion00:21:23 Developing a Biocompatible Cable00:40:28 Proving Compatibility with Ventricular Assist Devices00:49:15 The COSKIN Team00:49:59 Other Possible Uses of the Biocompatible Cable: Neurostimulators, Catheters, and More00:53:42 Thank You, Follow COSKIN00:54:24 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Boosting Sports Performance with Pupil Control: Dr. Marc Bächinger, myflow
Sep 3 2024
Boosting Sports Performance with Pupil Control: Dr. Marc Bächinger, myflow
This might be a tool that sports psychologists have dreamed of:a way to measure athletes’ mental training efficacyfor boosting sports performance.You know, like when a runner runs slower today than the day beforetheir coach has the data to compare.If that same runner puts less effort into their mental training,their sports psychologist would not know.This is what my guest is working on,giving mental coaches a VR headset and metrics to rely onto help athletes find flow and improve sports performanceYou will hearwhy do professional athletes need mental trainingwhat flow ishow your pupil size changes when you are relaxed or arousedand how by controlling your pupil, you can control your mindDr. Marc Bächinger is the co-founder and CEO of MindMetrix. He is a neuroscientist with a Ph.D. in health sciences and technology who completed his postdoc in pupil-based biofeedback to modulate the arousal system in the human brain.MindMetrix is an early-stage Swiss startup that develops myflow. This Virtual Reality application allows professional athletes and sports psychologists to track, analyze, and optimize mental training by giving feedback on the size of their pupils.Follow myflow’s development and their current call for study participants athttps://www.myflow.ch/Timestamps:0:00 Dr. Marc Bächinger and myflow1:19 What is Flow?7:28 Mental Training in Professional Athletes13:08 How to Measure Mental Training Efficacy17:03 Locus Coeruleus Pupil and Control Over Arousal Level24:01 Family History and the Pursuit of Neuroscience26:18 Sports Psychologists and Training the Pupil33:20 VR-Supported Biofeedback Method for Relaxation and Activation39:28 Noa Loosli Swiss Football Player45:42 Call for Study Participants48:02 Thank You Follow myflow48:28 Follow X-Health.show Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Repairing Spinal Cord for a Wheelchair Free Future: Prof. Giuseppe Perale, Regenera
Aug 27 2024
Repairing Spinal Cord for a Wheelchair Free Future: Prof. Giuseppe Perale, Regenera
We are speaking about the world where wheelchairs will not be needed after a spinal cord injury.There are 250 000-500 000 spinal cord injuries globally each year.“A bunch of crazy guys,” in the words of my guest, him included, wants the spinal cord to self-regenerate.He is sure that in the future, we won’t be even speaking about regenerating the spinal cord after an accidentbut about healing.In this episode, you will hearhow much time it takes from a spinal cord injury event, an accident, to reach an operating theatre – in Switzerlandwhy this time is crucialhow proprietary hydrogel and stem cells stop the cascade of events further damaging the spinal cordhow mice after a spinal cord injury, could walk againand when will people after the spinal cord injury not need a wheelchairProf. Giuseppe Perale is the CEO of Regenera. A bioengineer who became hooked on regenerative medicine in high school and never let go. Apart from heading the neuroregeneration research lab at USI, Università della Svizzera italiana, he is also a motorcycle rider and a pilot. Regenera is an Austrian-Swiss startup that aims to repair spinal cord injury in the subacute state. Their SpinoSave combines biomaterial – hydrogel and stem cells harvested from the patient’s fat tissue. The co-founders are Giuseppe Perale; Filippo Rossi, a chemical engineer; Pietro Rossi; Michael Raghunath, CMO.Visit their website to stay up to date with progress in regenerating the spinal cord:https://regenera.at/Timestamps:0:00 Prof. Giuseppe Perale and Regenera1:10 Making Paralysis a Thing of the Past3:17 What Causes Spinal Cord Injuries5:44 What Is Paraplegia, What Is Tetraplegia10:02 What Happens in the ER after a Spinal Cord Injury17:56 Regenerative Medicine to Restore Damaged Tissue26:59 Paraplegic Mice Could Walk Again, When Will People 35:35 Why Time Matters after a Spinal Cord Accident39:21 Stopping the Cascade of Events in the Acute Spinal Cord Injury Phase to Induce Self-Regeneration54:36 Preparing for Clinical Studies56:55 Restoring Movement after Spinal Cord Injury in the Future1:00:29 Thank You, Follow Regenera1:01:25 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Psychedelics to Treat Addiction: Dr. Dario Dornbierer, Reconnect Labs
Aug 20 2024
Psychedelics to Treat Addiction: Dr. Dario Dornbierer, Reconnect Labs
How do you design a psychedelic trip that is predictable and effective?That frees people from cocaine addictionWithout the common current side effects of psychedelicsJust imagine being free from an addiction in a few hoursThis is what researchers and my guest today are trying to accomplishYou’ll hearhow did psychedelic studies continue in Switzerland while banned elsewherethe differences between various psychedelicswhat is ayahuasca and its DMT ingredienthow do magic mushrooms and psilocybin workLSDecstasyand the potential of psychedelics in treating depression, anxiety, and cocaine addictionMy guest, Dr. Dario Dornbierer, is the Chief Scientific Officer and a co-founder of Reconnect Labs. A psychopharmacologist who’s done his post-doc research in psychedelics – drug development in mental health.Reconnect Labs is a clinical-stage Swiss startup, a spin-off of the University of Zurich, developing psychedelic medicines for sleep, anxiety, and substance use disorders. This opens a new era in psychiatry: precision therapeutics with both immediate and long-term symptom alleviation.Hit play to step into a sleep lab, where it all started.Learn more about Reconnect Labs at:https://www.reconnect-labs.com/Timestamps0:00 Dr. Dario Dornbierer and Reconnect Labs1:19 Where Are Psychedelics Legal: LSD, Psylocybin, Ayahuasca3:40 Psychedelics to Aid Psychiatry6:02 What Are Psychedelics?12:45 How Do Psychedelics Work?16:03 What Is Ayahuasca? 20:59 The Potential of Psychedelics in Depression, Anxiety, Addictive Disorders26:40 Psilocybin vs DMT and Harmine28:29 Set and Setting of a Psychedelic Trip36:48 Developing a Predictable Trip with a Therapeutic Effect42:28 Treating Addiction with Psychedelics1:00:59 Thank You, Follow Reconnect Labs1:01:53 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Longevity, Reversing and Slowing Down Aging: Sophie Chabloz, Avea
Aug 13 2024
Longevity, Reversing and Slowing Down Aging: Sophie Chabloz, Avea
There are people who believe that stopping aging will be possible.For now,we can already speak aboutslowing down agingor evenreversing aging – as Bryan Johnson set off to accomplish waving his "Don't Die" slogan.In this episode, you’ll hear aboutis collagen good for you?vegan collagen precursorat what age the production of some coenzymes slows down – meaning how early your body begins to age – you will be surprised how early!NMNcoenzyme Q10, resveratrol, probiotics, melatoninas well as skin healthjoint health blood sugargut and brain healthenergyand overall, longevity and healthspanMy guest, Sophie Chabloz, is a co-founder and Chief Science Officer at AVEA. A Food Science, Nutrition and Health expert. A mom. Used to teach yoga. She makes sure the supplement formulations make sense.AVEA is a Swiss startup that launched a range of science-based longevity supplements. Among them, their collagen activator – a vegan collagen precursor.Here is where you can find them:https://avea-life.com/Timestamps:0:00 Sophie Chabloz and Avea1:14 Is Collagen Good for You?10:52 What Compounds and Coenzymes Do We Lose When Aging?16:35 Melatonin as an Antioxidant21:36 Supplements vs Nutraceuticals26:28 Vegan Collagen Precursor38:36 Improving Joint Health40:41 Science Behind Longevity Supplement Formulas49:27 Longevity Supplements Shipped Worldwide55:14 Thank You, Follow Avea55:42 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Supporting Surgeons in Fetal Surgeries: Dr. Yannick Devaud, KOVE medical
Aug 6 2024
Supporting Surgeons in Fetal Surgeries: Dr. Yannick Devaud, KOVE medical
Fetal surgeons save the life of a fetus with a birth defect– or improve the outcomes after birth –operating while still in utero.In a woman’s womb.Unsolvable so far – a hole in an amniotic sac after the surgerywhich causes preterm births.But here is where bioengineers have stepped into support the surgeons.In this episode, you’ll hear about fetal abnormalities that can be addressed by surgeries before a child is bornspina bifidatwin-to-twin transfusion syndromecongenital diaphragmatic herniahow fetal surgeries are performedand how to prevent the side effect of fetal surgery, which is premature birthOur guest, Dr. Yannick Devaud is the founder and CEO of KOVE medical. With a PhD in bioengineering and biotechnology, he embarked on a mission to develop a medical device for minimally invasive fetal surgery.KOVE medical is a Swiss startup that develops a device to reduce the risk of preterm birth following surgeries on the fetus during pregnancy.Here is more about themhttps://kovemedical.com/Timestamps:0:00 Dr. Yannick Devaud and KOVE medical1:20 World Fetal Medicine Foundation Congress in Lisbon3:06 What Are Fetal Surgeries13:03 Risks of Fetal Surgeries17:44 Calling a Bioengineer to Prevent the Premature Birth26:39 How to Stitch a Whole in an Amniotic Sack After a Fetal Surgery28:45 Collaborations with the University Hospital Zurich and Centers Around the World35:31 Future of the KOVE Device to Support Fetal Surgeons46:27 Thank You, Follow KOVE medical47:16 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
New Treatment for Oral Mucositis in Cancer: Dr. Pierre Morgon, Ibex Therapeutics
Jul 30 2024
New Treatment for Oral Mucositis in Cancer: Dr. Pierre Morgon, Ibex Therapeutics
The pain in your mouth is so bad that you cannot even drink, let alone eat.What is horrifying is that 50-80% of cancer patients undergoing chemo or radiotherapy can experience it – oral mucositis.And there is no approved treatment.This is what you’ll hear in this episodehow a cute-looking willowherb grown in the Swiss Alps is making its way from traditional medicine to prescription medicine – to treat oral mucositis, especially in cancer patientsand in the long term, more broadly – fungal infectionsMy guest today is Dr. Pierre Morgon, the CEO of Ibex Therapeutics. With a PhD in pharmacy, he has held numerous senior positions in the life sciences industry and currently serves on the boards of biotech, medtech, and healthcare IT startups.He decided to co-found Ibex Therapeutics, a Swiss startup that aims to alleviate the debilitating oral pain that often results from chemotherapies and radiotherapies. To combat oral mucositis, they employed a plant native to the Swiss Alps.Here’s more about them if you’re curious:https://ibextx.ch/en/Timestamps:0:00 Dr. Pierre Morgon and Ibex Therapeutics1:18 Willowherb from the Swiss Alps3:00 What is Oral Mucositis11:01 Discovery of Epilobium Parviflorum Antifungal Properties: the Discovery 20:49 Clear Unmet Need + Experienced Founders25:32 Mouth Wash for Oral Mucositis: First Studies in Patients33:34 Market Availability: Cosmetic and Pharmaceutical Products43:15 Plant-Based Medicine49:02 Thank You, Follow Ibex Therapeutics 49:34 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.
Goal – Deliver Cancer Drugs Faster: Dr. Marie-Agnès Doucey, Calico Biosystems
Jul 23 2024
Goal – Deliver Cancer Drugs Faster: Dr. Marie-Agnès Doucey, Calico Biosystems
Do you know what is the % of cancer drug candidates that fail in human trials?Guess, and I bet you underestimated it.This is what we speak at the beginning of this episode and what my guest wants to change dramatically.You will also hear about:the % of patients that actually benefit from approved cancer drug therapies (spoiler: so so low)cancer monotherapies vs. cancer combination therapieshow to reproduce the human cancer ecosystem from a tumorprecision oncologymultiomics analysisand how to bring cancer drugs faster to patientsDr. Marie-Agnès Doucey, the co-founder of Calico Biosystems, is a biotechnology engineer with a PhD in biochemistry.  She has over 15 years of experience in R&D and drug development programs in oncology.Calico Biosystems is a Swiss startup developing a drug testing platform that uses patients’ tumors, multiomics profiling, and computational modeling to predict the clinical efficacy of anti-cancer drugs at the pre-clinical stage. Radically accelerating drug development.Here is their website:https://calicobiosystems.com/ 0:00 Dr. Marie-Agnès Doucey and Calico Biosystems1:15 Why Only 10% of Cancer Patients Benefit from Therapies9:00 Complexity of Experimental Oncology12:50 Cancer Monotherapies vs. Cancer Combination Therapies15:11 How to Reproduce Human Cancer Ecosystem17:10 What is Precision Oncology20:35 Platform for Cancer Drug Developers Instead of Animal Models32:34 Collaboration with the University of Lausanne37:49 What is Multiomics Analysis40:35 De-risking Clinical Studies and Moving to the Clinical Stage47:16 More Than a Decade of Research to Found a Startup53:07 Thank You, Follow Calico Biosystems53:55 Follow X-Health.show, Disclaimer If you've enjoyed listening, you'll make us happy by clicking "Follow" on X-Health.show and leaving a review.The information in this podcast is for informational purposes only and should not be considered medical advice. If you have any medical questions, please consult your healthcare practitioner. The opinions on the show are Alex's or her guests. The podcast does not make any responsibility or warranties about guests statements or credibility. While the podcast makes every effort to ensure that the information shared is accurate, please let us know if you have any comments, suggestions or corrections.